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155 results

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Quoted phrase not found in phrase index: "Increased circulating IgM level"
Page 1
Current Understanding of Complement Proteins as Therapeutic Targets for the Treatment of Immunoglobulin A Nephropathy.
Rajasekaran A, Green TJ, Renfrow MB, Julian BA, Novak J, Rizk DV. Rajasekaran A, et al. Drugs. 2023 Nov;83(16):1475-1499. doi: 10.1007/s40265-023-01940-2. Epub 2023 Sep 25. Drugs. 2023. PMID: 37747686 Free PMC article. Review.
There is increasing clinical, biochemical, and genetic evidence that the complement system plays a paramount role in the pathogenesis of IgAN. ...Markers of complement activation via the lectin and alternative pathways in kidney-biopsy specimens are associated with disease …
There is increasing clinical, biochemical, and genetic evidence that the complement system plays a paramount role in the pathogenesis …
Circulating plasmablasts and high level of BAFF are hallmarks of minimal change nephrotic syndrome in adults.
Oniszczuk J, Beldi-Ferchiou A, Audureau E, Azzaoui I, Molinier-Frenkel V, Frontera V, Karras A, Moktefi A, Pillebout E, Zaidan M, El Karoui K, Delfau-Larue MH, Hénique C, Ollero M, Sahali D, Mahévas M, Audard V. Oniszczuk J, et al. Nephrol Dial Transplant. 2021 Mar 29;36(4):609-617. doi: 10.1093/ndt/gfaa279. Nephrol Dial Transplant. 2021. PMID: 33241414
Similarly, the increase of immunoglobulin M (IgM) and the decrease of IgG levels were significantly associated with the percentage of plasmablasts in MCNS-Rel patients (Spearman's rho = 0.36, P = 0.01 and Spearman's rho = -0.60, P = 0.01, respectively). ...CO …
Similarly, the increase of immunoglobulin M (IgM) and the decrease of IgG levels were significantly associated with the …
Suppression of normal immune responses after treatment with rituximab.
Kado R, Sanders G, McCune WJ. Kado R, et al. Curr Opin Rheumatol. 2016 May;28(3):251-8. doi: 10.1097/BOR.0000000000000272. Curr Opin Rheumatol. 2016. PMID: 27027812 Review.
Pre-existing hypogammaglobulinemia has been linked to increased risk of reduction of IgG levels and serious infections after rituximab therapy, and concomitant cyclophosphamide therapy has been associated with an increased risk of developing hypogammaglobulin …
Pre-existing hypogammaglobulinemia has been linked to increased risk of reduction of IgG levels and serious infections after r …
Increased serum IgM, immunodeficiency, and autoimmunity: A clinical series.
Picchianti Diamanti A, Rosado MM, Scarsella M, Ceccarelli S, Laganà B, D'Amelio R, Carsetti R. Picchianti Diamanti A, et al. Int J Immunopathol Pharmacol. 2015 Dec;28(4):547-56. doi: 10.1177/0394632015600231. Int J Immunopathol Pharmacol. 2015. PMID: 26526204 Free article.
RESULTS: Immunological and molecular analysis did not lead to the identification of known molecular defect typical of Hyper IgM syndrome. A comparative study of the peripheral blood B cell subsets between patients and healthy donors showed that in patients with auto …
RESULTS: Immunological and molecular analysis did not lead to the identification of known molecular defect typical of Hyper IgM syndr …
Expression of circulating Semaphorin3A and its association with inflammation and bone destruction in rheumatoid arthritis.
Gao H, Ma XX, Guo Q, Xie LF, Zhong YC, Zhang XW. Gao H, et al. Clin Rheumatol. 2018 Aug;37(8):2073-2080. doi: 10.1007/s10067-018-4070-x. Epub 2018 Apr 14. Clin Rheumatol. 2018. PMID: 29656374

Serum Sema3A of 130 RA patients (15.89 8.58 ng/ml) was significantly higher than that of 150 HC (6.96 2.62 ng/ml) and 215 patients with other rheumatic diseases (P < 0.05). Consistent with the serum level, the Sema3A mRNA level was also higher in RA patients' PBM

