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Quoted phrase not found in phrase index: "Increased circulating interleukin 12 concentration"
Page 1
Ustekinumab Decreases Circulating Th17 Cells in Ulcerative Colitis.
Imazu N, Torisu T, Ihara Y, Umeno J, Kawasaki K, Fujioka S, Fuyuno Y, Matsuno Y, Moriyama T, Kitazono T. Imazu N, et al. Intern Med. 2024 Jan 15;63(2):153-158. doi: 10.2169/internalmedicine.1724-23. Epub 2023 May 17. Intern Med. 2024. PMID: 37197955 Free PMC article.
Objective T helper (Th) cells play a central role in the pathogenesis of ulcerative colitis (UC). The present study analyzed the changes in circulating T cells by administration of ustekinumab (UST), an interleukin-12/23p40 antibody. ...Patients We evaluated …
Objective T helper (Th) cells play a central role in the pathogenesis of ulcerative colitis (UC). The present study analyzed the changes in …
Exhaustive exercise and type-1/type-2 cytokine balance with special focus on interleukin-12 p40/p70.
Suzuki K, Nakaji S, Kurakake S, Totsuka M, Sato K, Kuriyama T, Fujimoto H, Shibusawa K, Machida K, Sugawara K. Suzuki K, et al. Exerc Immunol Rev. 2003;9:48-57. Exerc Immunol Rev. 2003. PMID: 14686094 Review.

Conversely, plasma IL-12 p70 could not be detected even using two different assays. The marathon race caused a marked increase in the plasma concentrations of IL-6 and IL-10. Their responses were correlated (r = 0.78, p < 0.01), indicating that IL-6 is an inducer

…
Conversely, plasma IL-12 p70 could not be detected even using two different assays. The marathon race caused a marked increase in the …
Increased IFN-gamma-producing Th17/Th1 cells and their association with lung function and current smoking status in patients with chronic obstructive pulmonary disease.
Xu W, Li R, Sun Y. Xu W, et al. BMC Pulm Med. 2019 Jul 26;19(1):137. doi: 10.1186/s12890-019-0899-2. BMC Pulm Med. 2019. PMID: 31349846 Free PMC article.
METHODS: Blood samples were obtained from 21 never-smokers, 31 smokers with normal lung function and 83 patients with COPD. ...The associations of Th17/Th1 cells with lung function and smoking were evaluated. RESULTS: In peripheral blood, significantly increased …
METHODS: Blood samples were obtained from 21 never-smokers, 31 smokers with normal lung function and 83 patients with COPD. ...The as …
Relationship Between Serum IL-12 and p40 Subunit Concentrations and Lipid Parameters in Overweight and Obese Women.
Nikołajuk A, Karczewska-Kupczewska M, Straczkowski M. Nikołajuk A, et al. Metab Syndr Relat Disord. 2015 Oct;13(8):336-42. doi: 10.1089/met.2014.0164. Epub 2015 Jun 3. Metab Syndr Relat Disord. 2015. PMID: 26038987
Recent findings indicate that IL-12 could be involved in the development of obesity-associated co-morbidities, especially atherosclerosis. It is unclear if there are alternations in circulating concentrations of total IL-12 and its subunit p40 in young subjects with …
Recent findings indicate that IL-12 could be involved in the development of obesity-associated co-morbidities, especially atherosclerosis. I …
Galectin-3 and aldosterone as potential tandem biomarkers in pulmonary arterial hypertension.
Calvier L, Legchenko E, Grimm L, Sallmon H, Hatch A, Plouffe BD, Schroeder C, Bauersachs J, Murthy SK, Hansmann G. Calvier L, et al. Heart. 2016 Mar;102(5):390-6. doi: 10.1136/heartjnl-2015-308365. Heart. 2016. PMID: 26869635
BACKGROUND: Several studies have identified circulating biomarkers to be associated with the presence and severity of pulmonary arterial hypertension (PAH). ...The vascular injury marker intercellular adhesion molecule 1 (ICAM-1) was increased in IPAH and PAH-CTD ve …
BACKGROUND: Several studies have identified circulating biomarkers to be associated with the presence and severity of pulmonary arter …
Phase II clinical trial of interleukin-12 in patients with relapsed and refractory non-Hodgkin's lymphoma and Hodgkin's disease.
