Genetic loci on chromosome 5 are associated with circulating levels of interleukin-5 and eosinophil count in a European population with high risk for cardiovascular disease.
McLeod O, Silveira A, Valdes-Marquez E, Björkbacka H, Almgren P, Gertow K, Gådin JR, Bäcklund A, Sennblad B, Baldassarre D, Veglia F, Humphries SE, Tremoli E, de Faire U, Nilsson J, Melander O, Hopewell JC, Clarke R, Björck HM, Hamsten A, Öhrvik J, Strawbridge RJ; IMPROVE Study Group.
McLeod O, et al.
Cytokine. 2016 May;81:1-9. doi: 10.1016/j.cyto.2016.01.007. Epub 2016 Jan 25.
Cytokine. 2016.
PMID: 26821299
Free PMC article.
Genetic variants in the IL5 locus have been associated with increased risk of CAD and ischemic stroke. In this study we aimed to identify genetic variants associated with IL-5 concentrations and apply a Mendelian randomisation approach to assess IL-5 levels for caus …
Genetic variants in the IL5 locus have been associated with increased risk of CAD and ischemic stroke. In this study we aimed to iden …