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Quoted phrase not found in phrase index: "Hypertriglyceridemia 2"
Page 1
The Diagnosis and Treatment of Hypertriglyceridemia.
Parhofer KG, Laufs U. Parhofer KG, et al. Dtsch Arztebl Int. 2019 Dec 6;116(49):825-832. doi: 10.3238/arztebl.2019.0825. Dtsch Arztebl Int. 2019. PMID: 31888796 Free PMC article. Review.
BACKGROUND: Hypertriglyceridemia affects 15-20% of the adult population and is associated with overweight, metabolic syndrome, and diabetes mellitus. ...CONCLUSION: Hypertriglyceridemia is causally linked to cardiovascular disease and pancreatitis. ...
BACKGROUND: Hypertriglyceridemia affects 15-20% of the adult population and is associated with overweight, metabolic syndrome, and di …
Clinical Management of Hypertriglyceridemia in the Prevention of Cardiovascular Disease and Pancreatitis.
Hernandez P, Passi N, Modarressi T, Kulkarni V, Soni M, Burke F, Bajaj A, Soffer D. Hernandez P, et al. Curr Atheroscler Rep. 2021 Sep 13;23(11):72. doi: 10.1007/s11883-021-00962-z. Curr Atheroscler Rep. 2021. PMID: 34515873 Free PMC article. Review.
PURPOSE OF REVIEW: Hypertriglyceridemia (HTG) is common and is a significant contributor to atherosclerosis and pancreatitis risk. ...In addition, the REDUCE-IT study provides evidence for additional benefit from the use of high-dose icosapent ethyl (IPE) on top of backgro …
PURPOSE OF REVIEW: Hypertriglyceridemia (HTG) is common and is a significant contributor to atherosclerosis and pancreatitis risk. .. …
Triglycerides and cardiovascular disease.
Nordestgaard BG, Varbo A. Nordestgaard BG, et al. Lancet. 2014 Aug 16;384(9943):626-635. doi: 10.1016/S0140-6736(14)61177-6. Lancet. 2014. PMID: 25131982 Review.
Triglycerides can be measured in the non-fasting or fasting states, with concentrations of 2-10 mmol/L conferring increased risk of cardiovascular disease, and concentrations greater than 10 mmol/L conferring increased risk of acute pancreatitis and possibly cardiovascular …
Triglycerides can be measured in the non-fasting or fasting states, with concentrations of 2-10 mmol/L conferring increased risk of c …
The Forgotten Lipids: Triglycerides, Remnant Cholesterol, and Atherosclerotic Cardiovascular Disease Risk.
Sandesara PB, Virani SS, Fazio S, Shapiro MD. Sandesara PB, et al. Endocr Rev. 2019 Apr 1;40(2):537-557. doi: 10.1210/er.2018-00184. Endocr Rev. 2019. PMID: 30312399 Free PMC article. Review.
However, despite substantial reduction in LDL-C, patients continue to have recurrent ASCVD events. Hypertriglyceridemia may be an important contributor of this residual risk. ...Although lifestyle modification remains the cornerstone for management of hypertriglyceridem …
However, despite substantial reduction in LDL-C, patients continue to have recurrent ASCVD events. Hypertriglyceridemia may be an imp …
Updates in Drug Treatment of Severe Hypertriglyceridemia.
Gouni-Berthold I, Schwarz J, Berthold HK. Gouni-Berthold I, et al. Curr Atheroscler Rep. 2023 Oct;25(10):701-709. doi: 10.1007/s11883-023-01140-z. Epub 2023 Aug 29. Curr Atheroscler Rep. 2023. PMID: 37642858 Free PMC article. Review.
PURPOSE OF REVIEW: To provide an insight into the new pharmacological options for the treatment of severe hypertriglyceridemia (sHTG). RECENT FINDINGS: sHTG is difficult to treat. ...Therapeutic options with novel mechanisms of action have been developed, such as antisense …
PURPOSE OF REVIEW: To provide an insight into the new pharmacological options for the treatment of severe hypertriglyceridemia (sHTG) …
Mechanisms linking hypertriglyceridemia to acute pancreatitis.
