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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1992 1
1993 1
1995 1
1996 3
1998 2
1999 4
2001 1
2002 3
2003 1
2004 2
2005 2
2007 1
2024 0

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Page 1
Hereditary nonpolyposis colorectal cancer (Lynch syndrome): criteria for identification and management.
Kouraklis G, Misiakos EP. Kouraklis G, et al. Dig Dis Sci. 2005 Feb;50(2):336-44. doi: 10.1007/s10620-005-1607-z. Dig Dis Sci. 2005. PMID: 15745097 Review.
Usually the carcinomas are synchronous or metachronous, and most of them arise proximal to the splenic flexure. The prognosis is better than for the sporadic form of cancer, and there is increased risk for cancer development in certain extracolonic sites, such as the endom …
Usually the carcinomas are synchronous or metachronous, and most of them arise proximal to the splenic flexure. The prognosis is bett …
Familial sarcoma: challenging pedigrees.
Lynch HT, Deters CA, Hogg D, Lynch JF, Kinarsky Y, Gatalica Z. Lynch HT, et al. Cancer. 2003 Nov 1;98(9):1947-57. doi: 10.1002/cncr.11743. Cancer. 2003. PMID: 14584079 Free article.
BACKGROUND: Partially due to the rare occurrence of soft tissue and osteogenic sarcomas in the general population, scant attention has been given to their hereditary etiology. Their overall poor prognosis might be ameliorated through an understanding of their environmental …
BACKGROUND: Partially due to the rare occurrence of soft tissue and osteogenic sarcomas in the general population, scant attention has been …
Evaluation of screening strategy for detecting hereditary nonpolyposis colorectal carcinoma.
Furukawa T, Konishi F, Shitoh K, Kojima M, Nagai H, Tsukamoto T. Furukawa T, et al. Cancer. 2002 Feb 15;94(4):911-20. Cancer. 2002. PMID: 11920458 Free article.
Immunohistochemically, a decreased nuclear staining was found in 57.3% (47 of 82) for hMLH1 and in 18.3% (15 of 82) for hMSH2. The frequency of predicted germline mutations was higher in cases with decreased hMSH2 than hMLH1 (33.3% vs. 6.4%; P = 0.016). ...
Immunohistochemically, a decreased nuclear staining was found in 57.3% (47 of 82) for hMLH1 and in 18.3% (15 of 82) for hMSH2. The frequency …
Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.
Hendriks YM, Wagner A, Morreau H, Menko F, Stormorken A, Quehenberger F, Sandkuijl L, Møller P, Genuardi M, Van Houwelingen H, Tops C, Van Puijenbroek M, Verkuijlen P, Kenter G, Van Mil A, Meijers-Heijboer H, Tan GB, Breuning MH, Fodde R, Wijnen JT, Bröcker-Vriends AH, Vasen H. Hendriks YM, et al. Gastroenterology. 2004 Jul;127(1):17-25. doi: 10.1053/j.gastro.2004.03.068. Gastroenterology. 2004. PMID: 15236168
MSI analysis in colorectal tumors had a sensitivity of 86% in predicting a MMR defect. IHC in all tumors had a sensitivity of 90% in predicting a mutation in MSH6. ...
MSI analysis in colorectal tumors had a sensitivity of 86% in predicting a MMR defect. IHC in all tumors had a sensitivity of 90% in …
23 results