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IgG4 as a Biomarker in Graves' Orbitopathy.
Olejarz M, Szczepanek-Parulska E, Dadej D, Sawicka-Gutaj N, Domin R, Ruchała M. Olejarz M, et al. Mediators Inflamm. 2021 Jun 10;2021:5590471. doi: 10.1155/2021/5590471. eCollection 2021. Mediators Inflamm. 2021. PMID: 34220335 Free PMC article. Review.
Typical signs of GO accompanied by increased concentration of IgG4 include younger age at diagnosis, and more severe course of the disease with a higher Clinical Activity Score (CAS).. ...
Typical signs of GO accompanied by increased concentration of IgG4 include younger age at diagnosis, and more severe course of the di …
Heritability analysis of IgG4 antibodies in autoimmune thyroid disease.
Outschoorn IM, Talor MV, Burek CL, Hoffman WH, Rose NR. Outschoorn IM, et al. Autoimmunity. 2014 Aug;47(5):320-6. doi: 10.3109/08916934.2014.897331. Epub 2014 Mar 13. Autoimmunity. 2014. PMID: 24624991
Since high and low IgG4 levels give different heritability plots, these findings may represent a more severe fibrotic form of thyroiditis with a distinct genetic background. Hence a simple predictive approach is offered by this screening tool for the disease in patients an …
Since high and low IgG4 levels give different heritability plots, these findings may represent a more severe fibrotic form of thyroiditis wi …