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Year Number of Results
1978 1
1981 1
1984 1
1985 2
1987 1
1988 1
1990 1
1992 1
1993 1
1994 2
1995 4
1996 3
1997 6
1998 4
1999 2
2000 5
2001 5
2002 3
2003 15
2004 13
2005 8
2006 13
2007 10
2008 8
2009 8
2010 15
2011 14
2012 15
2013 16
2014 12
2015 28
2016 26
2017 51
2018 34
2019 31
2020 34
2021 45
2022 43
2023 37
2024 13

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467 results

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Page 1
Epinephrine Versus Norepinephrine for Cardiogenic Shock After Acute Myocardial Infarction.
Levy B, Clere-Jehl R, Legras A, Morichau-Beauchant T, Leone M, Frederique G, Quenot JP, Kimmoun A, Cariou A, Lassus J, Harjola VP, Meziani F, Louis G, Rossignol P, Duarte K, Girerd N, Mebazaa A, Vignon P; Collaborators. Levy B, et al. J Am Coll Cardiol. 2018 Jul 10;72(2):173-182. doi: 10.1016/j.jacc.2018.04.051. J Am Coll Cardiol. 2018. PMID: 29976291 Free article. Clinical Trial.
Refractory CS was defined as CS with sustained hypotension, end-organ hypoperfusion and hyperlactatemia, and high inotrope and vasopressor doses. RESULTS: Fifty-seven patients were randomized into 2 study arms, epinephrine and norepinephrine. ...
Refractory CS was defined as CS with sustained hypotension, end-organ hypoperfusion and hyperlactatemia, and high inotrope and vasopr …
Glycogen storage diseases: new perspectives.
Ozen H. Ozen H. World J Gastroenterol. 2007 May 14;13(18):2541-53. doi: 10.3748/wjg.v13.i18.2541. World J Gastroenterol. 2007. PMID: 17552001 Free PMC article. Review.
Type Ia involves the liver, kidney and intestine (and Ib also leukocytes), and the clinical manifestations are hepatomegaly, failure to thrive, hypoglycemia, hyperlactatemia, hyperuricemia and hyperlipidemia. Type IIIa involves both the liver and muscle, and IIIb solely th …
Type Ia involves the liver, kidney and intestine (and Ib also leukocytes), and the clinical manifestations are hepatomegaly, failure to thri …
Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.
PRISM Investigators; Rowan KM, Angus DC, Bailey M, Barnato AE, Bellomo R, Canter RR, Coats TJ, Delaney A, Gimbel E, Grieve RD, Harrison DA, Higgins AM, Howe B, Huang DT, Kellum JA, Mouncey PR, Music E, Peake SL, Pike F, Reade MC, Sadique MZ, Singer M, Yealy DM. PRISM Investigators, et al. N Engl J Med. 2017 Jun 8;376(23):2223-2234. doi: 10.1056/NEJMoa1701380. Epub 2017 Mar 21. N Engl J Med. 2017. PMID: 28320242 Free article.
Subgroup analyses showed no benefit from EGDT for patients with worse shock (higher serum lactate level, combined hypotension and hyperlactatemia, or higher predicted risk of death) or for hospitals with a lower propensity to use vasopressors or fluids during usual resusci …
Subgroup analyses showed no benefit from EGDT for patients with worse shock (higher serum lactate level, combined hypotension and hyperla …
Drug-induced hyperlactatemia.
Blohm E, Lai J, Neavyn M. Blohm E, et al. Clin Toxicol (Phila). 2017 Sep;55(8):869-878. doi: 10.1080/15563650.2017.1317348. Epub 2017 Apr 27. Clin Toxicol (Phila). 2017. PMID: 28447886 Review.
BACKGROUND: Hyperlactatemia is common in critically ill patients and has a variety of etiologies. ...CONCLUSIONS: Hyperlactatemia is a relatively rare but life-threatening toxicity of various medication classes. ...
BACKGROUND: Hyperlactatemia is common in critically ill patients and has a variety of etiologies. ...CONCLUSIONS: Hyperlactatemia …
A targeted real-time early warning score (TREWScore) for septic shock.
