Postprandial metabolism of apolipoproteins B48, B100, C-III, and E in humans with APOC3 loss-of-function mutations.
Taskinen MR, Björnson E, Matikainen N, Söderlund S, Rämö J, Ainola MM, Hakkarainen A, Sihlbom C, Thorsell A, Andersson L, Bergh PO, Henricsson M, Romeo S, Adiels M, Ripatti S, Laakso M, Packard CJ, Borén J.
Taskinen MR, et al.
JCI Insight. 2022 Oct 10;7(19):e160607. doi: 10.1172/jci.insight.160607.
JCI Insight. 2022.
PMID: 36040803
Free PMC article.
Clinical Trial.
Studies were conducted in the postprandial state to provide a more comprehensive view of the influence of this protein on TG transport.ResultsCompared with non-LOF variant participants, a genetically determined decrease in apoC-III resulted in marked acceleration of lipolysis of …
Studies were conducted in the postprandial state to provide a more comprehensive view of the influence of this protein on TG transport.Resul …