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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1978 1
1981 2
1991 2
1994 2
1997 1
1998 1
1999 2
2000 3
2002 1
2003 2
2004 2
2005 2
2006 3
2007 3
2008 4
2009 6
2010 2
2011 6
2012 5
2013 7
2014 5
2015 7
2016 4
2017 10
2018 10
2019 5
2020 13
2021 15
2022 16
2023 15
2024 9

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139 results

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Page 1
A new method for measuring daytime sleepiness: the Epworth sleepiness scale.
Johns MW. Johns MW. Sleep. 1991 Dec;14(6):540-5. doi: 10.1093/sleep/14.6.540. Sleep. 1991. PMID: 1798888
They rated the chances that they would doze off or fall asleep when in eight different situations commonly encountered in daily life. Total ESS scores significantly distinguished normal subjects from patients in various diagnostic groups including obstructive sleep apnea s …
They rated the chances that they would doze off or fall asleep when in eight different situations commonly encountered in daily life. Total …
The immunopathogenesis of narcolepsy type 1.
Liblau RS, Latorre D, Kornum BR, Dauvilliers Y, Mignot EJ. Liblau RS, et al. Nat Rev Immunol. 2024 Jan;24(1):33-48. doi: 10.1038/s41577-023-00902-9. Epub 2023 Jul 3. Nat Rev Immunol. 2024. PMID: 37400646 Review.
An immune-mediated pathology for NT1 has long been suspected given its exceptionally tight association with the MHC class II allele HLA-DQB1*06:02, as well as recent genetic evidence showing associations with polymorphisms of T cell receptor genes and other immune-relevant loci a …
An immune-mediated pathology for NT1 has long been suspected given its exceptionally tight association with the MHC class II allele HLA-DQB1 …
Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.
Maski K, Trotti LM, Kotagal S, Robert Auger R, Swick TJ, Rowley JA, Hashmi SD, Watson NF. Maski K, et al. J Clin Sleep Med. 2021 Sep 1;17(9):1895-1945. doi: 10.5664/jcsm.9326. J Clin Sleep Med. 2021. PMID: 34743790 Free PMC article.
METHODS: The American Academy of Sleep Medicine commissioned a task force of experts in sleep medicine to perform a systematic review. Randomized controlled trials and observational studies addressing pharmacological and nonpharmacological interventions for central disorde …
METHODS: The American Academy of Sleep Medicine commissioned a task force of experts in sleep medicine to perform a systematic review. Rando …
Safety and efficacy of pitolisant in children aged 6 years or older with narcolepsy with or without cataplexy: a double-blind, randomised, placebo-controlled trial.
Dauvilliers Y, Lecendreux M, Lammers GJ, Franco P, Poluektov M, Caussé C, Lecomte I, Lecomte JM, Lehert P, Schwartz JC, Plazzi G. Dauvilliers Y, et al. Lancet Neurol. 2023 Apr;22(4):303-311. doi: 10.1016/S1474-4422(23)00036-4. Lancet Neurol. 2023. PMID: 36931805 Clinical Trial.
Participants were required to have a Pediatric Daytime Sleepiness Scale score of 15 or greater and to have not received psychostimulants for at least 14 days before enrolment; participants who needed anticataplectics (including sodium oxybate) were required to have been on …
Participants were required to have a Pediatric Daytime Sleepiness Scale score of 15 or greater and to have not received psychostimula …
Update on treatment for idiopathic hypersomnia.
Evangelista E, Lopez R, Dauvilliers Y. Evangelista E, et al. Expert Opin Investig Drugs. 2018 Feb;27(2):187-192. doi: 10.1080/13543784.2018.1417385. Epub 2018 Jan 3. Expert Opin Investig Drugs. 2018. PMID: 29250981 Review.
Idiopathic hypersomnia (IH) is a poorly characterized orphan central disorder of hypersomnolence responsible for excessive daytime sleepiness (EDS), prolonged nighttime sleep and sleep inertia that often require long-term symptomatic stimulant medication. ...Areas c
Idiopathic hypersomnia (IH) is a poorly characterized orphan central disorder of hypersomnolence responsible for excessive day
Excessive daytime sleepiness: an emerging marker of cardiovascular risk.
