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164 results

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Quoted phrase not found in phrase index: "Increased susceptibility to B-cell lymphoma"
Page 1
A Deep Insight Into CAR-T Cell Therapy in Non-Hodgkin Lymphoma: Application, Opportunities, and Future Directions.
Marofi F, Rahman HS, Achmad MH, Sergeevna KN, Suksatan W, Abdelbasset WK, Mikhailova MV, Shomali N, Yazdanifar M, Hassanzadeh A, Ahmadi M, Motavalli R, Pathak Y, Izadi S, Jarahian M. Marofi F, et al. Front Immunol. 2021 Jun 23;12:681984. doi: 10.3389/fimmu.2021.681984. eCollection 2021. Front Immunol. 2021. PMID: 34248965 Free PMC article. Retracted. Review.
NHL subtypes include marginal zone lymphoma, small lymphocytic lymphoma, follicular lymphoma (FL), and lymphoplasmacytic lymphoma. ...One of the promising therapy methods involved in the triumph of immunotherapy is the chimeric antigen receptor (CAR) T …
NHL subtypes include marginal zone lymphoma, small lymphocytic lymphoma, follicular lymphoma (FL), and lymphoplasmacyti …
Pediatric Extranodal Lymphoma.
Chung EM, Pavio M. Chung EM, et al. Radiol Clin North Am. 2016 Jul;54(4):727-46. doi: 10.1016/j.rcl.2016.03.004. Radiol Clin North Am. 2016. PMID: 27265605 Review.
Compared with adults, this histologic spectrum of pediatric NHL is very narrow and consists of aggressive tumors. Patients typically present with widespread disease. Generally, NHL occurring in children includes Burkitt lymphoma, lymphoblastic lymphoma, diffu …
Compared with adults, this histologic spectrum of pediatric NHL is very narrow and consists of aggressive tumors. Patients typically present …
AIDS lymphomas.
Middleton GW, Lau RK. Middleton GW, et al. Int J STD AIDS. 1992 May-Jun;3(3):173-81. doi: 10.1177/095646249200300304. Int J STD AIDS. 1992. PMID: 1616963
Chronically immunosuppressed individuals are susceptible to lymphoreticular tumors. Up to 15% of patients with congenital deficiencies such as ataxia=telangiectasia may develop malignancies, mainly high-grade B cell non=Hodgkin's lymphomas (NHLs). ...Interleu …
Chronically immunosuppressed individuals are susceptible to lymphoreticular tumors. Up to 15% of patients with congenital deficiencie …
Common Variable Immunodeficiency.
Saikia B, Gupta S. Saikia B, et al. Indian J Pediatr. 2016 Apr;83(4):338-44. doi: 10.1007/s12098-016-2038-x. Epub 2016 Feb 12. Indian J Pediatr. 2016. PMID: 26868026 Review.
Patients, in addition to frequent sino-pulmonary infections, are also susceptible to various autoimmune diseases and malignancy, predominantly lymphoma and leukemia. ...A number of gene mutations have been described in CVID; however, these genetic alterations accoun …
Patients, in addition to frequent sino-pulmonary infections, are also susceptible to various autoimmune diseases and malignancy, pred …
The routes for transformation of follicular lymphoma.
Okosun J, Montoto S, Fitzgibbon J. Okosun J, et al. Curr Opin Hematol. 2016 Jul;23(4):385-91. doi: 10.1097/MOH.0000000000000255. Curr Opin Hematol. 2016. PMID: 27135979 Review.
PURPOSE OF REVIEW: Aggressive transformation, a frequent event in the natural history of follicular lymphoma, is associated with increased lymphoma-related mortality and yet the underlying biology remains poorly defined. ...Although the majority of tFLs maint …
PURPOSE OF REVIEW: Aggressive transformation, a frequent event in the natural history of follicular lymphoma, is associated with i
Immunoglobulins and Transcription Factors in Otitis Media.
Jung SY, Kim D, Park DC, Lee EH, Choi YS, Ryu J, Kim SH, Yeo SG. Jung SY, et al. Int J Mol Sci. 2021 Mar 21;22(6):3201. doi: 10.3390/ijms22063201. Int J Mol Sci. 2021. PMID: 33801155 Free PMC article. Review.
Moreover, IgG, IgA, and IgM concentrations in the middle ear cavity are increased during immune responses in patients with otitis media. B cell leukemia/lymphoma-6 (Bcl-6) and paired box gene 5 (Pax-5) suppress antibody production, whereas B lymphocyte …
Moreover, IgG, IgA, and IgM concentrations in the middle ear cavity are increased during immune responses in patients with otitis med …
The Function of MicroRNAs in B-Cell Development, Lymphoma, and Their Potential in Clinical Practice.
Zheng B, Xi Z, Liu R, Yin W, Sui Z, Ren B, Miller H, Gong Q, Liu C. Zheng B, et al. Front Immunol. 2018 Apr 30;9:936. doi: 10.3389/fimmu.2018.00936. eCollection 2018. Front Immunol. 2018. PMID: 29760712 Free PMC article. Review.
We list and describe several examples to illustrate miRNAs' role in the development of B-cell lymphoma, both as oncogenes and tumor suppressor genes. Finally, we delineate the potential value of miRNAs in diagnosing B-cell lymphoma, predi …
We list and describe several examples to illustrate miRNAs' role in the development of B-cell lymphoma, both as oncogen …
The Role of PI3K Inhibition in Lymphoid Malignancies.
von Keudell G, Moskowitz AJ. von Keudell G, et al. Curr Hematol Malig Rep. 2019 Oct;14(5):405-413. doi: 10.1007/s11899-019-00540-w. Curr Hematol Malig Rep. 2019. PMID: 31359259 Review.
In this article, we will provide an overview over the role PI3-kinase signalling, one of the most important dysregulated pathways in cancer, and its successful inhibition in lymphoma. RECENT FINDINGS: PI3-kinase inhibitors have shown remarkable activity in an increasing
In this article, we will provide an overview over the role PI3-kinase signalling, one of the most important dysregulated pathways in cancer, …
The SKP2-p27 axis defines susceptibility to cell death upon CHK1 inhibition.
Lohmüller M, Roeck BF, Szabo TG, Schapfl MA, Pegka F, Herzog S, Villunger A, Schuler F. Lohmüller M, et al. Mol Oncol. 2022 Aug;16(15):2771-2787. doi: 10.1002/1878-0261.13264. Epub 2022 Jul 7. Mol Oncol. 2022. PMID: 35673965 Free PMC article.
Cancer cells deficient in p53 tumor suppressor function reportedly develop a strong dependency on CHK1 for proper cell cycle progression and maintenance of genome integrity, sparking interest in developing kinase inhibitors. Pharmacological inhibition of CHK1 triggers B- …
Cancer cells deficient in p53 tumor suppressor function reportedly develop a strong dependency on CHK1 for proper cell cycle progression and …
Hairy cell leukemia: present and future directions.
Kreitman RJ. Kreitman RJ. Leuk Lymphoma. 2019 Dec;60(12):2869-2879. doi: 10.1080/10428194.2019.1608536. Epub 2019 May 9. Leuk Lymphoma. 2019. PMID: 31068044 Free PMC article. Review.
Hairy cell leukemia (HCL) is an indolent B-cell malignancy, with long-term responses to purine analogs, but with decreasing efficacy and increasing toxicity with repeated courses. ...A molecularly defined IGHV4-34+ variant is also resistant whether HCL or HCL …
Hairy cell leukemia (HCL) is an indolent B-cell malignancy, with long-term responses to purine analogs, but with decreasing ef …
164 results