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Page 1
Effects of growth hormone treatment on thyroid function in pediatric patients with Prader-Willi syndrome.
Oto Y, Murakami N, Matsubara K, Saima S, Ogata H, Ihara H, Nagai T, Matsubara T. Oto Y, et al. Am J Med Genet A. 2020 Apr;182(4):659-663. doi: 10.1002/ajmg.a.61499. Epub 2020 Feb 3. Am J Med Genet A. 2020. PMID: 32011826
In 49 of 51 patients, the TSH response to TRH administration showed a physiologically normal pattern; in two patients (4.0%), the pattern suggested hypothalamic hypothyroidism (delayed and prolonged TSH peak after TRH administration). ...
In 49 of 51 patients, the TSH response to TRH administration showed a physiologically normal pattern; in two patients (4.0%), the pattern su …
Thyroid abnormalities after therapeutic external radiation.
Hancock SL, McDougall IR, Constine LS. Hancock SL, et al. Int J Radiat Oncol Biol Phys. 1995 Mar 30;31(5):1165-70. doi: 10.1016/0360-3016(95)00019-U. Int J Radiat Oncol Biol Phys. 1995. PMID: 7713780 Free article. Review.
Radiation doses to the thyroid that exceed approximately 26 Gy frequently produce hypothyroidism, which may be clinically overt or subclinical, as manifested by increased serum thyrotropin and normal serum-free thyroxine concentrations. Pituitary or hypothalamic hypothy …
Radiation doses to the thyroid that exceed approximately 26 Gy frequently produce hypothyroidism, which may be clinically overt or subclinic …
Dynamic MRI in the congenital agenesis of the neural pituitary stalk syndrome: the role of the vascular pituitary stalk in predicting residual anterior pituitary function.
Maghnie M, Genovese E, Villa A, Spagnolo L, Campan R, Severi F. Maghnie M, et al. Clin Endocrinol (Oxf). 1996 Sep;45(3):281-90. doi: 10.1046/j.1365-2265.1996.00789.x. Clin Endocrinol (Oxf). 1996. PMID: 8949565
In one 10-year-old with IGHD at the time of presentation (6 years) and no pituitary stalk seen after Gd-DTPA, subclinical hypothalamic hypothyroidism and suspected hypogonadotropic hypogonadism were documented. ...
In one 10-year-old with IGHD at the time of presentation (6 years) and no pituitary stalk seen after Gd-DTPA, subclinical hypothalamic …
Thyroid function in severely traumatized patients with or without head injury.
Chioléro RL, Lemarchand-Béraud T, Schutz Y, de Tribolet N, Bayer-Berger M, Freeman J. Chioléro RL, et al. Acta Endocrinol (Copenh). 1988 Jan;117(1):80-6. doi: 10.1530/acta.0.1170080. Acta Endocrinol (Copenh). 1988. PMID: 3132788
These findings show that a typical low T3 and low T4 syndrome is present after severe trauma in patients with multiple injury as well as with head injury. Primary hypothyroidism can be excluded, pituitary or hypothalamic hypothyroidism is likely in these patients... …
These findings show that a typical low T3 and low T4 syndrome is present after severe trauma in patients with multiple injury as well as wit …
Primary idiopathic hypothalamic hypothyroidism. Report of four cases.
Gharib H, Abboud CF. Gharib H, et al. Am J Med. 1987 Jul;83(1):171-4. doi: 10.1016/0002-9343(87)90515-8. Am J Med. 1987. PMID: 3111258
One man and three women with hypothalamic hypothyroidism are described; they had isolated thyrotropin-releasing hormone deficiency, otherwise normal pituitary function, and no identifiable central nervous system anatomic abnormality. ...In two patients, hypothyroidi …
One man and three women with hypothalamic hypothyroidism are described; they had isolated thyrotropin-releasing hormone defici …
Thyroid hemiagenesis and elevated thyrotropin levels in a child with Williams syndrome.
Cammareri V, Vignati G, Nocera G, Beck-Peccoz P, Persani L. Cammareri V, et al. Am J Med Genet. 1999 Aug 27;85(5):491-4. doi: 10.1002/(sici)1096-8628(19990827)85:5<491::aid-ajmg11>3.0.co;2-z. Am J Med Genet. 1999. PMID: 10405448
These abnormalities are similar to those seen in patients with hypothalamic hypothyroidism. Thyroid function is not a recognized manifestation of WS and is not routinely investigated. ...
These abnormalities are similar to those seen in patients with hypothalamic hypothyroidism. Thyroid function is not a recogniz …
Long-term endocrine sequelae after treatment of medulloblastoma: prospective study of growth and thyroid function.
Oberfield SE, Allen JC, Pollack J, New MI, Levine LS. Oberfield SE, et al. J Pediatr. 1986 Feb;108(2):219-23. doi: 10.1016/s0022-3476(86)80986-6. J Pediatr. 1986. PMID: 3944706
Elevated thyroid-stimulating hormone levels were noted in 15 of 22 patients; one patient had hypothalamic hypothyroidism. Thus, the late effects of therapy for medulloblastoma include frequent endocrine morbidity involving hypothalamic-pituitary and thyroid dysfunct …
Elevated thyroid-stimulating hormone levels were noted in 15 of 22 patients; one patient had hypothalamic hypothyroidism. Thus …
Secretion of thyrotropin with reduced concanavalin-A-binding activity in patients with severe nonthyroid illness.
Lee HY, Suhl J, Pekary AE, Hershman JM. Lee HY, et al. J Clin Endocrinol Metab. 1987 Nov;65(5):942-5. doi: 10.1210/jcem-65-5-942. J Clin Endocrinol Metab. 1987. PMID: 3667887
Paradoxically, serum TSH is usually in the normal range. The data suggest a diagnosis of hypothalamic hypothyroidism, in which TSH may have reduced biological activity because TRH, which is necessary for key steps in the glycosylation of TSH, is deficient. ...
Paradoxically, serum TSH is usually in the normal range. The data suggest a diagnosis of hypothalamic hypothyroidism, in which …