Younes A, Pro B, Robertson MJ, Flinn IW, Romaguera JE, Hagemeister F, Dang NH, Fiumara P, Loyer EM, Cabanillas FF, McLaughlin PW, Rodriguez MA, Samaniego F. Younes A, et al. Clin Cancer Res. 2004 Aug 15;10(16):5432-8. doi: 10.1158/1078-0432.CCR-04-0540. Clin Cancer Res. 2004. PMID: 15328181 Clinical Trial.
Treatment was well tolerated, and the most common toxicity was flu-like symptoms. Reversible grade 3 hepatic toxicity was observed in three patients requiring dose reduction. IL-12 therapy increased the median number of peripheral blood CD8 T lymphocytes from …
Treatment was well tolerated, and the most common toxicity was flu-like symptoms. Reversible grade 3 hepatic toxicity was observed in …
Circulating cytokines and hormones with immunosuppressive but neutrophil-priming potentials rise after endurance exercise in humans.
Suzuki K, Yamada M, Kurakake S, Okamura N, Yamaya K, Liu Q, Kudoh S, Kowatari K, Nakaji S, Sugawara K. Suzuki K, et al. Eur J Appl Physiol. 2000 Mar;81(4):281-7. doi: 10.1007/s004210050044. Eur J Appl Physiol. 2000. PMID: 10664086
Furthermore, concentrations of IL-1 receptor antagonist (IL-1ra) and IL-6, which are negative-feedback inhibitors of cytokine production, increased by more than 100 times. As for humoral mediators of neutrophil mobilization, concentrations of growth hormone ( …
Furthermore, concentrations of IL-1 receptor antagonist (IL-1ra) and IL-6, which are negative-feedback inhibitors of cytokine product …
Changes in circulating dendritic cells and IL-12 in relation to the angiogenic factor VEGF during IL-2 immunotherapy of metastatic renal cell cancer.
Bonfanti A, Lissoni P, Bucovec R, Rovelli F, Brivio F, Fumagalli L. Bonfanti A, et al. Int J Biol Markers. 2000 Apr-Jun;15(2):161-4. doi: 10.1177/172460080001500206. Int J Biol Markers. 2000. PMID: 10883890 Free article.
Finally, a significant increase in the mean number of circulating mature DCs occurred only in patients with PR or SD, whereas no significant change was seen in patients with PD. By contrast, no significant change was observed in the mean number of immature DC …
Finally, a significant increase in the mean number of circulating mature DCs occurred only in patients with PR or SD, whereas …
Alterations in cytokines and haematological parameters during the acute and convalescent phases of Plasmodium falciparum and Plasmodium vivax infections.
Rodrigues-da-Silva RN, Lima-Junior Jda C, Fonseca Bde P, Antas PR, Baldez A, Storer FL, Santos F, Banic DM, Oliveira-Ferreira Jd. Rodrigues-da-Silva RN, et al. Mem Inst Oswaldo Cruz. 2014 Apr;109(2):154-62. doi: 10.1590/0074-0276140275. Epub 2014 Mar 4. Mem Inst Oswaldo Cruz. 2014. PMID: 24676654 Free PMC article.
During the acute phase, thrombocytopaenia, eosinopaenia, lymphopaenia and an increased number of band cells were observed in the majority of the patients. ...Plasma IL-10 concentration was positively correlated with parasitaemia in P. vivax and P. falciparum- …
During the acute phase, thrombocytopaenia, eosinopaenia, lymphopaenia and an increased number of band cells were observed in t …
Abnormally enhanced blood concentrations of vascular endothelial growth factor (VEGF) in metastatic cancer patients and their relation to circulating dendritic cells, IL-12 and endothelin-1.
Lissoni P, Malugani F, Bonfanti A, Bucovec R, Secondino S, Brivio F, Ferrari-Bravo A, Ferrante R, Vigoré L, Rovelli F, Mandalà M, Viviani S, Fumagalli L, Gardani GS. Lissoni P, et al. J Biol Regul Homeost Agents. 2001 Apr-Jun;15(2):140-4. J Biol Regul Homeost Agents. 2001. PMID: 11501971
Elevated VEGF blood concentrations have been proven to be associated with poor prognosis in human neoplasms. ...Mean serum levels of VEGF-165 were significantly higher in metastatic patients than in controls or in non-metastatic patients, whereas the total amounts o …
Elevated VEGF blood concentrations have been proven to be associated with poor prognosis in human neoplasms. ...Mean serum lev …
16 results