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Quoted phrase not found in phrase index: "Increased susceptibility to fractures"
Page 1
Hypophosphatasia.
Fenn JS, Lorde N, Ward JM, Borovickova I. Fenn JS, et al. J Clin Pathol. 2021 Oct;74(10):635-640. doi: 10.1136/jclinpath-2021-207426. Epub 2021 Apr 30. J Clin Pathol. 2021. PMID: 33931563 Review.
It is caused by a mutation in the ALPL gene encoding the tissue-non-specific isoenzyme of ALP (TNSALP) resulting in a loss of function. The disease is highly heterogenous in its clinical expression ranging from stillbirth without mineralised bone to the mild form of …
It is caused by a mutation in the ALPL gene encoding the tissue-non-specific isoenzyme of ALP (TNSALP) resulting in a loss of function. The …
Present status and future directions: vertical root fractures in root filled teeth.
Patel S, Bhuva B, Bose R. Patel S, et al. Int Endod J. 2022 May;55 Suppl 3(Suppl 3):804-826. doi: 10.1111/iej.13737. Epub 2022 Apr 15. Int Endod J. 2022. PMID: 35338655 Free PMC article. Review.
Vertical root fracture (VRF) is a common reason for the extraction of root filled teeth. ...However, an understanding of the aetiology of VRFs, and more importantly, the key predisposing factors, is crucial in identifying teeth that may be susceptible. Thorough clin …
Vertical root fracture (VRF) is a common reason for the extraction of root filled teeth. ...However, an understanding of the aetiolog …
Klinefelter syndrome: more than hypogonadism.
Kanakis GA, Nieschlag E. Kanakis GA, et al. Metabolism. 2018 Sep;86:135-144. doi: 10.1016/j.metabol.2017.09.017. Epub 2018 Jan 31. Metabolism. 2018. PMID: 29382506 Review.
Accordingly, hypogonadism is usually not evident until early adulthood and progresses with ageing. KS patients present a series of comorbidities that increase morbidity and mortality by 40%. Such disturbances are the impaired metabolic profile (obesity, dyslipidemia, insul …
Accordingly, hypogonadism is usually not evident until early adulthood and progresses with ageing. KS patients present a series of comorbidi …
Dental Problems in Primary Care.
Stephens MB, Wiedemer JP, Kushner GM. Stephens MB, et al. Am Fam Physician. 2018 Dec 1;98(11):654-660. Am Fam Physician. 2018. PMID: 30485039 Free article. Review.
Incision and drainage is the treatment of choice for dental abscess. Risk factors for periodontal disease include smoking, diabetes, human immunodeficiency virus infection, use of certain medications, and genetic susceptibility. ...Primary care clinicians are well p …
Incision and drainage is the treatment of choice for dental abscess. Risk factors for periodontal disease include smoking, diabetes, …
An atlas of genetic influences on osteoporosis in humans and mice.
Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, Simon MM, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum AT, Mannan NS, Komla-Ebri DSK, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar MG; 23andMe Research Team; Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani EE, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu YH, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB. Morris JA, et al. Nat Genet. 2019 Feb;51(2):258-266. doi: 10.1038/s41588-018-0302-x. Epub 2018 Dec 31. Nat Genet. 2019. PMID: 30598549 Free PMC article.
Osteoporosis is a common aging-related disease diagnosed primarily using bone mineral density (BMD). We assessed genetic determinants of BMD as estimated by heel quantitative ultrasound in 426,824 individuals, identifying 518 genome-wide significant loci (301 novel) …
Osteoporosis is a common aging-related disease diagnosed primarily using bone mineral density (BMD). We assessed genetic deter …
A road map for understanding molecular and genetic determinants of osteoporosis.
Yang TL, Shen H, Liu A, Dong SS, Zhang L, Deng FY, Zhao Q, Deng HW. Yang TL, et al. Nat Rev Endocrinol. 2020 Feb;16(2):91-103. doi: 10.1038/s41574-019-0282-7. Epub 2019 Dec 2. Nat Rev Endocrinol. 2020. PMID: 31792439 Free PMC article. Review.
Osteoporosis is a highly prevalent disorder characterized by low bone mineral density and an increased risk of fracture, termed osteoporotic fracture. Notably, bone mineral density, osteoporosis and osteoporotic fracture are highly herita …
Osteoporosis is a highly prevalent disorder characterized by low bone mineral density and an increased risk of fracture
Percutaneous vertebroplasty for osteoporotic vertebral compression fracture.
Buchbinder R, Johnston RV, Rischin KJ, Homik J, Jones CA, Golmohammadi K, Kallmes DF. Buchbinder R, et al. Cochrane Database Syst Rev. 2018 Apr 4;4(4):CD006349. doi: 10.1002/14651858.CD006349.pub3. Cochrane Database Syst Rev. 2018. Update in: Cochrane Database Syst Rev. 2018 Nov 06;11:CD006349. doi: 10.1002/14651858.CD006349.pub4. PMID: 29618171 Free PMC article. Updated. Review.
As it is least prone to bias, vertebroplasty compared with placebo was the primary comparison. Major outcomes were mean overall pain, disability, disease-specific and overall health-related quality of life, patient-reported treatment success, new symptomatic vertebral f
As it is least prone to bias, vertebroplasty compared with placebo was the primary comparison. Major outcomes were mean overall pain, disabi …
American Medical Society for Sports Medicine position statement: concussion in sport.
Harmon KG, Drezner JA, Gammons M, Guskiewicz KM, Halstead M, Herring SA, Kutcher JS, Pana A, Putukian M, Roberts WO. Harmon KG, et al. Br J Sports Med. 2013 Jan;47(1):15-26. doi: 10.1136/bjsports-2012-091941. Br J Sports Med. 2013. PMID: 23243113 Review.
SHORT-TERM RISKS OF PREMATURE RTP: The primary concern with early RTP is decreased reaction time leading to an increased risk of a repeat concussion or other injury and prolongation of symptoms. LONG-TERM EFFECTS: There is an increasing concern that head impact expo …
SHORT-TERM RISKS OF PREMATURE RTP: The primary concern with early RTP is decreased reaction time leading to an increased risk of a re …
Epigenetic regulation of bone mass.
Curtis EM, Fuggle NR, Cooper C, Harvey NC. Curtis EM, et al. Best Pract Res Clin Endocrinol Metab. 2022 Mar;36(2):101612. doi: 10.1016/j.beem.2021.101612. Epub 2022 Jan 4. Best Pract Res Clin Endocrinol Metab. 2022. PMID: 35120798 Free PMC article. Review.
Osteoporosis, characterised by low bone mass, poor bone structure, and an increased risk of fracture, is a major public health problem. There is increasing evidence that the influence of the environment on gene expression, through epigenetic pro …
Osteoporosis, characterised by low bone mass, poor bone structure, and an increased risk of fracture, is a major …
Paget's Disease of Bone.
Gennari L, Rendina D, Falchetti A, Merlotti D. Gennari L, et al. Calcif Tissue Int. 2019 May;104(5):483-500. doi: 10.1007/s00223-019-00522-3. Epub 2019 Jan 23. Calcif Tissue Int. 2019. PMID: 30671590 Review.
Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by increased osteoclast-mediated bone resorption and a subsequent compensatory increase in bone formation, resulting in a disorganized mosaic of wove …
Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by increased osteoclast-mediat …
279 results