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Page 1
Evidence-based fluid management in the ICU.
Schindler AW, Marx G. Schindler AW, et al. Curr Opin Anaesthesiol. 2016 Apr;29(2):158-65. doi: 10.1097/ACO.0000000000000303. Curr Opin Anaesthesiol. 2016. PMID: 26784351 Review.
In ICU patients, balanced crystalloids should primarily be used, because unbalanced infusions (especially saline) cause hyperchloremic acidosis which is associated with renal impairment and infections. ...
In ICU patients, balanced crystalloids should primarily be used, because unbalanced infusions (especially saline) cause hyperchloremic …
Empagliflozin-associated postoperative mixed metabolic acidosis. Case report and review of pathogenesis.
Sitina M, Lukes M, Sramek V. Sitina M, et al. BMC Endocr Disord. 2023 Apr 14;23(1):81. doi: 10.1186/s12902-023-01339-w. BMC Endocr Disord. 2023. PMID: 37060078 Free PMC article.
The mechanisms are not fully understood but involve increased ketogenesis and complex renal metabolic dysfunction, resulting in both ketoacidosis and hyperchloremic acidosis. We report a rare case of fatal empagliflozin-associated acidosis with profound hyperchlorem …
The mechanisms are not fully understood but involve increased ketogenesis and complex renal metabolic dysfunction, resulting in both ketoaci …
Association of Familial Hyperkalemia and Hypertension with Proximal Renal Tubular Acidosis and Epileptic Seizures.
Shirin N, Rabinowitz G, Blatt I, Karlish SJD, Farfel Z, Mayan H. Shirin N, et al. Nephron. 2024;148(3):179-184. doi: 10.1159/000531868. Epub 2023 Sep 4. Nephron. 2024. PMID: 37666233
INTRODUCTION: Familial hyperkalemic hypertension (FHHt) is an inherited disease characterized by hyperkalemia, hypertension, and hyperchloremic acidosis (HCA). The primary defect is a hyperactive sodium chloride co-transporter, expressed in the renal distal tubule. …
INTRODUCTION: Familial hyperkalemic hypertension (FHHt) is an inherited disease characterized by hyperkalemia, hypertension, and hyperchl …
Hyperchloremic acidosis is associated with acute kidney injury after abdominal surgery.
Toyonaga Y, Kikura M. Toyonaga Y, et al. Nephrology (Carlton). 2017 Sep;22(9):720-727. doi: 10.1111/nep.12840. Nephrology (Carlton). 2017. PMID: 27312130
AIM: Hyperchloremic acidosis may have an important role as a precursor of acute kidney injury (AKI) in the hyperchloremic environment induced by chloride-rich fluids, but this remains unclear. We tested the hypothesis that hyperchloremic acidosis asses …
AIM: Hyperchloremic acidosis may have an important role as a precursor of acute kidney injury (AKI) in the hyperchloremic envi …
Hyperchloremic acidosis develops at the stage G4 and shifts to high anion gap acidosis at the stage G5 in chronic kidney disease.
Tanemoto M, Kamachi R, Kimura T, Yamada S, Yokoyama T, Okazaki Y. Tanemoto M, et al. Clin Exp Nephrol. 2020 Dec;24(12):1140-1143. doi: 10.1007/s10157-020-01949-x. Epub 2020 Aug 9. Clin Exp Nephrol. 2020. PMID: 32772208
BACKGROUND: Amelioration of hyperchloremic acidosis (Cl-Ac), a common complication in chronic kidney disease (CKD), could preserve renal function in chronic kidney disease (CKD). ...
BACKGROUND: Amelioration of hyperchloremic acidosis (Cl-Ac), a common complication in chronic kidney disease (CKD), could pres …
Metabolic Acidosis Assessment in High-Risk Surgeries: Prognostic Importance.
Silva JM Jr, Ribas Rosa de Oliveira AM, Mendes Nogueira FA, Vianna PM, Amendola CP, Carvalho Carmona MJ, Sá Malbouisson LM. Silva JM Jr, et al. Anesth Analg. 2016 Nov;123(5):1163-1171. doi: 10.1213/ANE.0000000000001575. Anesth Analg. 2016. PMID: 27644062
A Cox regression model for postoperative 30-day mortality showed: in hyperlactatemic acidosis, hazard ratio (HR) = 1.74, 95% confidence interval (CI) = 1.02-2.96; increased anion gap acidosis, HR = 1.68, 95% CI = 0.85-3.81; hyperchloremic acidosis, HR = 1.47, 95% CI …
A Cox regression model for postoperative 30-day mortality showed: in hyperlactatemic acidosis, hazard ratio (HR) = 1.74, 95% confidence inte …
Treatment of refractory and superrefractory status epilepticus with topiramate: A cohort study of 106 patients and a review of the literature.
Fechner A, Hubert K, Jahnke K, Knake S, Konczalla J, Menzler K, Ronellenfitsch MW, Rosenow F, Strzelczyk A. Fechner A, et al. Epilepsia. 2019 Dec;60(12):2448-2458. doi: 10.1111/epi.16382. Epub 2019 Nov 11. Epilepsia. 2019. PMID: 31713232 Review.
Treatment-emergent adverse events were attributed to TPM usage in two patients, one each with pancreatitis and hyperchloremic acidosis, and in 38 patients (35.8%), hyperammonemia was seen. ...
Treatment-emergent adverse events were attributed to TPM usage in two patients, one each with pancreatitis and hyperchloremic acid …
Base deficit does not predict mortality when secondary to hyperchloremic acidosis.
Brill SA, Stewart TR, Brundage SI, Schreiber MA. Brill SA, et al. Shock. 2002 Jun;17(6):459-62. doi: 10.1097/00024382-200206000-00003. Shock. 2002. PMID: 12069180
Thirty-seven patients (49.3%) had hyperchloremic acidosis. Thirty-three patients (46.7%) had lactic acidosis. ...Hyperchloremic acidosis is a common etiology of base deficit in the surgical intensive care unit. ...
Thirty-seven patients (49.3%) had hyperchloremic acidosis. Thirty-three patients (46.7%) had lactic acidosis. ...Hyperchlor …
40 results