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Quoted phrase not found in phrase index: "Increased urinary 11-deoxycorticosterone level"
Page 1
Antihypertensive potential of selected pyrimidine derivatives: Explanation of underlying mechanistic pathways.
Irshad N, Khan AU, Alamgeer, Khan SU, Iqbal MS. Irshad N, et al. Biomed Pharmacother. 2021 Jul;139:111567. doi: 10.1016/j.biopha.2021.111567. Epub 2021 Apr 10. Biomed Pharmacother. 2021. PMID: 33848773 Free article.
In the aorta and heart tissues, the test compounds enhanced glutathione-s-transferase, reduced glutathione and catalase levels, improved cellular architecture, and decreased lipid peroxidation and expression of inflammatory markers: cyclooxygenase 2, tumor necrosis factor …
In the aorta and heart tissues, the test compounds enhanced glutathione-s-transferase, reduced glutathione and catalase levels, impro …
Male pseudohermaphroditism due to 17 alpha-hydroxylase deficiency.
New MI. New MI. J Clin Invest. 1970 Oct;49(10):1930-41. doi: 10.1172/JCI106412. J Clin Invest. 1970. PMID: 5456802 Free PMC article.
Diagnosis was based on extensive studies of steroid metabolism including the following: low urinary excretion of 17-ketosteroids and 17-hydroxycorticoids which did not increase after ACTH; no response of very low plasma testosterone and dehydroepiandrosterone to adr …
Diagnosis was based on extensive studies of steroid metabolism including the following: low urinary excretion of 17-ketosteroids and …
Intermedin ameliorates vascular and renal injury by inhibition of oxidative stress.
Hagiwara M, Bledsoe G, Yang ZR, Smith RS Jr, Chao L, Chao J. Hagiwara M, et al. Am J Physiol Renal Physiol. 2008 Dec;295(6):F1735-43. doi: 10.1152/ajprenal.90427.2008. Epub 2008 Oct 1. Am J Physiol Renal Physiol. 2008. PMID: 18829738 Free PMC article.
Expression of human IMD was detected in the rat kidney via immunohistochemistry. IMD administration significantly lowered blood pressure, increased urine volume, and restored creatinine clearance. IMD also dramatically decreased superoxide formation and media thickness in …
Expression of human IMD was detected in the rat kidney via immunohistochemistry. IMD administration significantly lowered blood pressure, …
Role of atrial natriuretic peptide in mineralocorticoid escape phenomenon in patients with primary aldosteronism.
Nakamura T, Ichikawa S, Sakamaki T, Sato K, Kogure M, Tajima Y, Kato T, Murata K. Nakamura T, et al. Proc Soc Exp Biol Med. 1987 Sep;185(4):448-54. doi: 10.3181/00379727-185-42568. Proc Soc Exp Biol Med. 1987. PMID: 2956609
Plasma ANP levels increased significantly (P less than 0.05) from 26 +/- 4 pg/ml during the control period to 195 +/- 47 pg/ml on the 13th day after stopping spironolactone. The data of the urinary sodium excretion showed the escape from sodium-retaining effe …
Plasma ANP levels increased significantly (P less than 0.05) from 26 +/- 4 pg/ml during the control period to 195 +/- 47 pg/ml …
Dietary supplementation of Huangshan Maofeng green tea preventing hypertension of older C57BL/6 mice induced by desoxycorticosterone acetate and salt.
Liu Z, Xiao M, Du Z, Li M, Guo H, Yao M, Wan X, Xie Z. Liu Z, et al. J Nutr Biochem. 2021 Feb;88:108530. doi: 10.1016/j.jnutbio.2020.108530. Epub 2020 Oct 17. J Nutr Biochem. 2021. PMID: 33080347 Free article.
Our results showed that HSMF dose-dependently prevented the increase of systolic blood pressure and diastolic blood pressure induced by DOCA plus salt (DS) at 51-week-old mice. ...The protein expression of PKCalpha in the aorta was dose-dependently decreased by HSMF compar …
Our results showed that HSMF dose-dependently prevented the increase of systolic blood pressure and diastolic blood pressure induced …
LCI699, a potent 11beta-hydroxylase inhibitor, normalizes urinary cortisol in patients with Cushing's disease: results from a multicenter, proof-of-concept study.
