Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1981 1
1990 1
1993 1
1994 3
1995 1
2000 1
2003 1
2004 5
2005 4
2006 1
2007 4
2008 1
2009 2
2010 1
2011 4
2012 9
2013 5
2014 6
2015 6
2016 8
2017 6
2018 7
2019 10
2020 6
2021 11
2022 6
2023 5
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

59 results

Results by year

Filters applied: Meta-Analysis, Review, Systematic Review, in the last 10 years. Clear all
Page 1
17 Alpha-hydroxyprogesterone caproate use in a rural state.
Ghahremani T, Phillips A, Magann EF, McCoy H, Whittington J, Ounpraseuth S, Eswaran H. Ghahremani T, et al. J Matern Fetal Neonatal Med. 2022 Dec;35(25):6437-6439. doi: 10.1080/14767058.2021.1914579. Epub 2021 Apr 25. J Matern Fetal Neonatal Med. 2022. PMID: 33899652 Review.
BACKGROUND: 17 alpha-hydroxyprogesterone caproate (17OHP) is used to reduce the recurrent risk of preterm delivery in women with a history of preterm delivery. ...
BACKGROUND: 17 alpha-hydroxyprogesterone caproate (17OHP) is used to reduce the recurrent risk of preterm delivery in women wi …
17-Hydroxyprogesterone caproate in triplet pregnancy: an individual patient data meta-analysis.
Combs CA, Schuit E, Caritis SN, Lim AC, Garite TJ, Maurel K, Rouse D, Thom E, Tita AT, Mol B; Global Obstetrics Network (GONet) collaboration. Combs CA, et al. BJOG. 2016 Apr;123(5):682-90. doi: 10.1111/1471-0528.13779. Epub 2015 Dec 10. BJOG. 2016. PMID: 26663620 Free PMC article. Review.
OBJECTIVE: To determine, using individual patient data (IPD) meta-analysis, whether the outcome of triplet pregnancy is affected by prophylactic administration of 17-hydroxyprogesterone caproate (17OHPc). SEARCH STRATEGY: We searched literature databases, trial regi …
OBJECTIVE: To determine, using individual patient data (IPD) meta-analysis, whether the outcome of triplet pregnancy is affected by prophyla …
Adjuvant 17-hydroxyprogesterone caproate in women with history-indicated cerclage: A systematic review and meta-analysis.
Eke AC, Sheffield J, Graham EM. Eke AC, et al. Acta Obstet Gynecol Scand. 2019 Feb;98(2):139-153. doi: 10.1111/aogs.13488. Epub 2018 Nov 18. Acta Obstet Gynecol Scand. 2019. PMID: 30339274 Free PMC article. Review.
INTRODUCTION: The purpose of this study was to evaluate whether there are additional benefits of 17-hydroxyprogesterone caproate (17-OHPC) supplementation in preventing recurrent spontaneous preterm birth in women with a prophylactic cerclage. ...Keywords included " …
INTRODUCTION: The purpose of this study was to evaluate whether there are additional benefits of 17-hydroxyprogesterone caproate …
Safety review of hydroxyprogesterone caproate in women with a history of spontaneous preterm birth.
Sibai B, Saade GR, Das AF, Gudeman J. Sibai B, et al. J Perinatol. 2021 Apr;41(4):718-725. doi: 10.1038/s41372-020-00849-y. Epub 2020 Oct 14. J Perinatol. 2021. PMID: 33057132 Free PMC article. Review.
17-alpha-hydroxyprogesterone caproate (17P) has been in use for prevention of recurrent preterm birth since 2003 when the Meis trial was published. ...
17-alpha-hydroxyprogesterone caproate (17P) has been in use for prevention of recurrent preterm birth since 2003 when the Meis …
17-alpha hydroxyprogesterone caproate for preterm birth prevention: Where have we been, how did we get here, and where are we going?
Manuck TA. Manuck TA. Semin Perinatol. 2017 Dec;41(8):461-467. doi: 10.1053/j.semperi.2017.08.004. Epub 2017 Sep 22. Semin Perinatol. 2017. PMID: 28947068 Review.
In general, progesterone is thought to maintain pregnancy through several closely linked mechanisms: (1) promotion of uterine quiescence, (2) inhibition of pro-inflammatory cells, and (3) immunosuppressive action. 17-Alpha hydroxyprogesterone caproate is currently t …
