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Quoted phrase not found in phrase index: "Infant Acute Biphenotypic Leukemia"
Page 1
A systematic description of MLL fusion gene formation.
Wright RL, Vaughan AT. Wright RL, et al. Crit Rev Oncol Hematol. 2014 Sep;91(3):283-91. doi: 10.1016/j.critrevonc.2014.03.004. Epub 2014 Apr 8. Crit Rev Oncol Hematol. 2014. PMID: 24787275 Review.
Rearrangements of the MLL gene involve multiple partners and are implicated in both therapy related acute leukemia [tAL] and infant acute leukemia. For these diseases, recently compiled clinical data confirms an elevated frequency of such …
Rearrangements of the MLL gene involve multiple partners and are implicated in both therapy related acute leukemia [tAL] and …
Clinical characteristics and outcome of children with biphenotypic acute leukemia.
Al-Seraihy AS, Owaidah TM, Ayas M, El-Solh H, Al-Mahr M, Al-Ahmari A, Belgaumi AF. Al-Seraihy AS, et al. Haematologica. 2009 Dec;94(12):1682-90. doi: 10.3324/haematol.2009.009282. Epub 2009 Aug 27. Haematologica. 2009. PMID: 19713227 Free PMC article.
BACKGROUND: Knowledge concerning the clinical and biological presentation, as well as the outcome of treatment, of biphenotypic acute leukemia in children is limited. ...According to the EGIL scoring system 24 (3.7%) of 633 patients with acute …
BACKGROUND: Knowledge concerning the clinical and biological presentation, as well as the outcome of treatment, of biphenotypic …
Diagnosis and management of neonatal leukaemia.
van der Linden MH, Creemers S, Pieters R. van der Linden MH, et al. Semin Fetal Neonatal Med. 2012 Aug;17(4):192-195. doi: 10.1016/j.siny.2012.03.003. Epub 2012 Apr 15. Semin Fetal Neonatal Med. 2012. PMID: 22510298 Review.
Leukaemia in neonates (infants <1 month) is rare, whereby neonatal acute myeloid leukaemia (AML) is more frequent than neonatal acute lymphoblastic leukaemia (ALL). ...
Leukaemia in neonates (infants <1 month) is rare, whereby neonatal acute myeloid leukaemia (AML) is more frequent than neon …
Chromosomal translocations involving the MLL gene: molecular mechanisms.
Aplan PD. Aplan PD. DNA Repair (Amst). 2006 Sep 8;5(9-10):1265-72. doi: 10.1016/j.dnarep.2006.05.034. Epub 2006 Jun 21. DNA Repair (Amst). 2006. PMID: 16797254 Free PMC article. Review.
A wide array of recurrent, non-random chromosomal translocations are associated with hematologic malignancies; experimental models have clearly demonstrated that many of these translocations are causal events during malignant transformation. Translocations involving the ML …
A wide array of recurrent, non-random chromosomal translocations are associated with hematologic malignancies; experimental models ha …
Acute leukaemias of ambiguous lineage in children: characterization, prognosis and therapy recommendations.
Gerr H, Zimmermann M, Schrappe M, Dworzak M, Ludwig WD, Bradtke J, Moericke A, Schabath R, Creutzig U, Reinhardt D. Gerr H, et al. Br J Haematol. 2010 Apr;149(1):84-92. doi: 10.1111/j.1365-2141.2009.08058.x. Epub 2010 Jan 18. Br J Haematol. 2010. PMID: 20085575 Free article.
Acute leukaemias of ambiguous lineage (ALAL) represent a rare type of leukaemia, expressing both myeloid and lymphoid markers. This study retrospectively analyzed data from 92 children (biphenotypic n = 78, bilineal n = 6, lineage switch n = 8) with ALAL registered …
Acute leukaemias of ambiguous lineage (ALAL) represent a rare type of leukaemia, expressing both myeloid and lymphoid markers. This s …
Mixed-phenotype acute leukemia: A cohort and consensus research strategy from the Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task Force.
