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Quoted phrase not found in phrase index: "Hydatidiform mole, recurrent, 1"
Page 1
Diagnosis and management of gestational trophoblastic disease: 2021 update.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L. Ngan HYS, et al. Int J Gynaecol Obstet. 2021 Oct;155 Suppl 1(Suppl 1):86-93. doi: 10.1002/ijgo.13877. Int J Gynaecol Obstet. 2021. PMID: 34669197 Free PMC article.
The duration of hCG monitoring varies depending on histological type and regression rate. Low-risk GTN (FIGO Stages I-III: score <7) is treated with single-agent chemotherapy but may require additional agents; although scores 5-6 are associated with more drug res …
The duration of hCG monitoring varies depending on histological type and regression rate. Low-risk GTN (FIGO Stages I-III: score < …
Guideline No. 408: Management of Gestational Trophoblastic Diseases.
Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier P. Eiriksson L, et al. J Obstet Gynaecol Can. 2021 Jan;43(1):91-105.e1. doi: 10.1016/j.jogc.2020.03.001. J Obstet Gynaecol Can. 2021. PMID: 33384141 Review.
EVIDENCE: Relevant studies from 2002 onwards were searched in Embase, MEDLINE, the Cochrane Central Register of Controlled Trials, and Cochrane Systematic Reviews using the following terms, either alone or in combination: trophoblastic neoplasms, choriocarcinoma, trophoblastic tu …
EVIDENCE: Relevant studies from 2002 onwards were searched in Embase, MEDLINE, the Cochrane Central Register of Controlled Trials, and Cochr …
Update on the diagnosis and management of gestational trophoblastic disease.
Ngan HYS, Seckl MJ, Berkowitz RS, Xiang Y, Golfier F, Sekharan PK, Lurain JR, Massuger L. Ngan HYS, et al. Int J Gynaecol Obstet. 2018 Oct;143 Suppl 2:79-85. doi: 10.1002/ijgo.12615. Int J Gynaecol Obstet. 2018. PMID: 30306586
The duration of hCG monitoring varies depending on histology type and regression rate. Low-risk GTN (FIGO Stages I-III: score <7) is treated with single-agent chemotherapy but may require additional agents; although scores 5-6 are associated with more drug resist …
The duration of hCG monitoring varies depending on histology type and regression rate. Low-risk GTN (FIGO Stages I-III: score <7) …
Triploid pregnancy-Clinical implications.
Massalska D, Bijok J, Kucińska-Chahwan A, Zimowski JG, Ozdarska K, Panek G, Roszkowski T. Massalska D, et al. Clin Genet. 2021 Oct;100(4):368-375. doi: 10.1111/cge.14003. Epub 2021 Jun 1. Clin Genet. 2021. PMID: 34031868 Review.
Triploidy is a life-limiting genetic aberration resulting from an extra haploid set of chromosomes of paternal (diandric triploidy) or maternal origin (digynic triploidy). Triploidy affects around 1%-2% of all conceptions. The majority of cases is miscarried at early devel …
Triploidy is a life-limiting genetic aberration resulting from an extra haploid set of chromosomes of paternal (diandric triploidy) or mater …
Treatments and outcomes in high-risk gestational trophoblastic neoplasia: A systematic review and meta-analysis.
Albright BB, Ellett T, Knochenhauer HE, Goins EC, Monuszko KA, Kaplan SJ, Previs RA, Moss HA, Havrilesky LJ, Davidson BA. Albright BB, et al. BJOG. 2023 Apr;130(5):443-453. doi: 10.1111/1471-0528.17374. Epub 2023 Jan 25. BJOG. 2023. PMID: 36648416 Free PMC article. Review.
Limited published institutional data has yet to be systematically reviewed. OBJECTIVES: To compile global high-risk GTN (prognostic score 7) cohorts to summarise treatments and outcomes by disease characteristics and primary chemotherapy. ...Across 24 reporting studies, mo …
Limited published institutional data has yet to be systematically reviewed. OBJECTIVES: To compile global high-risk GTN (prognostic score …
The genomic basis of sporadic and recurrent pregnancy loss: a comprehensive in-depth analysis of 24,900 miscarriages.
