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196 results

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Quoted phrase not found in phrase index: "Increased proportion of HLA DR+ T cells"
Page 1
Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning.
Wang J, Kang Z, Liu Y, Li Z, Liu Y, Liu J. Wang J, et al. Front Immunol. 2022 Sep 23;13:956078. doi: 10.3389/fimmu.2022.956078. eCollection 2022. Front Immunol. 2022. PMID: 36211422 Free PMC article.
RESULTS: A significant difference in immune cell infiltration was observed between unstable and stable plaques. The proportions of M0, M1, and M2 macrophages were significantly higher and that of CD8(+) T cells and NK cells were significantly lower in …
RESULTS: A significant difference in immune cell infiltration was observed between unstable and stable plaques. The proportions …
Phenotypic and functional characteristics of HLA-DR(+) neutrophils in Brazilians with cutaneous leishmaniasis.
Davis RE, Sharma S, Conceição J, Carneiro P, Novais F, Scott P, Sundar S, Bacellar O, Carvalho EM, Wilson ME. Davis RE, et al. J Leukoc Biol. 2017 Mar;101(3):739-749. doi: 10.1189/jlb.4A0915-442RR. Epub 2016 Oct 17. J Leukoc Biol. 2017. PMID: 28076241 Free PMC article.
Compared with conventional PMNs, HLA-DR(+) PMNs showed increased activation, degranulation, DHR123 oxidation, and phagocytic capacity. A few HLA-DR(+) PMNs were observed in healthy subjects, and that proportion could be increase …
Compared with conventional PMNs, HLA-DR(+) PMNs showed increased activation, degranulation, DHR123 oxidation, and phago …
Circulating immune cell landscape and T-cell abnormalities in patients with moyamoya disease.
Ge P, Tao C, Wang W, He Q, Liu C, Zheng Z, Mou S, Zhang B, Liu X, Zhang Q, Wang R, Li H, Zhang D, Zhao J. Ge P, et al. Clin Transl Med. 2024 Apr;14(4):e1647. doi: 10.1002/ctm2.1647. Clin Transl Med. 2024. PMID: 38566524 Free PMC article.
MMD was also linked to heightened immune activation, as evidenced by elevated expression levels of HLA-DR and p-STAT3. CONCLUSIONS: Our findings offer a comprehensive view of the circulating immune cell landscape in MMD patients. Immune dysregulation in patients wit …
MMD was also linked to heightened immune activation, as evidenced by elevated expression levels of HLA-DR and p-STAT3. CONCLUS …
A profile of TNFR2(+) regulatory T cells and CD103(+) dendritic cells in the peripheral blood of patients with asthma.
Azid NA, Ahmad S, Boer JC, Al-Hatamleh MAI, Mohammad N, Mohd Ashari NS, Tan HT, Chen X, Plebanski M, Mohamud R. Azid NA, et al. Hum Immunol. 2020 Oct-Nov;81(10-11):634-643. doi: 10.1016/j.humimm.2020.07.006. Epub 2020 Aug 6. Hum Immunol. 2020. PMID: 32771274
We observed lower trends of CD11b(-)CD103(+) DCs and CD86 within CD11b(-)CD103(+) DCs, while increased levels of Foxp3 expressing CD25(+/-)TNFR2(+) cells in asthmatics. There was a positive correlation in the expression of Foxp3 within CD3(+)CD4(+)CD25(+)TNFR2(+) Tr …
We observed lower trends of CD11b(-)CD103(+) DCs and CD86 within CD11b(-)CD103(+) DCs, while increased levels of Foxp3 express …
The treatment of psoriasis with IL-10: rationale and review of the first clinical trials.
Asadullah K, Döcke WD, Sabat RV, Volk HD, Sterry W. Asadullah K, et al. Expert Opin Investig Drugs. 2000 Jan;9(1):95-102. doi: 10.1517/13543784.9.1.95. Expert Opin Investig Drugs. 2000. PMID: 11060663 Review.
In psoriasis, a common cutaneous immune disease, a relative deficiency in cutaneous IL-10 expression is observed. Several lines of evidence suggest that IL-10 could have antipsoriatic abilities. ...The therapy was well-tolerated and clinical efficiency was found in the maj …
In psoriasis, a common cutaneous immune disease, a relative deficiency in cutaneous IL-10 expression is observed. Several lines of ev …
Activated CD8+CD38+ Cells Are Associated With Worse Clinical Outcome in Hospitalized COVID-19 Patients.
