Effect of incubation with crystalloid solutions or medications on packed red blood cells.
Mladinov D, Yarnoff K, Nagababu E, Berkowitz DE, Lawrence C, Ness PM, Kickler T, Brunker PA, Boyd JS, Dodd-O JM.
Mladinov D, et al.
Transfusion. 2019 Aug;59(8):2643-2651. doi: 10.1111/trf.15353. Epub 2019 May 28.
Transfusion. 2019.
PMID: 31135973
CONCLUSION: Our data suggest that 5 minutes of PRBC incubation with isotonic crystalloids or catecholamines does not deleteriously alter PRBC hemolysis, membrane deformability, or aggregation. Co-incubation with D5W likely increases hemolysis. Propofol may pr …
CONCLUSION: Our data suggest that 5 minutes of PRBC incubation with isotonic crystalloids or catecholamines does not deleteriously alter PRB …