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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1970 1
1975 1
1980 1
1981 1
1987 3
1988 1
1990 1
1991 3
1992 1
1993 2
1994 3
1995 1
1996 2
1997 3
1998 2
1999 1
2000 2
2001 3
2002 4
2003 8
2004 5
2005 6
2006 9
2007 7
2008 5
2009 7
2010 8
2011 7
2012 11
2013 9
2014 11
2015 22
2016 24
2017 28
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2020 27
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2023 29
2024 10

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328 results

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Page 1
Lactic Acidosis in Sepsis: It's Not All Anaerobic: Implications for Diagnosis and Management.
Suetrong B, Walley KR. Suetrong B, et al. Chest. 2016 Jan;149(1):252-61. doi: 10.1378/chest.15-1703. Epub 2016 Jan 6. Chest. 2016. PMID: 26378980 Review.
Increased blood lactate concentration (hyperlactatemia) and lactic acidosis (hyperlactatemia and serum pH < 7.35) are common in patients with severe sepsis or septic shock and are associated with significant morbidity and mortality. ...

Increased blood lactate concentration (hyperlactatemia) and lactic acidosis (hyperlactatemia and serum pH < 7.35) are commo

…
Lactic acidosis.
Kraut JA, Madias NE. Kraut JA, et al. N Engl J Med. 2014 Dec 11;371(24):2309-19. doi: 10.1056/NEJMra1309483. N Engl J Med. 2014. PMID: 25494270 Review. No abstract available.
Comprehensive review on lactate metabolism in human health.
Adeva-Andany M, López-Ojén M, Funcasta-Calderón R, Ameneiros-Rodríguez E, Donapetry-García C, Vila-Altesor M, Rodríguez-Seijas J. Adeva-Andany M, et al. Mitochondrion. 2014 Jul;17:76-100. doi: 10.1016/j.mito.2014.05.007. Epub 2014 Jun 12. Mitochondrion. 2014. PMID: 24929216 Review.
Both obese individuals and patients with diabetes show elevated plasma lactate concentration compared to healthy subjects, but there is no conclusive evidence of hyperlactatemia causing insulin resistance. Available evidence suggests an association between defective mitoch …
Both obese individuals and patients with diabetes show elevated plasma lactate concentration compared to healthy subjects, but there is no c …
What Is the Utility of Measuring Lactate Levels in Patients with Sepsis and Septic Shock?
Weinberger J, Klompas M, Rhee C. Weinberger J, et al. Semin Respir Crit Care Med. 2021 Oct;42(5):650-661. doi: 10.1055/s-0041-1733915. Epub 2021 Sep 20. Semin Respir Crit Care Med. 2021. PMID: 34544182 Review.
Lactate is not specific to infection and its frequent use for sepsis screening and diagnosis may therefore trigger unnecessary broad-spectrum antibiotic use in some patients. Because hyperlactatemia does not always reflect fluid-responsive hypoperfusion, titrating resuscit …
Lactate is not specific to infection and its frequent use for sepsis screening and diagnosis may therefore trigger unnecessary broad-spectru …
Medication-Induced Hyperlactatemia and Lactic Acidosis: A Systematic Review of the Literature.
Smith ZR, Horng M, Rech MA. Smith ZR, et al. Pharmacotherapy. 2019 Sep;39(9):946-963. doi: 10.1002/phar.2316. Epub 2019 Aug 29. Pharmacotherapy. 2019. PMID: 31361914
Hyperlactatemia and lactic acidosis are two syndromes that are associated with morbidity and mortality. Medication-induced hyperlactatemia and lactic acidosis are diagnoses of exclusion and have the potential to be overlooked. ...
Hyperlactatemia and lactic acidosis are two syndromes that are associated with morbidity and mortality. Medication-induced hyperla …
Drug-induced hyperlactatemia.
Blohm E, Lai J, Neavyn M. Blohm E, et al. Clin Toxicol (Phila). 2017 Sep;55(8):869-878. doi: 10.1080/15563650.2017.1317348. Epub 2017 Apr 27. Clin Toxicol (Phila). 2017. PMID: 28447886 Review.
BACKGROUND: Hyperlactatemia is common in critically ill patients and has a variety of etiologies. ...CONCLUSIONS: Hyperlactatemia is a relatively rare but life-threatening toxicity of various medication classes. ...
BACKGROUND: Hyperlactatemia is common in critically ill patients and has a variety of etiologies. ...CONCLUSIONS: Hyperlactatemia …
Hyperlactatemia and Cardiac Surgery.
Minton J, Sidebotham DA. Minton J, et al. J Extra Corpor Technol. 2017 Mar;49(1):7-15. J Extra Corpor Technol. 2017. PMID: 28298660 Free PMC article. Review.
The normal blood lactate level is 0-2 mmol/L, and a value above 3-5 mmol/L is variably used to define hyperlactatemia. In cardiac surgical patients, hyperlactatemia can arise from both hypoxic and non-hypoxic mechanisms. ...The mechanism of late onset hyperlactat …
The normal blood lactate level is 0-2 mmol/L, and a value above 3-5 mmol/L is variably used to define hyperlactatemia. In cardiac sur …
A targeted real-time early warning score (TREWScore) for septic shock.
Henry KE, Hager DN, Pronovost PJ, Saria S. Henry KE, et al. Sci Transl Med. 2015 Aug 5;7(299):299ra122. doi: 10.1126/scitranslmed.aab3719. Sci Transl Med. 2015. PMID: 26246167
A routine screening protocol based on the presence of two of the systemic inflammatory response syndrome criteria, suspicion of infection, and either hypotension or hyperlactatemia achieved a lower sensitivity of 0.74 at a comparable specificity of 0.64. ...
A routine screening protocol based on the presence of two of the systemic inflammatory response syndrome criteria, suspicion of infection, a …
Sepsis-associated hyperlactatemia.
Garcia-Alvarez M, Marik P, Bellomo R. Garcia-Alvarez M, et al. Crit Care. 2014 Sep 9;18(5):503. doi: 10.1186/s13054-014-0503-3. Crit Care. 2014. PMID: 25394679 Free PMC article. Review.
There is overwhelming evidence that sepsis and septic shock are associated with hyperlactatemia (sepsis-associated hyperlactatemia (SAHL)). SAHL is a strong independent predictor of mortality and its presence and progression are widely appreciated by clinicians to d …
There is overwhelming evidence that sepsis and septic shock are associated with hyperlactatemia (sepsis-associated hyperlactatemia …
Update: Clinical Use of Plasma Lactate.
Gillespie Í, Rosenstein PG, Hughes D. Gillespie Í, et al. Vet Clin North Am Small Anim Pract. 2017 Mar;47(2):325-342. doi: 10.1016/j.cvsm.2016.10.011. Epub 2016 Dec 1. Vet Clin North Am Small Anim Pract. 2017. PMID: 27914760 Review.
Lactate production is a protective response providing ongoing cellular energy during tissue hypoperfusion or hypoxia and mitigating acidosis. Hence, hyperlactatemia is closely associated with disease severity but it is an epiphenomenon as the body attempts to protect itsel …
Lactate production is a protective response providing ongoing cellular energy during tissue hypoperfusion or hypoxia and mitigating acidosis …
328 results