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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1953 2
1954 2
1955 4
1956 3
1957 4
1958 3
1959 2
1963 2
1964 11
1965 30
1966 29
1967 50
1968 53
1969 55
1970 69
1971 79
1972 106
1973 88
1974 102
1975 100
1976 78
1977 88
1978 83
1979 84
1980 90
1981 89
1982 88
1983 112
1984 138
1985 121
1986 130
1987 115
1988 112
1989 130
1990 144
1991 100
1992 136
1993 148
1994 143
1995 153
1996 136
1997 154
1998 153
1999 186
2000 185
2001 181
2002 204
2003 223
2004 253
2005 248
2006 273
2007 264
2008 289
2009 316
2010 325
2011 322
2012 332
2013 342
2014 408
2015 388
2016 399
2017 391
2018 417
2019 466
2020 456
2021 476
2022 457
2023 451
2024 175

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11,006 results

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Page 1
Optimal Thyroid Hormone Replacement.
Jonklaas J. Jonklaas J. Endocr Rev. 2022 Mar 9;43(2):366-404. doi: 10.1210/endrev/bnab031. Endocr Rev. 2022. PMID: 34543420 Free PMC article.
Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed. ...This is not supported by the majority of randomized clinical trials, but may be supported by other studies providing lower-quality evidence and by animal studies. ...
Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed. ...This is not supported by the majority of …
Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document.
Jonklaas J, Bianco AC, Cappola AR, Celi FS, Fliers E, Heuer H, McAninch EA, Moeller LC, Nygaard B, Sawka AM, Watt T, Dayan CM. Jonklaas J, et al. Thyroid. 2021 Feb;31(2):156-182. doi: 10.1089/thy.2020.0720. Thyroid. 2021. PMID: 33276704 Free PMC article. Review.
Background: Fourteen clinical trials have not shown a consistent benefit of combination therapy with levothyroxine (LT4) and liothyronine (LT3). ...After review and revision of the material and Summary Statements, there was agreement that there was equipoise for a new c …
Background: Fourteen clinical trials have not shown a consistent benefit of combination therapy with levothyroxine (LT4) and liothyro …
Prevalence of statin intolerance: a meta-analysis.
Bytyçi I, Penson PE, Mikhailidis DP, Wong ND, Hernandez AV, Sahebkar A, Thompson PD, Mazidi M, Rysz J, Pella D, Reiner Ž, Toth PP, Banach M. Bytyçi I, et al. Eur Heart J. 2022 Sep 7;43(34):3213-3223. doi: 10.1093/eurheartj/ehac015. Eur Heart J. 2022. PMID: 35169843 Free PMC article.
The secondary endpoint was to identify possible risk factors for SI. A random-effects model was applied to estimate the overall pooled prevalence. A total of 176 studies [112 randomized controlled trials (RCTs); 64 cohort studies] with 4 143 517 patients were ultima …
The secondary endpoint was to identify possible risk factors for SI. A random-effects model was applied to estimate the overall poole …
Comparative safety of immune checkpoint inhibitors in cancer: systematic review and network meta-analysis.
Xu C, Chen YP, Du XJ, Liu JQ, Huang CL, Chen L, Zhou GQ, Li WF, Mao YP, Hsu C, Liu Q, Lin AH, Tang LL, Sun Y, Ma J. Xu C, et al. BMJ. 2018 Nov 8;363:k4226. doi: 10.1136/bmj.k4226. BMJ. 2018. PMID: 30409774 Free PMC article.
High quality, single arm trials and placebo controlled trials on ICI drugs were selected to establish a validation group. RESULTS: 36 head-to-head phase II and III randomised trials (n=15 370) were included. The general safety of ICI drugs ranked from high to low for all a …
High quality, single arm trials and placebo controlled trials on ICI drugs were selected to establish a validation group. RESULTS: 36 head-t …
Incidence of Endocrine Dysfunction Following the Use of Different Immune Checkpoint Inhibitor Regimens: A Systematic Review and Meta-analysis.
Barroso-Sousa R, Barry WT, Garrido-Castro AC, Hodi FS, Min L, Krop IE, Tolaney SM. Barroso-Sousa R, et al. JAMA Oncol. 2018 Feb 1;4(2):173-182. doi: 10.1001/jamaoncol.2017.3064. JAMA Oncol. 2018. PMID: 28973656 Free PMC article.
Inferences on the incidence of AEs were made using log-odds random effects models. MAIN OUTCOMES AND MEASURES: Incidence of all-grade hypothyroidism, hyperthyroidism, hypophysitis, primary adrenal insufficiency, and insulin-deficient diabetes. RESULTS: Overall, 38 …
Inferences on the incidence of AEs were made using log-odds random effects models. MAIN OUTCOMES AND MEASURES: Incidence of all-grade …
Risk factors for gestational diabetes: An umbrella review of meta-analyses of observational studies.
Giannakou K, Evangelou E, Yiallouros P, Christophi CA, Middleton N, Papatheodorou E, Papatheodorou SI. Giannakou K, et al. PLoS One. 2019 Apr 19;14(4):e0215372. doi: 10.1371/journal.pone.0215372. eCollection 2019. PLoS One. 2019. PMID: 31002708 Free PMC article. Review.
Fifty (82%) associations had nominally statistically significant findings (P<0.05), while only 15 (25%) were significant at P<10-6 under the random-effects model. Only four risk factors presented convincing evidence:, low vs. normal BMI (cohort studies), BMI ~30-35 k …
Fifty (82%) associations had nominally statistically significant findings (P<0.05), while only 15 (25%) were significant at P<10-6 und …
Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial.
Sharma AK, Basu I, Singh S. Sharma AK, et al. J Altern Complement Med. 2018 Mar;24(3):243-248. doi: 10.1089/acm.2017.0183. Epub 2017 Aug 22. J Altern Complement Med. 2018. PMID: 28829155 Clinical Trial.
BACKGROUND: Subclinical hypothyroidism, a thyroid disorder without obvious symptoms of thyroid deficiency, occurs in 3%-8% of the global population. ...Fifty subjects with elevated serum thyroid stimulating hormone (TSH) levels (4.5-10 muIU/L) aged between 18 and 50 were …
BACKGROUND: Subclinical hypothyroidism, a thyroid disorder without obvious symptoms of thyroid deficiency, occurs in 3%-8% of the glo …
Thyroid Status During Pregnancy in Women With Polycystic Ovary Syndrome and the Effect of Metformin.
Trouva A, Alvarsson M, Calissendorff J, Åsvold BO, Vanky E, Hirschberg AL. Trouva A, et al. Front Endocrinol (Lausanne). 2022 Feb 21;13:772801. doi: 10.3389/fendo.2022.772801. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35265033 Free PMC article. Clinical Trial.
OBJECTIVE: Polycystic ovary syndrome (PCOS) and hypothyroidism are related conditions, and both are associated with adverse pregnancy outcomes. ...A smaller decrease in fT4 correlated to less weight gain and tended to be associated with a lower risk of gestational diabetes …
OBJECTIVE: Polycystic ovary syndrome (PCOS) and hypothyroidism are related conditions, and both are associated with adverse pregnancy …
11,006 results
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