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Quoted phrase not found in phrase index: "Increased circulating creatine kinase MM isoform"
Page 1
The specificity of biochemical markers of cardiac damage: a problem solved.
Apple FS. Apple FS. Clin Chem Lab Med. 1999 Nov-Dec;37(11-12):1085-9. doi: 10.1515/CCLM.1999.158. Clin Chem Lab Med. 1999. PMID: 10726816 Review.
This paper reviews the tissue specificity of cardiac troponin I (cTnl), cardiac troponin T (cTnT) and creatine kinase (CK) MB in human and animal heart and skeletal muscles. ...Representative cases are described demonstrating the role of monitoring cardiac troponins …
This paper reviews the tissue specificity of cardiac troponin I (cTnl), cardiac troponin T (cTnT) and creatine kinase (CK) MB …
Diagnostic use of CK-MM and CK-MB isoforms for detecting myocardial infarction.
Apple FS. Apple FS. Clin Lab Med. 1989 Dec;9(4):643-54. Clin Lab Med. 1989. PMID: 2686906 Review.
Recently reports have appeared describing numerous serum and plasma CK-MM and CK-MB isoform patterns after AMI. Following release from injured myocardium CK-MM3 and CK-MB2 (designated the tissue isoforms) are converted in the circulation to post-translation p …
Recently reports have appeared describing numerous serum and plasma CK-MM and CK-MB isoform patterns after AMI. Following release fro …
Cardiac Energetics in Patients With Aortic Stenosis and Preserved Versus Reduced Ejection Fraction.
Peterzan MA, Clarke WT, Lygate CA, Lake HA, Lau JYC, Miller JJ, Johnson E, Rayner JJ, Hundertmark MJ, Sayeed R, Petrou M, Krasopoulos G, Srivastava V, Neubauer S, Rodgers CT, Rider OJ. Peterzan MA, et al. Circulation. 2020 Jun 16;141(24):1971-1985. doi: 10.1161/CIRCULATIONAHA.119.043450. Epub 2020 May 22. Circulation. 2020. PMID: 32438845 Free PMC article.
BACKGROUND: Why some but not all patients with severe aortic stenosis (SevAS) develop otherwise unexplained reduced systolic function is unclear. We investigate the hypothesis that reduced creatine kinase (CK) capacity and flux is associated with this transition. .. …
BACKGROUND: Why some but not all patients with severe aortic stenosis (SevAS) develop otherwise unexplained reduced systolic function is unc …
The liver and blood cells are responsible for creatine kinase clearance in blood Circulation: A retrospective study among different human diseases.
Pan N, Wu Y, Yang B, Zhang M, He Y, Wang Z, Tan L, Zhang L. Pan N, et al. Clin Chim Acta. 2023 Apr 1;544:117335. doi: 10.1016/j.cca.2023.117335. Epub 2023 Apr 8. Clin Chim Acta. 2023. PMID: 37037296
BACKGROUND: Muscle damage leads to increased serum creatine kinase (CK) levels in diseases such as acute myocardial infarction. ...CONCLUSIONS: We proposed that the liver and blood cells were mainly responsible for CK clearance in blood circu …
BACKGROUND: Muscle damage leads to increased serum creatine kinase (CK) levels in diseases such as acute myocardial inf …
The earliest diagnosis of acute myocardial infarction.
Rozenman Y, Gotsman MS. Rozenman Y, et al. Annu Rev Med. 1994;45:31-44. doi: 10.1146/annurev.med.45.1.31. Annu Rev Med. 1994. PMID: 8198386 Review.
Time-consuming perfusion nuclear studies are inferior to echocardiography but may nevertheless enable physicians to diagnose myocardial infarction in the emergency room. Although the presence of excess creatine kinase is a sign of myocardial necrosis, its increas …
Time-consuming perfusion nuclear studies are inferior to echocardiography but may nevertheless enable physicians to diagnose myocardial infa …
Creatine kinase isoforms as circulating markers of deterioration in idiopathic dilated cardiomyopathy.
