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131 results

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Quoted phrase not found in phrase index: "Immunodeficiency 65, susceptibility to viral infections"
Page 1
Novel genes and sex differences in COVID-19 severity.
Cruz R, Diz-de Almeida S, López de Heredia M, Quintela I, Ceballos FC, Pita G, Lorenzo-Salazar JM, González-Montelongo R, Gago-Domínguez M, Sevilla Porras M, Tenorio Castaño JA, Nevado J, Aguado JM, Aguilar C, Aguilera-Albesa S, Almadana V, Almoguera B, Alvarez N, Andreu-Bernabeu Á, Arana-Arri E, Arango C, Arranz MJ, Artiga MJ, Baptista-Rosas RC, Barreda-Sánchez M, Belhassen-Garcia M, Bezerra JF, Bezerra MAC, Boix-Palop L, Brion M, Brugada R, Bustos M, Calderón EJ, Carbonell C, Castano L, Castelao JE, Conde-Vicente R, Cordero-Lorenzana ML, Cortes-Sanchez JL, Corton M, Darnaude MT, De Martino-Rodríguez A, Del Campo-Pérez V, Diaz de Bustamante A, Domínguez-Garrido E, Luchessi AD, Eiros R, Estigarribia Sanabria GM, Carmen Fariñas M, Fernández-Robelo U, Fernández-Rodríguez A, Fernández-Villa T, Gil-Fournier B, Gómez-Arrue J, González Álvarez B, Gonzalez Bernaldo de Quirós F, González-Peñas J, Gutiérrez-Bautista JF, Herrero MJ, Herrero-Gonzalez A, Jimenez-Sousa MA, Lattig MC, Liger Borja A, Lopez-Rodriguez R, Mancebo E, Martín-López C, Martín V, Martinez-Nieto O, Martinez-Lopez I, Martinez-Resendez MF, Martinez-Perez A, Mazzeu JF, Merayo Macías E, Minguez P, Moreno Cuerda V, Silbiger V… See abstract for full author list ➔ Cruz R, et al. Hum Mol Genet. 2022 Nov 10;31(22):3789-3806. doi: 10.1093/hmg/ddac132. Hum Mol Genet. 2022. PMID: 35708486 Free PMC article.
Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE consortium). ...Six of the COVID-19 HGI discovered …
Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an e …
Tuberculosis in Poland in 2020.
Korzeniewska-Koseła M, Wesołowski S. Korzeniewska-Koseła M, et al. Przegl Epidemiol. 2022;76(4):528-546. doi: 10.32394/pe.76.48. Przegl Epidemiol. 2022. PMID: 37017237
MATERIAL AND METHODS: Analysis of case-based data on TB patients from National TB Register, data on anti-TB drug susceptibility in cases notified in 2020, data from Statistics Poland on deaths from tuberculosis in 2019, data from National Institute of Public Health NIH - N …
MATERIAL AND METHODS: Analysis of case-based data on TB patients from National TB Register, data on anti-TB drug susceptibility in ca …
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.