Orgel E, Alexander TB, Wood BL, Kahwash SB, Devidas M, Dai Y, Alonzo TA, Mullighan CG, Inaba H, Hunger SP, Raetz EA, Gamis AS, Rabin KR, Carroll AJ 3rd, Heerema NA, Berman JN, Woods WG, Loh ML, Zweidler-McKay PA, Horan JT; Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task Force. Orgel E, et al. Cancer. 2020 Feb 1;126(3):593-601. doi: 10.1002/cncr.32552. Epub 2019 Oct 29. Cancer. 2020. PMID: 31661160 Free PMC article.
BACKGROUND: Optimal chemotherapy for treating mixed-phenotype acute leukemia (MPAL) and the role of hematopoietic stem cell transplantation (HSCT) remain uncertain. ...METHODS: To assess the relative efficacy of chemotherapy types for treating pediatric MPAL, the Ch …
BACKGROUND: Optimal chemotherapy for treating mixed-phenotype acute leukemia (MPAL) and the role of hematopoietic stem cell tr …
Acute lymphoblastic leukemia-like treatment regimen provides better response in mixed phenotype acute leukemia: a comparative study between adults and pediatric MPAL patients.
Rasekh EO, Osman R, Ibraheem D, Madney Y, Radwan E, Gameel A, Abdelhafiz A, Kamel A, Elfishawi S. Rasekh EO, et al. Ann Hematol. 2021 Mar;100(3):699-707. doi: 10.1007/s00277-020-04354-2. Epub 2020 Nov 23. Ann Hematol. 2021. PMID: 33230570
Mixed phenotype acute leukemia (MPAL) is a rare type of leukemia with a limited number of studies conducted to characterize its clinical spectrum and most importantly the best treatment modality. ...The incidence of MPAL was 4% of acute leuke …
Mixed phenotype acute leukemia (MPAL) is a rare type of leukemia with a limited number of studies conducted to characte …
Pregnancy, maternal exposure to hair dyes and hair straightening cosmetics, and early age leukemia.
Couto AC, Ferreira JD, Rosa AC, Pombo-de-Oliveira MS, Koifman S; Brazilian Collaborative Study Group of Infant Acute Leukemia. Couto AC, et al. Chem Biol Interact. 2013 Sep 5;205(1):46-52. doi: 10.1016/j.cbi.2013.05.012. Epub 2013 Jun 6. Chem Biol Interact. 2013. PMID: 23747844 Free article.
Mothers of 176 ALL (acute lymphocytic leukemia) and 55 AML (acute myeloid leukemia) cases and 419 controls were enrolled and interviewed. ...No association between maternal exposure to HDSC during pregnancy and ALL or AML was observed in children with …
Mothers of 176 ALL (acute lymphocytic leukemia) and 55 AML (acute myeloid leukemia) cases and 419 controls were …
Controversies of and unique issues in hematopoietic cell transplantation for infant leukemia.
Hunger SP, Loh KM, Baker KS, Schultz KR. Hunger SP, et al. Biol Blood Marrow Transplant. 2009 Jan;15(1 Suppl):79-83. doi: 10.1016/j.bbmt.2008.10.015. Biol Blood Marrow Transplant. 2009. PMID: 19147083 Free article.
Infant leukemia is characterized by a unique biology including a predominance mixed lineage leukemia(MLL) gene rearrangement and juvenile myelomonocytic leukemia. ...Currently, there is no solid basis to support allogeneic HCT as first-line therapy for …
Infant leukemia is characterized by a unique biology including a predominance mixed lineage leukemia(MLL) gene rearrang …
Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia.
Richmond J, Carol H, Evans K, High L, Mendomo A, Robbins A, Meyer C, Venn NC, Marschalek R, Henderson M, Sutton R, Kurmasheva RT, Kees UR, Houghton PJ, Smith MA, Lock RB. Richmond J, et al. Clin Cancer Res. 2015 Mar 15;21(6):1395-405. doi: 10.1158/1078-0432.CCR-14-2300. Epub 2015 Jan 8. Clin Cancer Res. 2015. PMID: 25573381 Free PMC article.
PURPOSE: Although the overall cure rate for pediatric acute lymphoblastic leukemia (ALL) approaches 90%, infants with ALL harboring translocations in the mixed-lineage leukemia (MLL) oncogene (infant MLL-ALL) experience shorter remission duratio …
PURPOSE: Although the overall cure rate for pediatric acute lymphoblastic leukemia (ALL) approaches 90%, infants with A …
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