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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1991 1
1993 3
1994 2
1995 4
1996 8
1997 7
1998 22
1999 36
2000 42
2001 64
2002 59
2003 72
2004 72
2005 81
2006 80
2007 63
2008 55
2009 39
2010 45
2011 44
2012 55
2013 64
2014 63
2015 63
2016 64
2017 58
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2019 72
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2022 45
2023 40
2024 10

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1,373 results

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Page 1
Hyperhomocysteinemia and cardiovascular diseases.
Guieu R, Ruf J, Mottola G. Guieu R, et al. Ann Biol Clin (Paris). 2022 Feb 1;80(1):7-14. doi: 10.1684/abc.2021.1694. Ann Biol Clin (Paris). 2022. PMID: 35129442 Review.
Hcy is present in plasma, with normal levels between 5 and 15 mumol/L, a slightly elevated level between 15 to 30 mumol/L, moderate from 30 to 100 mumol/L and a value > 100 mumol/L classified as severe hyperhomocysteinemia (HHcy). HHcy has been associated with inflammat …
Hcy is present in plasma, with normal levels between 5 and 15 mumol/L, a slightly elevated level between 15 to 30 mumol/L, moderate from 30 …
Causes of hyperhomocysteinemia and its pathological significance.
Kim J, Kim H, Roh H, Kwon Y. Kim J, et al. Arch Pharm Res. 2018 Apr;41(4):372-383. doi: 10.1007/s12272-018-1016-4. Epub 2018 Mar 19. Arch Pharm Res. 2018. PMID: 29552692 Review.
Homocysteine is biosynthesized from methionine through multiple steps and then goes through one of two major metabolic pathways: remethylation and transsulfuration. Hyperhomocysteinemia is a state in which too much homocysteine is present in the body. The main cause of …
Homocysteine is biosynthesized from methionine through multiple steps and then goes through one of two major metabolic pathways: remethylati …
Hyperhomocysteinemia in Cardiovascular Diseases: Revisiting Observational Studies and Clinical Trials.
Guéant JL, Guéant-Rodriguez RM, Oussalah A, Zuily S, Rosenberg I. Guéant JL, et al. Thromb Haemost. 2023 Mar;123(3):270-282. doi: 10.1055/a-1952-1946. Epub 2022 Sep 28. Thromb Haemost. 2023. PMID: 36170884 Free article. Review.
In contrast, moderate hyperhomocysteinemia (15-30 mol/L) is a modest predictor of cardiovascular risk. ...Further trials are needed to assess the effect of lowering homocysteine according to hyperhomocysteinemia categories at baseline....
In contrast, moderate hyperhomocysteinemia (15-30 mol/L) is a modest predictor of cardiovascular risk. ...Further trials are needed t …
ACMG Practice Guideline: lack of evidence for MTHFR polymorphism testing.
Hickey SE, Curry CJ, Toriello HV. Hickey SE, et al. Genet Med. 2013 Feb;15(2):153-6. doi: 10.1038/gim.2012.165. Epub 2013 Jan 3. Genet Med. 2013. PMID: 23288205 Free article.
It was previously hypothesized that reduced enzyme activity of MTHFR led to mild hyperhomocysteinemia which led to an increased risk for venous thromboembolism, coronary heart disease, and recurrent pregnancy loss. Recent meta-analyses have disproven an association between …
It was previously hypothesized that reduced enzyme activity of MTHFR led to mild hyperhomocysteinemia which led to an increased risk …
The relationship between hyperhomocysteinemia and neurodegeneration.
Bonetti F, Brombo G, Zuliani G. Bonetti F, et al. Neurodegener Dis Manag. 2016 Apr;6(2):133-45. doi: 10.2217/nmt-2015-0008. Epub 2016 Apr 1. Neurodegener Dis Manag. 2016. PMID: 27033101 Review.
Homocysteine (Hcy) is a key junction in methionine metabolism. In inherited forms of hyperhomocysteinemia patients develop early vascular damage and cognitive decline. Hyperhomocysteinemia is a common consequence of dietary, behavioral and pathological conditions an …
Homocysteine (Hcy) is a key junction in methionine metabolism. In inherited forms of hyperhomocysteinemia patients develop early vasc …
Venous and Arterial Thrombosis: Is There a Link?
Prandoni P. Prandoni P. Adv Exp Med Biol. 2017;906:273-283. doi: 10.1007/5584_2016_121. Adv Exp Med Biol. 2017. PMID: 27628000 Review.
Moreover, there are many examples of conditions accounting for both venous and arterial thrombosis, such as the antiphospholipid antibody syndrome, hyperhomocysteinemia, malignancies, infections, and the use of hormonal treatment. ...
Moreover, there are many examples of conditions accounting for both venous and arterial thrombosis, such as the antiphospholipid antibody sy …
Hyperhomocysteinemia, atherosclerosis and thrombosis.
Cattaneo M. Cattaneo M. Thromb Haemost. 1999 Feb;81(2):165-76. Thromb Haemost. 1999. PMID: 10063987 Review.
In the last two decades, a growing amount of interest has focused on mild-to-moderate hyperhomocysteinemia as a risk factor of thromboembolic diseases. Case-control and cross-sectional studies clearly indicated that mild-to-moderate hyperhomocysteinemia is associate …
In the last two decades, a growing amount of interest has focused on mild-to-moderate hyperhomocysteinemia as a risk factor of thromb …
Diagnosis and treatment of hyperhomocysteinemia.
Keebler ME, De Souza C, Fonseca V. Keebler ME, et al. Curr Atheroscler Rep. 2001 Jan;3(1):54-63. doi: 10.1007/s11883-001-0011-1. Curr Atheroscler Rep. 2001. PMID: 11123849 Review.
Hyperhomocysteinemia has emerged as an important risk factor for cardiovascular disease. ...
Hyperhomocysteinemia has emerged as an important risk factor for cardiovascular disease. ...
Hyperhomocysteinemia in Adult Patients: A Treatable Metabolic Condition.
González-Lamuño D, Arrieta-Blanco FJ, Fuentes ED, Forga-Visa MT, Morales-Conejo M, Peña-Quintana L, Vitoria-Miñana I. González-Lamuño D, et al. Nutrients. 2023 Dec 30;16(1):135. doi: 10.3390/nu16010135. Nutrients. 2023. PMID: 38201964 Free PMC article. Review.
Hyperhomocysteinemia (HHcy) is recognized as an independent risk factor for various significant medical conditions, yet controversy persists around its assessment and management. ...
Hyperhomocysteinemia (HHcy) is recognized as an independent risk factor for various significant medical conditions, yet controversy p
Homocysteine and Non-Cardiac Vascular Disease.
Katsiki N, Perez-Martinez P, Mikhailidis DP. Katsiki N, et al. Curr Pharm Des. 2017;23(22):3224-3232. doi: 10.2174/1381612823666170317124913. Curr Pharm Des. 2017. PMID: 28317478 Review.
Elevated homocysteine (Hcy) levels are predictors of cardiovascular disease (CVD). Hyperhomocysteinemia has also been associated with total and CVD mortality. ...
Elevated homocysteine (Hcy) levels are predictors of cardiovascular disease (CVD). Hyperhomocysteinemia has also been associated with …
1,373 results