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Persistent humoral immune defect in highly active antiretroviral therapy-treated children with HIV-1 infection: loss of specific antibodies against attenuated vaccine strains and natural viral infection.
Bekker V, Scherpbier H, Pajkrt D, Jurriaans S, Zaaijer H, Kuijpers TW. Bekker V, et al. Pediatrics. 2006 Aug;118(2):e315-22. doi: 10.1542/peds.2005-2616. Epub 2006 Jul 17. Pediatrics. 2006. PMID: 16847077
METHODS: In a prospective, single-center, cohort study of 59 children with HIV-1 infection, we investigated the long-term effect of highly active antiretroviral therapy on the titers and course of specific antibodies against measles, mumps, and rubella vaccine strains comp …
METHODS: In a prospective, single-center, cohort study of 59 children with HIV-1 infection, we investigated the long-term effect of highly a …
The defect in humoral immunity in patients with Nijmegen breakage syndrome is explained by defects in peripheral B lymphocyte maturation.
Piątosa B, van der Burg M, Siewiera K, Pac M, van Dongen JJ, Langerak AW, Chrzanowska KH, Bernatowska E. Piątosa B, et al. Cytometry A. 2012 Oct;81(10):835-42. doi: 10.1002/cyto.a.22108. Epub 2012 Jul 31. Cytometry A. 2012. PMID: 22851427 Free article.
Patients with an immunodeficiency in the course of Nijmegen breakage syndrome (NBS) that is caused by mutations in the NBN/NBS1 gene are prone to recurrent infections and malignancies, due to a defective DNA double-strand breaks repair mechanism. ...
Patients with an immunodeficiency in the course of Nijmegen breakage syndrome (NBS) that is caused by mutations in the NBN/NBS1 gene …