Finley J, Hay S, Oldzej J, Meredith MM, Dzidic N, Slim R, Aradhya S, Hovanes K, Sahoo T. Finley J, et al. Reprod Biomed Online. 2022 Jul;45(1):125-134. doi: 10.1016/j.rbmo.2022.03.014. Epub 2022 Mar 23. Reprod Biomed Online. 2022. PMID: 35523710
RESULTS: Sporadic miscarriage (64.7%) or recurrent pregnancy loss (RPL) (22%) were the most common referrals. Clinically significant abnormalities were observed in 55.8% (13,910) of samples, variants of uncertain significance in 1.8%, and normal results in 42 …
RESULTS: Sporadic miscarriage (64.7%) or recurrent pregnancy loss (RPL) (22%) were the most common referrals. Clinically significant …
Obstetrics outcomes after complete and partial molar pregnancy: Review of the literature and meta-analysis.
Capozzi VA, Butera D, Armano G, Monfardini L, Gaiano M, Gambino G, Sozzi G, Merisio C, Berretta R. Capozzi VA, et al. Eur J Obstet Gynecol Reprod Biol. 2021 Apr;259:18-25. doi: 10.1016/j.ejogrb.2021.01.051. Epub 2021 Jan 29. Eur J Obstet Gynecol Reprod Biol. 2021. PMID: 33550107 Review.
The hydatidiform mole is a rare gynecological disease rising from the trophoblastic. ...Six studies met the inclusion. Of the total 25,222 patients, 13,129 complete (52.1 %) and 12,093 partial (47.9 %) molar pregnancies were included. ...
The hydatidiform mole is a rare gynecological disease rising from the trophoblastic. ...Six studies met the inclusion. Of the …
KH domain containing 3 like (KHDC3L) frame-shift mutation causes both recurrent pregnancy loss and hydatidiform mole.
Fatemi N, Ray PF, Ramezanali F, Shahani T, Amiri-Yekta A, Kherraf ZE, Cazin C, Almadani N, Varkiani M, Sarmadi S, Sodeifi N, Gourabi H, Biglari A, Totonchi M. Fatemi N, et al. Eur J Obstet Gynecol Reprod Biol. 2021 Apr;259:100-104. doi: 10.1016/j.ejogrb.2021.02.006. Epub 2021 Feb 10. Eur J Obstet Gynecol Reprod Biol. 2021. PMID: 33639414
OBJECTIVE: Recurrent pregnancy loss (RPL) is a common infertility-related complication that affects approximately 1-3 % of women worldwide. ...STUDY DESIGN: Using whole-exome sequencing (WES), we studied a large multiplex consanguineous family with multiple cases of …
OBJECTIVE: Recurrent pregnancy loss (RPL) is a common infertility-related complication that affects approximately 1-3 % of wom …
Live births in women with recurrent hydatidiform mole and two NLRP7 mutations.
Akoury E, Gupta N, Bagga R, Brown S, Déry C, Kabra M, Srinivasan R, Slim R. Akoury E, et al. Reprod Biomed Online. 2015 Jul;31(1):120-4. doi: 10.1016/j.rbmo.2015.03.011. Epub 2015 Apr 16. Reprod Biomed Online. 2015. PMID: 25982095
Hydatidiform mole (HM) is an aberrant human pregnancy with abnormal embryonic development and excessive proliferation of the trophoblast. Recessive mutations in NLRP7 are responsible for recurrent HM (RHM). Women with recessive NLRP7 mutations fail to have no …
Hydatidiform mole (HM) is an aberrant human pregnancy with abnormal embryonic development and excessive proliferation of the t …
A KHDC3L mutation resulting in recurrent hydatidiform mole causes genome-wide DNA methylation loss in oocytes and persistent imprinting defects post-fertilisation.
Demond H, Anvar Z, Jahromi BN, Sparago A, Verma A, Davari M, Calzari L, Russo S, Jahromi MA, Monk D, Andrews S, Riccio A, Kelsey G. Demond H, et al. Genome Med. 2019 Dec 17;11(1):84. doi: 10.1186/s13073-019-0694-y. Genome Med. 2019. PMID: 31847873 Free PMC article.
BACKGROUND: Maternal effect mutations in the components of the subcortical maternal complex (SCMC) of the human oocyte can cause early embryonic failure, gestational abnormalities and recurrent pregnancy loss. Enigmatically, they are also associated with DNA methylation ab …
BACKGROUND: Maternal effect mutations in the components of the subcortical maternal complex (SCMC) of the human oocyte can cause early embry …
30 results