Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1975 1
1978 3
1980 1
1982 1
1986 1
1989 1
1990 2
1991 2
1993 2
1994 2
1996 4
1998 1
2000 2
2001 1
2003 1
2005 2
2006 1
2008 1
2009 2
2010 3
2011 1
2014 1
2015 1
2016 1
2017 3
2018 3
2019 2
2020 4
2021 3
2022 3
2023 4
2024 3

Text availability

Article attribute

Article type

Publication date

Search Results

54 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "In Utero Drug Withdrawal"
Page 1
Neonatal Abstinence Syndrome: Advances in Diagnosis and Treatment.
Wachman EM, Schiff DM, Silverstein M. Wachman EM, et al. JAMA. 2018 Apr 3;319(13):1362-1374. doi: 10.1001/jama.2018.2640. JAMA. 2018. PMID: 29614184 Review.
IMPORTANCE: Neonatal abstinence syndrome, which occurs as a result of in utero opioid exposure, affects between 6.0 and 20 newborns per 1000 live US births. ...Thirteen studies were identified that evaluated established or novel neonatal abstinence syndrome assessment meth …
IMPORTANCE: Neonatal abstinence syndrome, which occurs as a result of in utero opioid exposure, affects between 6.0 and 20 newborns p …
Duration and Timing of In Utero Opioid Exposure and Incidence of Neonatal Withdrawal Syndrome.
Wang Y, Berger L, Durrance C, Kirby RS, Kuo D, Pac J, Ehrenthal DB. Wang Y, et al. Obstet Gynecol. 2023 Sep 1;142(3):603-611. doi: 10.1097/AOG.0000000000005289. Obstet Gynecol. 2023. PMID: 37548391
OBJECTIVE: To evaluate the association between prenatal prescription opioid analgesic exposure (duration, timing) and neonatal opioid withdrawal syndrome (NOWS). METHODS: We conducted a retrospective cohort study of Wisconsin Medicaid-covered singleton live births from 201 …
OBJECTIVE: To evaluate the association between prenatal prescription opioid analgesic exposure (duration, timing) and neonatal opioid wit …
Opioid Treatment for Neonatal Opioid Withdrawal Syndrome: Current Challenges and Future Approaches.
McPhail BT, Emoto C, Butler D, Fukuda T, Akinbi H, Vinks AA. McPhail BT, et al. J Clin Pharmacol. 2021 Jul;61(7):857-870. doi: 10.1002/jcph.1811. Epub 2021 Feb 1. J Clin Pharmacol. 2021. PMID: 33382111 Review.
Chronic intrauterine exposure to psychoactive drugs often results in neonatal opioid withdrawal syndrome (NOWS). When nonpharmacologic measures are insufficient in controlling NOWS, morphine, methadone, and buprenorphine are first-line medications commonly used to treat in …
Chronic intrauterine exposure to psychoactive drugs often results in neonatal opioid withdrawal syndrome (NOWS). When nonpharmacologi …
Short- and long-term complications of in utero exposure to lamotrigine.
Cohen-Israel M, Berger I, Martonovich EY, Klinger G, Stahl B, Linder N. Cohen-Israel M, et al. Br J Clin Pharmacol. 2018 Jan;84(1):189-194. doi: 10.1111/bcp.13437. Epub 2017 Oct 22. Br J Clin Pharmacol. 2018. PMID: 29044597 Free PMC article.
RESULTS: No major malformations were found in the newborns. None of the newborns had significant withdrawal symptoms by Finnegan score. The children were followed-up to the age of 12 years (56.6% were 6-12 years at the time of evaluation). ...
RESULTS: No major malformations were found in the newborns. None of the newborns had significant withdrawal symptoms by Finnegan scor …
A review of pregnancy-induced changes in opioid pharmacokinetics, placental transfer, and fetal exposure: Towards fetomaternal physiologically-based pharmacokinetic modeling to improve the treatment of neonatal opioid withdrawal syndrome.
van Hoogdalem MW, Wexelblatt SL, Akinbi HT, Vinks AA, Mizuno T. van Hoogdalem MW, et al. Pharmacol Ther. 2022 Jun;234:108045. doi: 10.1016/j.pharmthera.2021.108045. Epub 2021 Nov 20. Pharmacol Ther. 2022. PMID: 34813863 Review.
PBPK models can accommodate pregnancy-induced physiological and metabolic changes, thereby providing mechanistic insights into maternal drug disposition and fetal exposure. Fueled by the soaring opioid epidemic in the United States, opioid use during pregnancy continues to …