Henry KE, Hager DN, Pronovost PJ, Saria S. Henry KE, et al. Sci Transl Med. 2015 Aug 5;7(299):299ra122. doi: 10.1126/scitranslmed.aab3719. Sci Transl Med. 2015. PMID: 26246167
A routine screening protocol based on the presence of two of the systemic inflammatory response syndrome criteria, suspicion of infection, and either hypotension or hyperlactatemia achieved a lower sensitivity of 0.74 at a comparable specificity of 0.64. ...
A routine screening protocol based on the presence of two of the systemic inflammatory response syndrome criteria, suspicion of infection, a …
Comparison of 5% human albumin and normal saline for fluid resuscitation in sepsis induced hypotension among patients with cirrhosis (FRISC study): a randomized controlled trial.
Philips CA, Maiwall R, Sharma MK, Jindal A, Choudhury AK, Kumar G, Bhardwaj A, Mitra LG, Agarwal PM, Sarin SK. Philips CA, et al. Hepatol Int. 2021 Aug;15(4):983-994. doi: 10.1007/s12072-021-10164-z. Epub 2021 May 25. Hepatol Int. 2021. PMID: 34036519 Clinical Trial.
Reversal of hypotension was higher in patients receiving 5% albumin than saline at the end of one hour [25.3% and 11.7%, p = 0.03, Odds ratio (95% CI)-1.9 (1.08-3.42)] and at the end of three hours [11.7% and 3.2%, p = 0.008, 3.9 (1.42-10.9)]. Sustained reduction in heart rate an …
Reversal of hypotension was higher in patients receiving 5% albumin than saline at the end of one hour [25.3% and 11.7%, p = 0.03, Odds rati …
Sepsis-associated hyperlactatemia.
Garcia-Alvarez M, Marik P, Bellomo R. Garcia-Alvarez M, et al. Crit Care. 2014 Sep 9;18(5):503. doi: 10.1186/s13054-014-0503-3. Crit Care. 2014. PMID: 25394679 Free PMC article. Review.
There is overwhelming evidence that sepsis and septic shock are associated with hyperlactatemia (sepsis-associated hyperlactatemia (SAHL)). SAHL is a strong independent predictor of mortality and its presence and progression are widely appreciated by clinicians to d …
There is overwhelming evidence that sepsis and septic shock are associated with hyperlactatemia (sepsis-associated hyperlactatemia …
Hyperlactatemia in diabetic ketoacidosis.
Masharani U, Strycker LA, Lazar AA, Wu K, Brooks GA. Masharani U, et al. Diabet Med. 2022 Apr;39(4):e14723. doi: 10.1111/dme.14723. Epub 2021 Oct 22. Diabet Med. 2022. PMID: 34655270
Advances in acute asthma.
Rodrigo GJ. Rodrigo GJ. Curr Opin Pulm Med. 2015 Jan;21(1):22-6. doi: 10.1097/MCP.0000000000000123. Curr Opin Pulm Med. 2015. PMID: 25405669 Review.
Other findings indicate that there is no robust evidence to support the use of intravenous or nebulized magnesium sulphate in adults with severe acute asthma, and that levalbuterol was not superior to albuterol regarding efficacy and safety in individuals with acute asthma. Final …
Other findings indicate that there is no robust evidence to support the use of intravenous or nebulized magnesium sulphate in adults with se …
Intestinal injury in paracetamol overdose (ATOM-8).
Perananthan V, Shihana F, Chiew AL, George J, Dawson A, Buckley NA. Perananthan V, et al. J Gastroenterol Hepatol. 2024 May;39(5):920-926. doi: 10.1111/jgh.16450. Epub 2023 Dec 27. J Gastroenterol Hepatol. 2024. PMID: 38149309

RESULTS: In paracetamol overdose patients, median plasma IFABP was significantly elevated compared with healthy controls (720 mug/L [interquartile range, IQR, 533-1644] vs 270 mug/L [IQR 153-558], P < 0.001). Four patients had early hyperlactatemia and had significantly

…
RESULTS: In paracetamol overdose patients, median plasma IFABP was significantly elevated compared with healthy controls (720 mug/L [interqu …
467 results