Kiss L, Fűr G, Pisipati S, Rajalingamgari P, Ewald N, Singh V, Rakonczay Z Jr. Kiss L, et al. Acta Physiol (Oxf). 2023 Mar;237(3):e13916. doi: 10.1111/apha.13916. Epub 2023 Jan 13. Acta Physiol (Oxf). 2023. PMID: 36599412 Review.
Hypertriglyceridemia (HTG) is a metabolic disorder, defined when serum or plasma triglyceride concentration (seTG) is >1.7 mM. ...FAs inhibit mitochondrial complexes in pancreatic acinar cells, induce pathological elevation of intracellular Ca(2+) concentration, …
Hypertriglyceridemia (HTG) is a metabolic disorder, defined when serum or plasma triglyceride concentration (seTG) is >1.7 mM. ... …
Prevention and Management of Hypertriglyceridemia-Induced Acute Pancreatitis During Pregnancy: A Systematic Review.
Gupta M, Liti B, Barrett C, Thompson PD, Fernandez AB. Gupta M, et al. Am J Med. 2022 Jun;135(6):709-714. doi: 10.1016/j.amjmed.2021.12.006. Epub 2022 Jan 23. Am J Med. 2022. PMID: 35081380 Review.
Severe gestational hypertriglyceridemia can lead to acute pancreatitis, with maternal mortality rate of approximately 20%. The recent National Lipid Association part 2 expert panel recommendations provide guidance on monitoring pregnant women at high risk for hyperl …
Severe gestational hypertriglyceridemia can lead to acute pancreatitis, with maternal mortality rate of approximately 20%. The recent …
Triglycerides and Residual Atherosclerotic Risk.
Raposeiras-Roubin S, Rosselló X, Oliva B, Fernández-Friera L, Mendiguren JM, Andrés V, Bueno H, Sanz J, Martínez de Vega V, Abu-Assi E, Iñiguez A, Fernández-Ortiz A, Ibáñez B, Fuster V. Raposeiras-Roubin S, et al. J Am Coll Cardiol. 2021 Jun 22;77(24):3031-3041. doi: 10.1016/j.jacc.2021.04.059. J Am Coll Cardiol. 2021. PMID: 34140107 Free PMC article.
METHODS: An observational, longitudinal, and prospective cohort study, including 3,754 middle-aged individuals with low to moderate cardiovascular risk from the PESA (Progression of Early Subclinical Atherosclerosis) study who were consecutively recruited between June 2010 and Fe …
METHODS: An observational, longitudinal, and prospective cohort study, including 3,754 middle-aged individuals with low to moderate cardiova …
The FGF21 analog pegozafermin in severe hypertriglyceridemia: a randomized phase 2 trial.
Bhatt DL, Bays HE, Miller M, Cain JE 3rd, Wasilewska K, Andrawis NS, Parli T, Feng S, Sterling L, Tseng L, Hartsfield CL, Agollah GD, Mansbach H, Kastelein JJP; ENTRIGUE Principal Investigators. Bhatt DL, et al. Nat Med. 2023 Jul;29(7):1782-1792. doi: 10.1038/s41591-023-02427-z. Epub 2023 Jun 24. Nat Med. 2023. PMID: 37355760 Free PMC article. Clinical Trial.
Pegozafermin, a long-acting glycopegylated analog of human fibroblast growth factor 21, is in development for the treatment of severe hypertriglyceridemia (SHTG) and nonalcoholic steatohepatitis. Here we report the results of a phase 2, double-blind, randomized, fiv …
Pegozafermin, a long-acting glycopegylated analog of human fibroblast growth factor 21, is in development for the treatment of severe hyp …
Triglyceride-Rich Lipoproteins and Atherosclerotic Cardiovascular Disease: New Insights From Epidemiology, Genetics, and Biology.
Nordestgaard BG. Nordestgaard BG. Circ Res. 2016 Feb 19;118(4):547-63. doi: 10.1161/CIRCRESAHA.115.306249. Circ Res. 2016. PMID: 26892957 Review.
New insight in epidemiology now suggests that these lipoproteins, marked by high triglycerides, are strong and independent predictors of ASCVD and all-cause mortality, and that their cholesterol content or remnant cholesterol likewise are strong predictors of ASCVD. Of all adults …
New insight in epidemiology now suggests that these lipoproteins, marked by high triglycerides, are strong and independent predictors of ASC …
4,915 results