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Page 1
Medication-Induced Hyperlactatemia and Lactic Acidosis: A Systematic Review of the Literature.
Smith ZR, Horng M, Rech MA. Smith ZR, et al. Pharmacotherapy. 2019 Sep;39(9):946-963. doi: 10.1002/phar.2316. Epub 2019 Aug 29. Pharmacotherapy. 2019. PMID: 31361914
Hyperlactatemia and lactic acidosis are two syndromes that are associated with morbidity and mortality. Medication-induced hyperlactatemia and lactic acidosis are diagnoses of exclusion and have the potential to be overlooked. ...
Hyperlactatemia and lactic acidosis are two syndromes that are associated with morbidity and mortality. Medication-induced hyperla …
Metformin's Role in Hyperlactatemia and Lactic Acidosis in ICU Patients: A Systematic Review.
Mueller L, Moser M, Prazak J, Fuster DG, Schefold JC, Zuercher P. Mueller L, et al. Pharmacology. 2023;108(3):213-223. doi: 10.1159/000528252. Epub 2023 Jan 18. Pharmacology. 2023. PMID: 36652938 Free PMC article.
INTRODUCTION: Metformin-treated patients may experience severe hyperlactatemia or lactic acidosis (LA). LA often requires intensive-care-unit (ICU) treatment, and mortality rates are high. ...METHODS: We performed a retrospective analysis based on a systematic PubMed searc …
INTRODUCTION: Metformin-treated patients may experience severe hyperlactatemia or lactic acidosis (LA). LA often requires intensive-c …
A systematic review and diagnostic test accuracy meta-analysis of the validity of anion gap as a screening tool for hyperlactatemia.
Glasmacher SA, Stones W. Glasmacher SA, et al. BMC Res Notes. 2017 Nov 3;10(1):556. doi: 10.1186/s13104-017-2853-9. BMC Res Notes. 2017. PMID: 29100545 Free PMC article. Review.
RESULTS: Nine studies reporting on 4504 samples from 2111 patients were included. The anion gap failed to detect hyperlactatemia defined as lactate above 2.5 mmol/l but showed good discriminatory ability for the detection of severe hyperlactatemia defined as lactate …
RESULTS: Nine studies reporting on 4504 samples from 2111 patients were included. The anion gap failed to detect hyperlactatemia defi …
Blood lactate concentration in COVID-19: a systematic literature review.
Carpenè G, Onorato D, Nocini R, Fortunato G, Rizk JG, Henry BM, Lippi G. Carpenè G, et al. Clin Chem Lab Med. 2021 Dec 2;60(3):332-337. doi: 10.1515/cclm-2021-1115. Print 2022 Feb 23. Clin Chem Lab Med. 2021. PMID: 34856090 Free article.
We carried out an electronic search in Medline and Scopus, using the keywords "COVID-19" OR "SARS-CoV-2" AND "lactate" OR "lactic acid" OR "hyperlactatemia", between 2019 and present time (i.e. October 10, 2021), which allowed to identify 19 studies, totalling 6,459 patien …
We carried out an electronic search in Medline and Scopus, using the keywords "COVID-19" OR "SARS-CoV-2" AND "lactate" OR "lactic acid" OR " …
Low dose versus high dose stavudine for treating people with HIV infection.
Magula N, Dedicoat M. Magula N, et al. Cochrane Database Syst Rev. 2015 Jan 28;1(1):CD007497. doi: 10.1002/14651858.CD007497.pub2. Cochrane Database Syst Rev. 2015. PMID: 25627012 Free PMC article. Review.
There was no significant difference in virologic suppression in the included studies (Milinkovic 2007; McComsey 2008; Sanchez-Conde 2005); Risk Ratio (RR) 1.09 (95% CI: 0.93 to 1.28), 0.94 (95% CI:0.59 to 1.50) and 1.03 (95% CI: 0.90 to 1.18) respectively. Symptomatic hyperlac …
There was no significant difference in virologic suppression in the included studies (Milinkovic 2007; McComsey 2008; Sanchez-Conde 2005); R …
Pathogenicity Analysis of a Novel Variant in GTPBP3 Causing Mitochondrial Disease and Systematic Literature Review.
Zhang Q, Ouyang Q, Xiang J, Li H, Lv H, An Y. Zhang Q, et al. Genes (Basel). 2023 Feb 22;14(3):552. doi: 10.3390/genes14030552. Genes (Basel). 2023. PMID: 36980825 Free PMC article.
Here, we reported a 9-year-old boy with COXPD23 who presented with hyperlactatemia, hypertrophic cardiomyopathy, seizures, feeding difficulties, intellectual disability and motor developmental delay, and abnormal visual development. ...We curated 18 COXPD23 patients with G …
Here, we reported a 9-year-old boy with COXPD23 who presented with hyperlactatemia, hypertrophic cardiomyopathy, seizures, feeding di …
Early lactate area scores and serial blood lactate levels as prognostic markers for patients with septic shock: a systematic review.
Khodashahi R, Sarjamee S. Khodashahi R, et al. Infect Dis (Lond). 2020 Jul;52(7):451-463. doi: 10.1080/23744235.2020.1749298. Epub 2020 Apr 17. Infect Dis (Lond). 2020. PMID: 32301359
The lactate area is a new concept introduced as the sum of the AUC of serial lactate levels. This factor can determine the severity and duration of hyperlactatemia. Based on the obtained results, there was an association between the lactate area score and 28-day mortality …
The lactate area is a new concept introduced as the sum of the AUC of serial lactate levels. This factor can determine the severity and dura …
Agreement between arterial and peripheral venous lactate levels in the ED: A systematic review.
van Tienhoven AJ, van Beers CAJ, Siegert CEH. van Tienhoven AJ, et al. Am J Emerg Med. 2019 Apr;37(4):746-750. doi: 10.1016/j.ajem.2019.01.034. Epub 2019 Jan 21. Am J Emerg Med. 2019. PMID: 30686538
Peripheral venous lactate levels tend to be higher than arterial lactate levels with mean differences ranging from 0.18 mmol/l to 1.06 mmol/l. Importantly, poorer agreement occurs in hyperlactatemia. At a cut-of level of 1.6 mmol/l, peripheral venous lactate can rule out a …
Peripheral venous lactate levels tend to be higher than arterial lactate levels with mean differences ranging from 0.18 mmol/l to 1.06 mmol/ …
Risk Factors for Adverse Outcomes in Adult and Pediatric Patients With Hyperglycemia Presenting to the Emergency Department: A Systematic Review.
Siddiqi L, VanAarsen K, Iansavichene A, Yan J. Siddiqi L, et al. Can J Diabetes. 2019 Jul;43(5):361-369.e2. doi: 10.1016/j.jcjd.2018.11.008. Epub 2018 Dec 6. Can J Diabetes. 2019. PMID: 30846250
Predictors of adverse outcomes included age, lowest income quintile, urban dwellers, presence of comorbidities, coexisting hyperlactatemia, having a family physician, elevated serum creatinine level, diabetes managed with insulin, sentinel visit for hyperglycemia in the pa …
Predictors of adverse outcomes included age, lowest income quintile, urban dwellers, presence of comorbidities, coexisting hyperlactatemi …