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Treatment of hereditary hypotrichosis simplex of the scalp with topical gentamicin.
Peled A, Samuelov L, Sarig O, Bochner R, Malki L, Pavlovsky M, Pichinuk E, Weil M, Sprecher E. Peled A, et al. Br J Dermatol. 2020 Jul;183(1):114-120. doi: 10.1111/bjd.18718. Epub 2019 Dec 26. Br J Dermatol. 2020. PMID: 31746457 Clinical Trial.
BACKGROUND: Hypotrichosis simplex of the scalp (HSS) is characterized by progressive loss of scalp hair that results in almost complete baldness at a young age. ...What's already known about this topic? Hypotrichosis simplex of …
BACKGROUND: Hypotrichosis simplex of the scalp (HSS) is characterized by progressive loss of scalp hair t …
A gene for hypotrichosis simplex of the scalp maps to chromosome 6p21.3.
Betz RC, Lee YA, Bygum A, Brandrup F, Bernal AI, Toribio J, Alvarez JI, Kukuk GM, Ibsen HH, Rasmussen HB, Wienker TF, Reis A, Propping P, Kruse R, Cichon S, Nöthen MM. Betz RC, et al. Am J Hum Genet. 2000 Jun;66(6):1979-83. doi: 10.1086/302934. Epub 2000 May 2. Am J Hum Genet. 2000. PMID: 10793007 Free PMC article.
Hypotrichosis simplex of the scalp (HSS) is an autosomal dominant form of isolated alopecia causing almost complete loss of scalp hair, with onset in childhood. After exclusion of candidate regions previously associated with hair-loss disorders, …
Hypotrichosis simplex of the scalp (HSS) is an autosomal dominant form of isolated alopecia causing almos …
A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin.
Caubet C, Bousset L, Clemmensen O, Sourigues Y, Bygum A, Chavanas S, Coudane F, Hsu CY, Betz RC, Melki R, Simon M, Serre G. Caubet C, et al. FASEB J. 2010 Sep;24(9):3416-26. doi: 10.1096/fj.10-155622. Epub 2010 May 6. FASEB J. 2010. PMID: 20448140
Heterozygous nonsense mutations in the CDSN gene encoding corneodesmosin (CDSN), an adhesive protein expressed in cornified epithelia and hair follicles, cause hypotrichosis simplex of the scalp (HSS), a nonsyndromic form of alopecia. ...We show …
Heterozygous nonsense mutations in the CDSN gene encoding corneodesmosin (CDSN), an adhesive protein expressed in cornified epithelia and ha …