Matuozzo D, Talouarn E, Marchal A, Zhang P, Manry J, Seeleuthner Y, Zhang Y, Bolze A, Chaldebas M, Milisavljevic B, Gervais A, Bastard P, Asano T, Bizien L, Barzaghi F, Abolhassani H, Abou Tayoun A, Aiuti A, Alavi Darazam I, Allende LM, Alonso-Arias R, Arias AA, Aytekin G, Bergman P, Bondesan S, Bryceson YT, Bustos IG, Cabrera-Marante O, Carcel S, Carrera P, Casari G, Chaïbi K, Colobran R, Condino-Neto A, Covill LE, Delmonte OM, El Zein L, Flores C, Gregersen PK, Gut M, Haerynck F, Halwani R, Hancerli S, Hammarström L, Hatipoğlu N, Karbuz A, Keles S, Kyheng C, Leon-Lopez R, Franco JL, Mansouri D, Martinez-Picado J, Metin Akcan O, Migeotte I, Morange PE, Morelle G, Martin-Nalda A, Novelli G, Novelli A, Ozcelik T, Palabiyik F, Pan-Hammarström Q, de Diego RP, Planas-Serra L, Pleguezuelo DE, Prando C, Pujol A, Reyes LF, Rivière JG, Rodriguez-Gallego C, Rojas J, Rovere-Querini P, Schlüter A, Shahrooei M, Sobh A, Soler-Palacin P, Tandjaoui-Lambiotte Y, Tipu I, Tresoldi C, Troya J, van de Beek D, Zatz M, Zawadzki P, Al-Muhsen SZ, Alosaimi MF, Alsohime FM, Baris-Feldman H, Butte MJ, Constantinescu SN, Cooper MA, Dalgard CL, Fellay J, Heath JR, Lau YL, Lifton RP, Maniatis T, Mogensen TH, v… See abstract for full author list ➔ Matuozzo D, et al. Genome Med. 2023 Apr 5;15(1):22. doi: 10.1186/s13073-023-01173-8. Genome Med. 2023. PMID: 37020259 Free PMC article.
Under a recessive model, the most significant gene with at-risk variants was TLR7, with an OR of 27.68 (95%CI 1.5-528.7, P = 1.1 10(-4)) for biochemically loss-of-function (bLOF) variants. We replicated the enrichment in rare predicted LOF (pLOF) variants at 13 influenza …
Under a recessive model, the most significant gene with at-risk variants was TLR7, with an OR of 27.68 (95%CI 1.5-528.7, P = 1.1 10(-4)) for …
Clinical and Microbiological Features of Salmonella Meningitis in a South African Population, 2003-2013.
Keddy KH, Sooka A, Musekiwa A, Smith AM, Ismail H, Tau NP, Crowther-Gibson P, Angulo FJ, Klugman KP; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA). Keddy KH, et al. Clin Infect Dis. 2015 Nov 1;61 Suppl 4(Suppl 4):S272-82. doi: 10.1093/cid/civ685. Clin Infect Dis. 2015. PMID: 26449942 Free PMC article. Review.
BACKGROUND: The clinical and microbiological characteristics of nontyphoidal Salmonella (NTS) meningitis in South Africa, where human immunodeficiency virus (HIV) prevalence is high (approximately 15% in persons 15 years of age), were reviewed. ...CONCLUSIONS: NTS m …
BACKGROUND: The clinical and microbiological characteristics of nontyphoidal Salmonella (NTS) meningitis in South Africa, where human imm …
Drug resistance in children and adolescents with HIV in Panama.
Ventosa-Cubillo J, Pinzón R, González-Alba JM, Estripeaut D, Navarro ML, Holguín Á. Ventosa-Cubillo J, et al. J Antimicrob Chemother. 2023 Feb 1;78(2):423-435. doi: 10.1093/jac/dkac407. J Antimicrob Chemother. 2023. PMID: 36454248 Free PMC article.
METHODS: During 2018-19, plasma was collected from 76 HIV-infected children/adolescents (5 ART-naive, 71 treated) in Panama for HIV-1 DRM pol analysis, predicted antiretroviral (ARV) susceptibility by Stanford, and HIV-1 variant phylogenetic characterization. ...Seq …
METHODS: During 2018-19, plasma was collected from 76 HIV-infected children/adolescents (5 ART-naive, 71 treated) in Panama for HIV-1 DRM po …
HIV vaccine acceptability: a systematic review and meta-analysis.
Newman PA, Logie C. Newman PA, et al. AIDS. 2010 Jul 17;24(11):1749-56. doi: 10.1097/qad.0b013e32833adbe8. AIDS. 2010. PMID: 20597165 Review.
We conducted meta-analysis on studies reporting correlates or predictors of HIV vaccine acceptability. RESULTS: Twenty studies (n=7576) reported HIV vaccine acceptability ranging from 37.2 to 94.0 on a 100-point scale; weighted mean acceptability =65.6 (SD=21.1). .. …
We conducted meta-analysis on studies reporting correlates or predictors of HIV vaccine acceptability. RESULTS: Twenty studies (n=757 …
Multidrug-resistant tuberculosis in Imo State, Southeast, Nigeria.
