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1967 2
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1974 3
1975 7
1976 6
1977 1
1978 2
1979 2
1980 1
1981 4
1982 2
1983 3
1984 3
1985 2
1986 4
1987 6
1988 2
1990 1
1991 2
1992 1
1993 3
1994 1
1995 2
1997 3
1998 2
1999 2
2000 4
2001 3
2002 1
2003 5
2004 4
2006 2
2007 4
2008 2
2009 6
2010 6
2011 6
2012 1
2013 3
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2015 3
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146 results

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Quoted phrase not found in phrase index: "Hypoplasia of the thymus"
Page 1
Thymus transplantation.
Markert ML, Devlin BH, McCarthy EA. Markert ML, et al. Clin Immunol. 2010 May;135(2):236-46. doi: 10.1016/j.clim.2010.02.007. Epub 2010 Mar 16. Clin Immunol. 2010. PMID: 20236866 Free PMC article. Review.
Thymus transplantation is a promising investigational therapy for infants born with no thymus. Because of the athymia, these infants lack T cell development and have a severe primary immunodeficiency. Although thymic hypoplasia or aplasia is characteristic of …
Thymus transplantation is a promising investigational therapy for infants born with no thymus. Because of the athymia, these i …
Histiocytosis-X.
Osband ME, Lipton JM, Lavin P, Levey R, Vawter G, Greenberger JS, McCaffrey RP, Parkman R. Osband ME, et al. N Engl J Med. 1981 Jan 15;304(3):146-53. doi: 10.1056/NEJM198101153040304. N Engl J Med. 1981. PMID: 6449667 Clinical Trial.
The patients also had a notable lack of histamine H2 surface receptors on their T lymphocytes, suggesting a suppressor-cell deficiency. The lymphocyte abnormalities were reversed in vitro after incubation in a crude extract of calf thymus gland, and therefore …
The patients also had a notable lack of histamine H2 surface receptors on their T lymphocytes, suggesting a suppressor-cell deficiency. The …
The consequences of not having eosinophils.
Gleich GJ, Klion AD, Lee JJ, Weller PF. Gleich GJ, et al. Allergy. 2013 Jul;68(7):829-35. doi: 10.1111/all.12169. Epub 2013 Jun 6. Allergy. 2013. PMID: 23742015 Free PMC article. Review.
Patients lacking eosinophils, in the setting of immunodeficiency or as a consequence of IgG-mediated eosinophil precursor destruction, do not display any distinguishing abnormalities related to eosinophil reduction. The observation that eosinophil-deficient mice do not dis …
Patients lacking eosinophils, in the setting of immunodeficiency or as a consequence of IgG-mediated eosinophil precursor destruction, do no …
Vitamin D and multiple sclerosis: An update.
Pierrot-Deseilligny C, Souberbielle JC. Pierrot-Deseilligny C, et al. Mult Scler Relat Disord. 2017 May;14:35-45. doi: 10.1016/j.msard.2017.03.014. Epub 2017 Mar 29. Mult Scler Relat Disord. 2017. PMID: 28619429 Review.
Moreover, several large genetic studies in MS patients have recently stated unequivocally that diverse abnormalities involving vitamin D metabolism are related to the risk of the disease. ...However, there is still an enduring absence of major conclusive randomized …
Moreover, several large genetic studies in MS patients have recently stated unequivocally that diverse abnormalities involving vitami …
Current and Future Therapeutic Approaches for Thymic Stromal Cell Defects.
Kreins AY, Bonfanti P, Davies EG. Kreins AY, et al. Front Immunol. 2021 Mar 18;12:655354. doi: 10.3389/fimmu.2021.655354. eCollection 2021. Front Immunol. 2021. PMID: 33815417 Free PMC article. Review.
This group of disorders cannot be corrected by hematopoietic stem cell transplantation, but upon timely recognition as thymic defects, can successfully be treated by thymus transplantation using cultured postnatal thymic tissue with the generation of naive T-cells showing …
This group of disorders cannot be corrected by hematopoietic stem cell transplantation, but upon timely recognition as thymic defects, can s …
Care of Children with DiGeorge Before and After Cultured Thymus Tissue Implantation.
Gupton SE, McCarthy EA, Markert ML. Gupton SE, et al. J Clin Immunol. 2021 Jul;41(5):896-905. doi: 10.1007/s10875-021-01044-0. Epub 2021 May 18. J Clin Immunol. 2021. PMID: 34003433 Free PMC article.
BACKGROUND: Children with complete DiGeorge anomaly (cDGA) have congenital athymia plus a myriad of other challenging clinical conditions. The term cDGA encompasses children with congenital athymia secondary to 22q11.2DS, CHARGE syndrome (coloboma, heart defects, choanal a …
BACKGROUND: Children with complete DiGeorge anomaly (cDGA) have congenital athymia plus a myriad of other challenging clinical condit …
Toxicity evaluation of ConvitVax breast cancer immunotherapy.
Duarte C MA, Carballo O JM, De Gouveia YM, García A, Ruiz D, Gledhill T, González-Marcano E, Convit AF. Duarte C MA, et al. Sci Rep. 2021 Jun 16;11(1):12669. doi: 10.1038/s41598-021-91995-6. Sci Rep. 2021. PMID: 34135375 Free PMC article.
We used standard guidelines for pain, discomfort and distress recognition, continuously evaluated the site of the injection, and completed blood and urine clinical tests. Endpoint necropsy was performed, measuring the weight of organs and processing liver, kidney, thymu …
We used standard guidelines for pain, discomfort and distress recognition, continuously evaluated the site of the injection, and completed b …
Autoimmune disorders of the neuromuscular junction.
Lang B, Vincent A. Lang B, et al. Curr Opin Pharmacol. 2009 Jun;9(3):336-40. doi: 10.1016/j.coph.2009.04.005. Epub 2009 May 8. Curr Opin Pharmacol. 2009. PMID: 19428298 Review.
In myasthenia gravis, the expression of acetylcholine receptors (AChRs) in the thymus is under the control of the autoimmune regulator protein (AIRE), and polymorphisms in the AChR correlate with early onset of disease. In some 'AChR seronegative' patients, thymic abnor …
In myasthenia gravis, the expression of acetylcholine receptors (AChRs) in the thymus is under the control of the autoimmune regulato …
γ-secretase inhibitors and modulators for the treatment of Alzheimer's disease: disappointments and hopes.
Imbimbo BP, Giardina GA. Imbimbo BP, et al. Curr Top Med Chem. 2011;11(12):1555-70. doi: 10.2174/156802611795860942. Curr Top Med Chem. 2011. PMID: 21510832 Review.
Behavioral studies are also scarce with only one study indicating positive cognitive effects of a peptidomimetic compound acutely administered (DAPT). gamma-Secretase inhibitors may cause abnormalities in the gastrointestinal tract, thymus, spleen and skin in experi …
Behavioral studies are also scarce with only one study indicating positive cognitive effects of a peptidomimetic compound acutely administer …
Anesthesia and myasthenia gravis.
Baraka A. Baraka A. Middle East J Anaesthesiol. 1993 Feb;12(1):9-35. Middle East J Anaesthesiol. 1993. PMID: 8316155 Review.
Repetitive nerve stimulation results in a decremental response. The disease is frequently associated with morphological abnormalities of the thymus. In young patients, thymic hyperplasia is common while thymoma is more frequent in elderly patients. ...
Repetitive nerve stimulation results in a decremental response. The disease is frequently associated with morphological abnormalities …
146 results