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135 results

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Quoted phrase not found in phrase index: "Increased susceptibility to multiple carcinomas"
Page 1
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN, Christiani DC, Settleman J, Haber DA. Lynch TJ, et al. N Engl J Med. 2004 May 20;350(21):2129-39. doi: 10.1056/NEJMoa040938. Epub 2004 Apr 29. N Engl J Med. 2004. PMID: 15118073 Free article.
In vitro, EGFR mutants demonstrated enhanced tyrosine kinase activity in response to epidermal growth factor and increased sensitivity to inhibition by gefitinib. CONCLUSIONS: A subgroup of patients with non-small-cell lung cancer have specific mutations in the EGFR gene, …
In vitro, EGFR mutants demonstrated enhanced tyrosine kinase activity in response to epidermal growth factor and increased sensitivit …
Diagnosis and Treatment of Breast Cancer in Men.
Zehr KR. Zehr KR. Radiol Technol. 2019 Sep;91(1):51M-61M. Radiol Technol. 2019. PMID: 31471487 Review.
Breast cancer occurs in about 1% of men, but the number of men receiving a diagnosis is increasing. Data on male breast cancer (MBC) is limited, and treatment for men is based primarily on treatments used for women. However, some argue that breast cancer in men is a differ …
Breast cancer occurs in about 1% of men, but the number of men receiving a diagnosis is increasing. Data on male breast cancer (MBC) …
Insulin-Like Growth Factor 1 (IGF-1) Signaling in Glucose Metabolism in Colorectal Cancer.
Kasprzak A. Kasprzak A. Int J Mol Sci. 2021 Jun 16;22(12):6434. doi: 10.3390/ijms22126434. Int J Mol Sci. 2021. PMID: 34208601 Free PMC article. Review.
Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide, characterized by unfavorable curative effect and poor prognosis. Epidemiological data re-vealed that CRC risk is increased in patients with metabolic syndrome (MetS) and its seru …
Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide, characterized by unfavorable curative effect …
ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles.
Seo W, Gao Y, He Y, Sun J, Xu H, Feng D, Park SH, Cho YE, Guillot A, Ren T, Wu R, Wang J, Kim SJ, Hwang S, Liangpunsakul S, Yang Y, Niu J, Gao B. Seo W, et al. J Hepatol. 2019 Nov;71(5):1000-1011. doi: 10.1016/j.jhep.2019.06.018. Epub 2019 Jul 4. J Hepatol. 2019. PMID: 31279903 Free PMC article.
RESULTS: We demonstrated that ALDH2 deficiency was not associated with liver disease progression but was associated with an increased risk of HCC development in cirrhotic patients with HBV who consumed excessive alcohol. ...Mechanistic studies reveal a novel mechani …
RESULTS: We demonstrated that ALDH2 deficiency was not associated with liver disease progression but was associated with an increa …
Acute kidney injury in cancer patients.
César BN, Durão Júnior MS. César BN, et al. Rev Assoc Med Bras (1992). 2020 Jan 13;66Suppl 1(Suppl 1):s25-s30. doi: 10.1590/1806-9282.66.S1.25. Rev Assoc Med Bras (1992). 2020. PMID: 31939532 Free article. Review.
The increasing prevalence of neoplasias is associated with new clinical challenges, one of which is acute kidney injury (AKI). ...Some types of neoplasia are more susceptible to AKI, such as multiple myeloma and renal carcinoma. In cancer patien …
The increasing prevalence of neoplasias is associated with new clinical challenges, one of which is acute kidney injury (AKI). …
Cutaneous squamous cell carcinoma: an epidemiological review.
Green AC, Olsen CM. Green AC, et al. Br J Dermatol. 2017 Aug;177(2):373-381. doi: 10.1111/bjd.15324. Epub 2017 Feb 16. Br J Dermatol. 2017. PMID: 28211039 Review.
Cutaneous squamous cell carcinoma (SCC) is a common cancer in white populations and its disease burden is often substantially underestimated. SCC occurs more often in men than women and increases dramatically with age; those affected often develop multiple …
Cutaneous squamous cell carcinoma (SCC) is a common cancer in white populations and its disease burden is often substantially …
The Role of Respiratory Microbiota in Lung Cancer.
Wang D, Cheng J, Zhang J, Zhou F, He X, Shi Y, Tao Y. Wang D, et al. Int J Biol Sci. 2021 Aug 25;17(13):3646-3658. doi: 10.7150/ijbs.51376. eCollection 2021. Int J Biol Sci. 2021. PMID: 34512172 Free PMC article. Review.
The microbiota may increase tumor susceptibility by altering metabolism and immune responses, promoting inflammation, and increasing toxic effects. The microbiota can regulate tumor metastasis by altering multiple cell signaling pathways and participat …
The microbiota may increase tumor susceptibility by altering metabolism and immune responses, promoting inflammation, and i …
Mechanisms of PARP inhibitor resistance in ovarian cancer.
Kubalanza K, Konecny GE. Kubalanza K, et al. Curr Opin Obstet Gynecol. 2020 Feb;32(1):36-41. doi: 10.1097/GCO.0000000000000600. Curr Opin Obstet Gynecol. 2020. PMID: 31815769 Review.
However, only few of these mechanisms have been identified in clinical samples. SUMMARY: Multiple adaptive responses following PARP inhibitor treatment have been identified. Further research is needed to better understand what role these mechanisms play for clini …
However, only few of these mechanisms have been identified in clinical samples. SUMMARY: Multiple adaptive responses following …
The complex spectrum of forensic issues arising from obesity.
Byard RW. Byard RW. Forensic Sci Med Pathol. 2012 Dec;8(4):402-13. doi: 10.1007/s12024-012-9322-5. Epub 2012 Mar 1. Forensic Sci Med Pathol. 2012. PMID: 22383171 Review.
Accelerated putrefaction is often an added complication. Metabolic disturbances resulting from obesity increase susceptibility to a range of conditions that are associated with sudden and unexpected death, and surgery may have increased complications. The rat …
Accelerated putrefaction is often an added complication. Metabolic disturbances resulting from obesity increase susceptibility …
Familial pancreatic cancer: Concept, management and issues.
Matsubayashi H, Takaori K, Morizane C, Maguchi H, Mizuma M, Takahashi H, Wada K, Hosoi H, Yachida S, Suzuki M, Usui R, Furukawa T, Furuse J, Sato T, Ueno M, Kiyozumi Y, Hijioka S, Mizuno N, Terashima T, Mizumoto M, Kodama Y, Torishima M, Kawaguchi T, Ashida R, Kitano M, Hanada K, Furukawa M, Kawabe K, Majima Y, Shimosegawa T. Matsubayashi H, et al. World J Gastroenterol. 2017 Feb 14;23(6):935-948. doi: 10.3748/wjg.v23.i6.935. World J Gastroenterol. 2017. PMID: 28246467 Free PMC article. Review.
Several genetic syndromes, including Peutz-Jeghers syndrome, hereditary pancreatitis, hereditary breast-ovarian cancer syndrome (HBOC), Lynch syndrome, and familial adenomatous polyposis (FAP), also have increased risks of PC, but the narrowest definition of FPC excludes t …
Several genetic syndromes, including Peutz-Jeghers syndrome, hereditary pancreatitis, hereditary breast-ovarian cancer syndrome (HBOC), Lync …
135 results