PBPK models can accommodate pregnancy-induced physiological and metabolic changes, thereby providing mechanistic insights into maternal d …
Is Maternal Methadone Dose Associated with the Severity of Neonatal Abstinence Syndrome?
Smith J, Lafferty M, Boelig RC, Carola D, Adeniyi-Jones S, Kraft WK, Greenspan JS, Aghai ZH. Smith J, et al. Am J Perinatol. 2022 Jul;39(10):1138-1144. doi: 10.1055/s-0040-1721693. Epub 2020 Dec 15. Am J Perinatol. 2022. PMID: 33321531
STUDY DESIGN: This is a retrospective analysis of 574 infants 35 weeks' gestation exposed to methadone in utero, born between August 2006 and May 2018, and who required pharmacological therapy for NAS. ...Methadone maintenance therapy is used during pregnancy to control ma …
STUDY DESIGN: This is a retrospective analysis of 574 infants 35 weeks' gestation exposed to methadone in utero, born between August …
Placental DNA methylation profiles in opioid-exposed pregnancies and associations with the neonatal opioid withdrawal syndrome.
Radhakrishna U, Vishweswaraiah S, Uppala LV, Szymanska M, Macknis J, Kumar S, Saleem-Rasheed F, Aydas B, Forray A, Muvvala SB, Mishra NK, Guda C, Carey DJ, Metpally RP, Crist RC, Berrettini WH, Bahado-Singh RO. Radhakrishna U, et al. Genomics. 2021 May;113(3):1127-1135. doi: 10.1016/j.ygeno.2021.03.006. Epub 2021 Mar 9. Genomics. 2021. PMID: 33711455 Free article.
Opioid abuse during pregnancy can result in Neonatal Opioid Withdrawal Syndrome (NOWS). We investigated genome-wide methylation analyses of 96 placental tissue samples, including 32 prenatally opioid-exposed infants with NOWS who needed therapy (+Opioids/+NOWS), 32 prenata …
Opioid abuse during pregnancy can result in Neonatal Opioid Withdrawal Syndrome (NOWS). We investigated genome-wide methylation analy …
Transplacental methadone exposure and risk of Neonatal Opioid Withdrawal Syndrome.
Bhatt-Mehta V, Jing X, Wang X, Zhu HJ. Bhatt-Mehta V, et al. Pharmacotherapy. 2024 Jan;44(1):22-27. doi: 10.1002/phar.2863. Epub 2023 Aug 23. Pharmacotherapy. 2024. PMID: 37574548
STUDY OBJECTIVE: Neonatal opioid withdrawal syndrome (NOWS) is a condition that often occurs in neonates born to mothers who received methadone treatment for opioid use disorder during pregnancy. ...CONCLUSIONS: The results suggest that methadone permeability across the bl …
STUDY OBJECTIVE: Neonatal opioid withdrawal syndrome (NOWS) is a condition that often occurs in neonates born to mothers who received …
Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome.
Koch S, Jäger-Roman E, Lösche G, Nau H, Rating D, Helge H. Koch S, et al. Acta Paediatr. 1996 Jun;85(6):739-46. doi: 10.1111/j.1651-2227.1996.tb14137.x. Acta Paediatr. 1996. PMID: 8816215 Clinical Trial.
They may also cause pharmacological side effects in the newborn, i.e. sedation and or withdrawal symptoms. We examined the relationship between the maternal antiepileptic therapy, neonatal behaviour and later neurological functions in infancy. The study comprised 40 childr …
They may also cause pharmacological side effects in the newborn, i.e. sedation and or withdrawal symptoms. We examined the relationsh …
Trends in Neonatal Opioid Withdrawal Syndrome and Opioid Exposure Diagnoses Among Infants With Private Health Insurance, 2016-2021: Introduction of the P04.14 ICD-10-CM Code.
Campbell AG, Zhang P, Rosenman MB, Scott E, Wiehe SE. Campbell AG, et al. Public Health Rep. 2024 Jan-Feb;139(1):88-93. doi: 10.1177/00333549231162375. Epub 2023 Apr 29. Public Health Rep. 2024. PMID: 37119181
OBJECTIVE: The opioid epidemic has led to a surge in diagnoses of neonatal opioid withdrawal syndrome (NOWS). Many states track the incidence of NOWS by using the P96.1 International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code for "ne …
OBJECTIVE: The opioid epidemic has led to a surge in diagnoses of neonatal opioid withdrawal syndrome (NOWS). Many states track the i …
54 results