In general, progesterone is thought to maintain pregnancy through several closely linked mechanisms: (1) promotion of uterine quiescence, (2 …
Progesterone and preterm birth.
Norman JE. Norman JE. Int J Gynaecol Obstet. 2020 Jul;150(1):24-30. doi: 10.1002/ijgo.13187. Int J Gynaecol Obstet. 2020. PMID: 32524598 Free PMC article. Review.
Progestogens (vaginal progesterone and intramuscular 17-hydroxyprogesterone acetate) are widely recommended for women at high risk of preterm birth. Typical regimens include 17-hydroxyprogesterone caproate (250 mg intramuscularly weekly), starting at 16-20 gestation …
Progestogens (vaginal progesterone and intramuscular 17-hydroxyprogesterone acetate) are widely recommended for women at high risk of preter …
Vaginal progesterone compared with intramuscular 17-alpha-hydroxyprogesterone caproate for prevention of recurrent preterm birth in singleton gestations: a systematic review and meta-analysis.
Boelig RC, Locci M, Saccone G, Gragnano E, Berghella V. Boelig RC, et al. Am J Obstet Gynecol MFM. 2022 Sep;4(5):100658. doi: 10.1016/j.ajogmf.2022.100658. Epub 2022 May 10. Am J Obstet Gynecol MFM. 2022. PMID: 35562009 Review.
OBJECTIVE: Randomized trials have found benefits of both vaginal progesterone and 17-alpha-hydroxyprogesterone caproate in the prevention of recurrent preterm birth. ...Perinatal mortality was lower in the vaginal progesterone group than in the 17-alpha-hydroxypr …
OBJECTIVE: Randomized trials have found benefits of both vaginal progesterone and 17-alpha-hydroxyprogesterone caproate in the …
What now? A critical evaluation of over 20 years of clinical and research experience with 17-alpha hydroxyprogesterone caproate for recurrent preterm birth prevention.
Manuck TA, Gyamfi-Bannerman C, Saade G. Manuck TA, et al. Am J Obstet Gynecol MFM. 2023 Oct;5(10):101108. doi: 10.1016/j.ajogmf.2023.101108. Epub 2023 Jul 30. Am J Obstet Gynecol MFM. 2023. PMID: 37527737 Free PMC article. Review.
Supplementation with progestogens, including 17-alpha hydroxyprogesterone caproate has been a mainstay of prematurity prevention strategies in the United States in the last 2 decades. ...In 17-alpha hydroxyprogesterone caproate. The history of the use, …
Supplementation with progestogens, including 17-alpha hydroxyprogesterone caproate has been a mainstay of prematurity preventi …
Reassessing Preterm Birth Prevention After the Withdrawal of 17-alpha Hydroxyprogesterone Caproate.
Heyborne K. Heyborne K. Obstet Gynecol. 2023 Sep 1;142(3):493-501. doi: 10.1097/AOG.0000000000005290. Epub 2023 Jul 13. Obstet Gynecol. 2023. PMID: 37441790 Review.
Food and Drug Administration has recently withdrawn approval for 17-alpha hydroxyprogesterone caproate for prevention of recurrent preterm birth, and recent studies have called into question benefits of the pessary in the setting of a short cervix. ...
Food and Drug Administration has recently withdrawn approval for 17-alpha hydroxyprogesterone caproate for prevention of recur …
17alpha-Hydroxyprogesterone Caproate and the Risk of Glucose Intolerance in Pregnancy: A Systematic Review and Meta-analysis.
Eke AC, Sheffield J, Graham EM. Eke AC, et al. Obstet Gynecol. 2019 Mar;133(3):468-475. doi: 10.1097/AOG.0000000000003115. Obstet Gynecol. 2019. PMID: 30741815 Free PMC article.
OBJECTIVE: To evaluate whether 17alpha-hydroxyprogesterone caproate use in preventing preterm birth increases the risk of gestational diabetes mellitus (GDM). ...Keywords included "gestational diabetes," "preterm birth," "pregnancy," and "17-hydroxyprogesterone …
OBJECTIVE: To evaluate whether 17alpha-hydroxyprogesterone caproate use in preventing preterm birth increases the risk of gest …
59 results