…
Serum Sema3A of 130 RA patients (15.89 8.58 ng/ml) was significantly higher than that of 150 HC (6.96 2.62 ng/ml) and 215 patients with othe …
Circulating microparticles in systemic Lupus Erythematosus.
Nielsen CT. Nielsen CT. Dan Med J. 2012 Nov;59(11):B4548. Dan Med J. 2012. PMID: 23171755 Free article. Review.
Observations of defective clearance of dying cells in SLE combined with the generation and exposure of nuclear autoantigens during apoptosis have led to the hypothesis that improperly cleared apoptotic debris constitutes a source of autoantigens capable of triggering autoimmune d …
Observations of defective clearance of dying cells in SLE combined with the generation and exposure of nuclear autoantigens during apoptosis …
Rituximab in patients with acute ST-elevation myocardial infarction: an experimental medicine safety study.
Zhao TX, Aetesam-Ur-Rahman M, Sage AP, Victor S, Kurian R, Fielding S, Ait-Oufella H, Chiu YD, Binder CJ, Mckie M, Hoole SP, Mallat Z. Zhao TX, et al. Cardiovasc Res. 2022 Feb 21;118(3):872-882. doi: 10.1093/cvr/cvab113. Cardiovasc Res. 2022. PMID: 33783498 Free PMC article. Clinical Trial.
The primary endpoint was safety, whilst secondary endpoints were changes in circulating immune cell subsets including B cells, and cardiac and inflammatory biomarkers. ...B-cell repopulation at 6 months was dose-dependent, with modulation of returning B-cell subsets. Immun …
The primary endpoint was safety, whilst secondary endpoints were changes in circulating immune cell subsets including B cells, and ca …
Idiopathic atrophie blanche.
Amato L, Chiarini C, Berti S, Massi D, Fabbri P. Amato L, et al. Skinmed. 2006 May-Jun;5(3):151-4. doi: 10.1111/j.1540-9740.2006.04541.x. Skinmed. 2006. PMID: 16687988 Review.
Laboratory investigations were normal or negative, including complete blood cell count, platelets, coagulation indexes, erythrocyte sedimentation rate, serum immunoglobulins, antinuclear antibodies, anti-double-stranded DNA, anticardiolipin, antiphospholipids, antineutroph …
Laboratory investigations were normal or negative, including complete blood cell count, platelets, coagulation indexes, erythrocyte s …
Serological and molecular epidemiology of the Dengue, Zika and Chikungunya viruses in a risk area in Brazil.
Mota ML, Dos Santos Souza Marinho R, Duro RLS, Hunter J, de Menezes IRA, de Lima Silva JMF, Pereira GLT, Sabino EC, Grumach A, Diaz RS, do Socorro Lucena M, Komninakis SV. Mota ML, et al. BMC Infect Dis. 2021 Jul 24;21(1):704. doi: 10.1186/s12879-021-06401-3. BMC Infect Dis. 2021. PMID: 34303348 Free PMC article.
BACKGROUND: The co-circulation of types of arbovirus in areas where they are endemic increased the risk of outbreaks and limited the diagnostic methods available. ...The prevalence of IgM/IgG antibodies and of infections confirmed by RT-qPCR were presented wi …
BACKGROUND: The co-circulation of types of arbovirus in areas where they are endemic increased the risk of outbreaks and limit …
A Comparison of the Circulating Endocan Levels between the Inflammatory and Malignant Diseases of the Same Organ: The Breast.
Basim P, Argun D. Basim P, et al. J Invest Surg. 2021 Nov;34(11):1207-1213. doi: 10.1080/08941939.2020.1792008. Epub 2020 Jul 14. J Invest Surg. 2021. PMID: 32660374
No significant distinctive difference was observed between the BC and IGM groups in terms of the endocan level (p = 0.373). The serum endocan level was found to be positively correlated with BMI and vitamin D levels in the BC group (p = 0.043 and p = 0 …
No significant distinctive difference was observed between the BC and IGM groups in terms of the endocan level (p = 0.373). Th …
155 results