Bobcakova A, Barnova M, Vysehradsky R, Petriskova J, Kocan I, Diamant Z, Jesenak M. Bobcakova A, et al. Front Immunol. 2022 Mar 14;13:861666. doi: 10.3389/fimmu.2022.861666. eCollection 2022. Front Immunol. 2022. PMID: 35392095 Free PMC article.
Examined parameters included the differential blood cell counts, various parameters of cellular and humoral immunity (serum concentration of immunoglobulins, C4 and C3), lymphocyte subsets (CD3(+), CD4(+), CD8(+), CD19(+), NK cells, CD4(+)CD45RO(+)), expression of activation ( …
Examined parameters included the differential blood cell counts, various parameters of cellular and humoral immunity (serum concentration of …
Vitamin D modulates the expression of HLA-DR and CD38 after in vitro activation of T-cells.
Villegas-Ospina S, Aguilar-Jimenez W, Gonzalez SM, Rugeles MT. Villegas-Ospina S, et al. Horm Mol Biol Clin Investig. 2017 Mar 1;29(3):93-103. doi: 10.1515/hmbci-2016-0037. Horm Mol Biol Clin Investig. 2017. PMID: 28222027
As co-expression, it increased the CD38+HLA-DR- and decreased CD38-HLA-DR+ subpopulations in both CD4+ and CD8+ T-cells, and decreased CD4+CD38-HLA-DR- and CD8+ CD38+HLA-DR+; whereas both calcidiol conce …
As co-expression, it increased the CD38+HLA-DR- and decreased CD38-HLA-DR+ subpopulations in both CD4+ an …
Clinical outcome following checkpoint therapy in renal cell carcinoma is associated with a burst of activated CD8 T cells in blood.
Carlisle JW, Jansen CS, Cardenas MA, Sobierajska E, Reyes AM, Greenwald R, Del Balzo L, Prokhnevska N, Kucuk O, Carthon BC, Mullane PC, Osunkoya A, Baumgarten D, Hosseinzadeh F, Wilkinson S, Lake R, Sowalsky AG, Liu Y, Master VA, Bilen MA, Kissick H. Carlisle JW, et al. J Immunother Cancer. 2022 Jul;10(7):e004803. doi: 10.1136/jitc-2022-004803. J Immunother Cancer. 2022. PMID: 35863822 Free PMC article.
RESULTS: We found that a small proportion of CD4 and CD8 T cells in the blood activate following checkpoint therapy, expressing the proliferation marker Ki67 and activation markers HLA-DR and CD38. Patients who had the highest increase in …
RESULTS: We found that a small proportion of CD4 and CD8 T cells in the blood activate following checkpoint therapy, ex …
Cytotoxic NK cells phenotype and activated lymphocytes are the main characteristics of patients with alcohol-associated liver disease.
Zurera-Egea C, Teniente-Serra A, Fuster D, Martínez-Cáceres E, Muga R, Zuluaga P. Zurera-Egea C, et al. Clin Exp Med. 2023 Nov;23(7):3539-3547. doi: 10.1007/s10238-023-01121-1. Epub 2023 Jul 1. Clin Exp Med. 2023. PMID: 37392250 Free PMC article.
Totally, 79 patients (51-years, 71% males) were admitted to treatment of AUD. ALF was defined as FIB4-score > 2.67. Immunophenotyping of NK cells (CD3(-)CD56(+)CD16(+), CD3(-)CD56(+)CD16(-), CD3(-)CD56(-)CD16(+)), NKT-like (CD3(+)CD56(+)), and the activation status of C …
Totally, 79 patients (51-years, 71% males) were admitted to treatment of AUD. ALF was defined as FIB4-score > 2.67. Immunophenotyp …
Role of the appendix in the pathogenesis of ulcerative colitis.
Matsushita M, Uchida K, Okazaki K. Matsushita M, et al. Inflammopharmacology. 2007 Aug;15(4):154-7. doi: 10.1007/s10787-007-1563-7. Inflammopharmacology. 2007. PMID: 17701017 Review.
In the appendix of UC patients, the CD4/CD8 ratio is significantly increased, and the proportion of CD4+CD69+ (early activation antigen) T cells, but not of CD4+HLA-DR+ (mature activation antigen) T cells, is also significan …
In the appendix of UC patients, the CD4/CD8 ratio is significantly increased, and the proportion of CD4+CD69+ (early activatio …
196 results