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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1935 1
1951 1
1954 1
1963 1
1969 1
1970 1
1971 1
1975 4
1976 3
1977 4
1979 4
1980 7
1981 7
1982 2
1983 2
1985 3
1986 5
1987 3
1988 4
1989 4
1990 4
1991 1
1992 3
1993 4
1994 2
1995 3
1996 1
1997 5
1998 2
1999 5
2000 4
2001 3
2002 11
2003 6
2004 9
2005 4
2006 7
2007 5
2008 4
2009 5
2010 3
2011 8
2012 4
2013 1
2014 2
2015 9
2016 10
2017 6
2018 7
2019 9
2020 3
2021 2
2022 1
2023 3
2024 1

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203 results

Results by year

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Page 1
Histamine dihydrochloride: in the management of acute myeloid leukaemia.
Yang LP, Perry CM. Yang LP, et al. Drugs. 2011 Jan 1;71(1):109-22. doi: 10.2165/11206410-000000000-00000. Drugs. 2011. PMID: 21175244 Review.
Histamine dihydrochloride (Ceplene) is a synthetic derivative of the biogenic amine histamine. Histamine dihydrochloride inhibits the formation of reactive oxygen species that suppress the activation of T cells and natural killer cells. ...
Histamine dihydrochloride (Ceplene) is a synthetic derivative of the biogenic amine histamine. Histamine dihydrochlo
Spotlight on histamine dihydrochloride in acute myeloid leukaemia.
Yang LP, Perry CM. Yang LP, et al. Drugs Aging. 2011 Apr 1;28(4):325-9. doi: 10.2165/11206810-000000000-00000. Drugs Aging. 2011. PMID: 21428467 Review.
Histamine dihydrochloride (Ceplene) is a synthetic derivative of the biogenic amine histamine. Histamine dihydrochloride inhibits the formation of reactive oxygen species that suppress the activation of T cells and natural killer (NK) cells. ...
Histamine dihydrochloride (Ceplene) is a synthetic derivative of the biogenic amine histamine. Histamine dihydrochlo
Histamine dihydrochloride and low-dose interleukin-2 as post-consolidation immunotherapy in acute myeloid leukemia.
Thorén FB, Romero AI, Brune M, Hellstrand K. Thorén FB, et al. Expert Opin Biol Ther. 2009 Sep;9(9):1217-23. doi: 10.1517/14712590903130566. Expert Opin Biol Ther. 2009. PMID: 19653866 Review.
A therapy that boosts the function of these effector cells therefore has the potential to eradicate the malignant clone in AML and prevent relapse, Here, we briefly review the literature on the role of the immune system in AML and introduce the rationale for the use of histami
A therapy that boosts the function of these effector cells therefore has the potential to eradicate the malignant clone in AML and prevent r …
Histamine dihydrochloride for the treatment of acute myeloid leukemia, malignant melanoma and renal cell carcinoma.
Perz JB, Ho AD. Perz JB, et al. Future Oncol. 2008 Apr;4(2):169-77. doi: 10.2217/14796694.4.2.169. Future Oncol. 2008. PMID: 18407731 Review.
Histamine dihydrochloride is a vasoactive biogenic amine. It inhibits the reactive oxygen species formation in monocytes via histamine H2 receptors and protects natural killer and T cells from oxidative damage. ...On the other hand, less promising results were repor
Histamine dihydrochloride is a vasoactive biogenic amine. It inhibits the reactive oxygen species formation in monocytes via h
Histamine dihydrochloride (subcutaneous) Maxim.
Galmarini CM. Galmarini CM. Curr Opin Investig Drugs. 2004 Dec;5(12):1298-310. Curr Opin Investig Drugs. 2004. PMID: 15648952 Review.
Maxim is developing a subcutaneous formulation of histamine dihydrochloride (Ceplene, formerly known as Maxamine) for use as an adjuvant with interleukin (IL)-2 therapy for the potential treatment of metastatic melanoma, hepatitis C virus infection, acute myelogenou …
Maxim is developing a subcutaneous formulation of histamine dihydrochloride (Ceplene, formerly known as Maxamine) for use as a …
Histamine dihydrochloride: actions and efficacy in the treatment of chronic hepatitis C infection.
Lalazar G, Ilan Y. Lalazar G, et al. Expert Rev Anti Infect Ther. 2006 Jun;4(3):377-85. doi: 10.1586/14787210.4.3.377. Expert Rev Anti Infect Ther. 2006. PMID: 16771615 Review.
Current therapies for genotype 1 are unsuccessful in a substantial number of patients. Histamine dihydrochloride by virtue of its histamine H2 agonistic activity, has the potential to prevent damage induced by oxidative stress in tissues and can protect T and natura …
Current therapies for genotype 1 are unsuccessful in a substantial number of patients. Histamine dihydrochloride by virtue of …
Histamine dihydrochloride and interleukin-2 in the treatment of acute myeloid leukemia.
Stadtmauer EA. Stadtmauer EA. Semin Oncol. 2002 Jun;29(3 Suppl 7):47-51. doi: 10.1053/sonc.2002.33084. Semin Oncol. 2002. PMID: 12068389 Review.
Recently, agents capable of modulating cytotoxic effector function have been identified, including histamine dihydrochloride, which has been shown to act as an inhibitor of cellular-mediated free-radical production. ...
Recently, agents capable of modulating cytotoxic effector function have been identified, including histamine dihydrochloride, …
Immunotherapy with histamine dihydrochloride for the prevention of relapse in acute myeloid leukemia.
Martner A, Thorén FB, Aurelius J, Söderholm J, Brune M, Hellstrand K. Martner A, et al. Expert Rev Hematol. 2010 Aug;3(4):381-91. doi: 10.1586/ehm.10.30. Expert Rev Hematol. 2010. PMID: 21083028 Review.
Despite ensuing courses of consolidation chemotherapy, a large fraction of patients will experience relapses with poor prospects of long-term survival. Histamine dihydrochloride (HDC) in combination with the T-cell-derived cytokine IL-2 was recently approved within …
Despite ensuing courses of consolidation chemotherapy, a large fraction of patients will experience relapses with poor prospects of long-ter …
203 results