Bertagna X, Pivonello R, Fleseriu M, Zhang Y, Robinson P, Taylor A, Watson CE, Maldonado M, Hamrahian AH, Boscaro M, Biller BM. Bertagna X, et al. J Clin Endocrinol Metab. 2014 Apr;99(4):1375-83. doi: 10.1210/jc.2013-2117. Epub 2013 Dec 11. J Clin Endocrinol Metab. 2014. PMID: 24423285 Clinical Trial.
INTRODUCTION: The clinical features and increased mortality associated with Cushing's syndrome result from a chronic excess of circulating cortisol. ...Mean 11-deoxycortisol, 11-deoxycorticosterone, and adrenocorticotropic hormone levels incr …
INTRODUCTION: The clinical features and increased mortality associated with Cushing's syndrome result from a chronic excess of …
Coexistence of different phenotypes in a family with glucocorticoid-remediable aldosteronism.
Fallo F, Pilon C, Williams TA, Sonino N, Morra Di Cella S, Veglio F, De Iasio R, Montanari P, Mulatero P. Fallo F, et al. J Hum Hypertens. 2004 Jan;18(1):47-51. doi: 10.1038/sj.jhh.1001636. J Hum Hypertens. 2004. PMID: 14688810
The father had normal blood pressure and potassium, low-normal PRA and normal aldosterone. All three subjects had elevated levels of urinary 18-hydroxycortisol and 18-oxocortisol. Baseline 11-deoxycorticosterone (DOC), corticosterone (B) and aldosteron …
The father had normal blood pressure and potassium, low-normal PRA and normal aldosterone. All three subjects had elevated levels of …
Hyperkalemic renal tubular acidosis: effect of furosemide in humans and in rats.
Rastogi S, Bayliss JM, Nascimento L, Arruda JA. Rastogi S, et al. Kidney Int. 1985 Nov;28(5):801-7. doi: 10.1038/ki.1985.201. Kidney Int. 1985. PMID: 4087694 Free article. Clinical Trial.
Furosemide increases urinary acidification in control subjects and in certain patients with normokalemic or hypokalemic distal renal tubular acidosis (RTA). ...Plasma aldosterone was variable in this group in that some patients had appropriate levels of aldos …
Furosemide increases urinary acidification in control subjects and in certain patients with normokalemic or hypokalemic distal …
Feminizing adrenocortical tumor: steroid hormone response to ketoconazole.
Saadi HF, Bravo EL, Aron DC. Saadi HF, et al. J Clin Endocrinol Metab. 1990 Feb;70(2):540-3. doi: 10.1210/jcem-70-2-540. J Clin Endocrinol Metab. 1990. PMID: 2298865
Serum estradiol levels decreased gradually over the 4-week course. Plasma aldosterone levels were essentially unaltered and 18-hydroxcorticosterone levels fell gradually, but there were marked increases in 11-deoxycorticosterone and corti …
Serum estradiol levels decreased gradually over the 4-week course. Plasma aldosterone levels were essentially unaltered and 18 …
Primary aldosteronism treated by trilostane (3 beta-hydroxysteroid dehydrogenase inhibitor).
Nakada T, Kazama T, Koike H, Yoshikawa M, Ishikawa S, Katayama T. Nakada T, et al. Urology. 1985 Feb;25(2):207-14. doi: 10.1016/0090-4295(85)90548-5. Urology. 1985. PMID: 2982227
The practicability and tolerability of trilostane, a competitive inhibitor of 3 beta-hydroxysteroid-delta 5-dehydrogenase, for the therapy of primary aldosteronism was assessed in 1 patient with aldosterone-producing adenoma (APA) and 3 subjects with idiopathic adrenal hyperplasi …
The practicability and tolerability of trilostane, a competitive inhibitor of 3 beta-hydroxysteroid-delta 5-dehydrogenase, for the therapy o …
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