E Ahiarakwem II, Ekejindu IM, Akujobi CN, Aghanya IN. E Ahiarakwem II, et al. Niger J Clin Pract. 2020 Aug;23(8):1172-1177. doi: 10.4103/njcp.njcp_192_19. Niger J Clin Pract. 2020. PMID: 32788498
The isolates were then confirmed as Mycobacterium tuberculosis using SD Bioline Rapid Diagnostic Tests before being subjected to drug susceptibility testing to first-line anti-TB drugs. MDR-TB was determined by isolates being resistant to both isoniazid and rifampicin. HIV …
The isolates were then confirmed as Mycobacterium tuberculosis using SD Bioline Rapid Diagnostic Tests before being subjected to drug sus …
Microbiological and clinical characteristics of Streptococcus pneumoniae serotype 3 infection and risk factors for severe outcome: A multicenter observational study.
Aydin MA, Janapatla RP, Chen CL, Li HC, Su LH, Chiu CH. Aydin MA, et al. J Microbiol Immunol Infect. 2023 Jun;56(3):598-604. doi: 10.1016/j.jmii.2023.01.013. Epub 2023 Feb 2. J Microbiol Immunol Infect. 2023. PMID: 36774315 Free article.
RESULTS: A total of 146 isolates were collected, including 12 isolates regarded as colonizers. Among 134 infected cases, 54 (40.3%) were aged 65 and older. Mortality was significantly associated with diabetes mellitus, immunosuppression, immunodeficiency, high-risk …
RESULTS: A total of 146 isolates were collected, including 12 isolates regarded as colonizers. Among 134 infected cases, 54 (40.3%) were age …
The role of a functional variant of TYK2 in vasculitides and infections.
Ortiz-Fernández L, López-Mejias R, Carmona FD, Castaño-Nuñez AL, Lyons PA, Caruz A, Gónzalez-Escribano MF, Smith KGC, González-Gay MA, Martin J; Spanish GCA Study Group, IgAV Study Group, AAV Study Group and HIV Study Group. Ortiz-Fernández L, et al. Clin Exp Rheumatol. 2020 Sep-Oct;38(5):949-955. Epub 2020 Mar 10. Clin Exp Rheumatol. 2020. PMID: 32167874 Free article.
A functional variant of this gene has been identified to play a protective role in multiple autoimmune diseases. The goal of this study was to evaluate the involvement of this variant of TYK2 in vasculitides [giant cell arteritis (GCA), ANCA-associated vasculitis (AAV) and …
A functional variant of this gene has been identified to play a protective role in multiple autoimmune diseases. The goal of this stu …
Rifampicin-Monoresistant Tuberculosis Is Not the Same as Multidrug-Resistant Tuberculosis: a Descriptive Study from Khayelitsha, South Africa.
Salaam-Dreyer Z, Streicher EM, Sirgel FA, Menardo F, Borrell S, Reinhard M, Doetsch A, Cudahy PGT, Mohr-Holland E, Daniels J, Dippenaar A, Nicol MP, Gagneux S, Warren RM, Cox H. Salaam-Dreyer Z, et al. Antimicrob Agents Chemother. 2021 Oct 18;65(11):e0036421. doi: 10.1128/AAC.00364-21. Epub 2021 Aug 30. Antimicrob Agents Chemother. 2021. PMID: 34460307 Free PMC article.
Rifampin monoresistance (RMR; rifampin resistance and isoniazid susceptibility) accounts for 38% of all rifampin-resistant tuberculosis (RR-TB) in South Africa and is increasing. ...Among 10 isolates with an rpoB L430P mutation, 7 were phenotypically susceptible usi …
Rifampin monoresistance (RMR; rifampin resistance and isoniazid susceptibility) accounts for 38% of all rifampin-resistant tuberculos …
131 results