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Page 1
Anaplastic Lymphoma Kinase as a Cancer Target in Pediatric Malignancies.
Mossé YP. Mossé YP. Clin Cancer Res. 2016 Feb 1;22(3):546-52. doi: 10.1158/1078-0432.CCR-14-1100. Epub 2015 Oct 26. Clin Cancer Res. 2016. PMID: 26503946 Free PMC article. Review.
The discovery of activating kinase domain mutations of the full-length ALK receptor as the major cause of hereditary neuroblastoma, and that somatically acquired mutations and amplification events often drive the malignant process in a subset of sporadic tumors, has …
The discovery of activating kinase domain mutations of the full-length ALK receptor as the major cause of hereditary neuroblastoma …
Neuroblastoma in monozygotic twins with distinct presentation pathology and outcome: is it familial or in utero metastasis.
Abu-Arja R, Hashem H, El-Sheikh A, Abusin G. Abu-Arja R, et al. Pediatr Blood Cancer. 2014 Jun;61(6):1124-5. doi: 10.1002/pbc.24906. Epub 2013 Dec 23. Pediatr Blood Cancer. 2014. PMID: 24376049 Review.
Twin-to-twin in utero metastasis have been proposed as the mechanism of tumor development in the second twin; based on similar pathology, presence of metastatic disease, absence of a primary tumor, and/or later presentation in the second twin. Hereditary neuroblastoma …
Twin-to-twin in utero metastasis have been proposed as the mechanism of tumor development in the second twin; based on similar pathology, pr …