Hossein-Nia M, Baig K, Goldman JH, Keeling PJ, Caforio AL, Holt DW, McKenna WJ. Hossein-Nia M, et al. Clin Cardiol. 1997 Jan;20(1):55-60. doi: 10.1002/clc.4960200112. Clin Cardiol. 1997. PMID: 8994739 Free PMC article.
To obtain an objective assessment of myocardial damage in DCM, we measured plasma levels of creatine kinase (CK), its isoenzymes (CK-MM and CK-MB), and separated the isoforms of CK-MM and CK-MB. ...Thus, CK measurements, in particular CK-MB isoforms, a …
To obtain an objective assessment of myocardial damage in DCM, we measured plasma levels of creatine kinase (CK), its isoenzym …
Elevation of serum creatine phosphokinase and its MB isoenzyme during normal labor and early puerperium.
Abramov Y, Abramov D, Abrahamov A, Durst R, Schenker J. Abramov Y, et al. Acta Obstet Gynecol Scand. 1996 Mar;75(3):255-60. doi: 10.3109/00016349609047097. Acta Obstet Gynecol Scand. 1996. PMID: 8607339 Clinical Trial.
RESULTS: All women were found to have low to normal antepartum serum enzymes levels. However, during labor total creatine phosphokinase increased markedly, reaching a peak of 2-4 fold baseline levels 24 hours postpartum. ...Serum lactate dehydrogenase and aspartate …
RESULTS: All women were found to have low to normal antepartum serum enzymes levels. However, during labor total creatine phosphokina …
Downregulation of miR-483-5p decreases hypoxia-induced injury in human cardiomyocytes by targeting MAPK3.
Hao Y, Yuan H, Yu H. Hao Y, et al. Cell Mol Biol Lett. 2020 Mar 17;25:20. doi: 10.1186/s11658-020-00213-0. eCollection 2020. Cell Mol Biol Lett. 2020. PMID: 32206064 Free PMC article. Retracted.
RESULTS: The expression levels of miR-483-5p were significantly higher in AMI patients than in control subjects. Circulating levels of miR-483-5p positively correlated with creatine kinase MB isoform (CK-MB) and cardiac troponin I (cTnI) levels. The in …
RESULTS: The expression levels of miR-483-5p were significantly higher in AMI patients than in control subjects. Circulating levels o …
Evaluation of myocardial infarction with enzymatic indices.
Ahumada G, Roberts R, Sobel BE. Ahumada G, et al. Prog Cardiovasc Dis. 1976 Mar-Apr;18(5):405-20. doi: 10.1016/0033-0620(76)90004-9. Prog Cardiovasc Dis. 1976. PMID: 775531 Review.
Physiologically based models of processes affecting appearance and disappearance of CPK from the circulation may improve predictions and estimates of infarct size. Elevation of serum MB CPK isoenzyme activity appears to be a highly sensitive and specific indicator of myoca …
Physiologically based models of processes affecting appearance and disappearance of CPK from the circulation may improve predictions …
Nature and time course of generation of isoforms of creatine kinase, MB fraction in vivo.
Prager NA, Suzuki T, Jaffe AS, Sobel BE, Abendschein DR. Prager NA, et al. J Am Coll Cardiol. 1992 Aug;20(2):414-9. doi: 10.1016/0735-1097(92)90111-y. J Am Coll Cardiol. 1992. PMID: 1634680 Free article.
OBJECTIVES: This study was designed to characterize the nature and time course of carboxy-terminal lysine cleavages from the tissue isoform of MB creatine kinase (CK) in vivo. BACKGROUND: Rapid conversion of the tissue isoform of MM CK to two additiona …
OBJECTIVES: This study was designed to characterize the nature and time course of carboxy-terminal lysine cleavages from the tissue isofo …
55 results