Bock J, Covassin N, Somers V. Bock J, et al. Heart. 2022 Oct 28;108(22):1761-1766. doi: 10.1136/heartjnl-2021-319596. Heart. 2022. PMID: 35102000 Free PMC article. Review.
The purpose of this review is twofold: first, to highlight evidence that EDS increases cardiovascular risk in the presence of sleep disorders such as obstructive sleep apnoea, narcolepsy and idiopathic hypersomnia and second, to propose the notion that EDS may also …
The purpose of this review is twofold: first, to highlight evidence that EDS increases cardiovascular risk in the presence of sleep disorder …
Frequency and severity of autonomic symptoms in idiopathic hypersomnia.
Miglis MG, Schneider L, Kim P, Cheung J, Trotti LM. Miglis MG, et al. J Clin Sleep Med. 2020 May 15;16(5):749-756. doi: 10.5664/jcsm.8344. Epub 2020 Feb 10. J Clin Sleep Med. 2020. PMID: 32039754 Free PMC article.
METHODS: One hundred thirty-eight patients with idiopathic hypersomnia and 81 age- and sex-matched controls were recruited through the website of the Hypersomnia Foundation, a US-based patient advocacy group. Twenty-four patients with confirmed idiopathic
METHODS: One hundred thirty-eight patients with idiopathic hypersomnia and 81 age- and sex-matched controls were recruited thr …
Measurement of symptoms in idiopathic hypersomnia: The Idiopathic Hypersomnia Severity Scale.
Dauvilliers Y, Evangelista E, Barateau L, Lopez R, Chenini S, Delbos C, Beziat S, Jaussent I. Dauvilliers Y, et al. Neurology. 2019 Apr 9;92(15):e1754-e1762. doi: 10.1212/WNL.0000000000007264. Epub 2019 Mar 13. Neurology. 2019. PMID: 30867266
OBJECTIVE: To validate the Idiopathic Hypersomnia Severity Scale (IIHSS), a self-report measure of hypersomnolence symptoms, consequences, and responsiveness to treatment. ...Among the 210 participants who fully completed the IHSS, there were 57 untreated and 43 tre …
OBJECTIVE: To validate the Idiopathic Hypersomnia Severity Scale (IIHSS), a self-report measure of hypersomnolence symptoms, c …
Idiopathic Hypersomnia Severity Scale to better quantify symptoms severity and their consequences in idiopathic hypersomnia.
Rassu AL, Evangelista E, Barateau L, Chenini S, Lopez R, Jaussent I, Dauvilliers Y. Rassu AL, et al. J Clin Sleep Med. 2022 Feb 1;18(2):617-629. doi: 10.5664/jcsm.9682. J Clin Sleep Med. 2022. PMID: 34596041 Free PMC article.
STUDY OBJECTIVES: To assess the responsiveness of the Idiopathic Hypersomnia Severity Scale (IHSS) to medications and estimate the minimum clinically important difference, to report clinically relevant score ranges, and to confirm its psychometric properties …
STUDY OBJECTIVES: To assess the responsiveness of the Idiopathic Hypersomnia Severity Scale (IHSS) to medications and estimate …
Safety and pharmacodynamics of a single infusion of danavorexton in adults with idiopathic hypersomnia.
Mignot E, Bogan RK, Emsellem H, Foldvary-Schaefer N, Naylor M, Neuwirth R, Faessel H, Swick T, Olsson T. Mignot E, et al. Sleep. 2023 Sep 8;46(9):zsad049. doi: 10.1093/sleep/zsad049. Sleep. 2023. PMID: 36883238 Free PMC article. Clinical Trial.
STUDY OBJECTIVES: Idiopathic hypersomnia (IH) is a chronic disorder characterized by excessive daytime sleepiness unexplained by another disorder or drug/medication use. ...There were no deaths or TEAEs leading to discontinuation. Improvements in MWT, KSS, and PVT …
STUDY OBJECTIVES: Idiopathic hypersomnia (IH) is a chronic disorder characterized by excessive daytime sleepiness unexplained …
139 results