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Quoted phrase not found in phrase index: "Inosine phosphorylase deficiency, immune defect due to"
Page 1
Cellular immune deficiency with autoimmune hemolytic anemia in purine nucleoside phosphorylase deficiency.
Rich KC, Arnold WJ, Palella T, Fox IH. Rich KC, et al. Am J Med. 1979 Jul;67(1):172-6. doi: 10.1016/0002-9343(79)90100-1. Am J Med. 1979. PMID: 111549
Immunologic and metabolic abnormalities were studied in a five year old boy with 0.07 per cent of normal erythrocyte purine nucleoside phosphorylase activity. ...In addition, the unusual laboratory and clinical manifestations of this patient illustrate …
Immunologic and metabolic abnormalities were studied in a five year old boy with 0.07 per cent of normal erythrocyte purine …
Decreased adenosine deaminase (ADA) and 5'nucleotidase (5NT) activity in peripheral blood T cells in Hodgkin disease.
Murray JL, Perez-Soler R, Bywaters D, Hersh EM. Murray JL, et al. Am J Hematol. 1986 Jan;21(1):57-66. doi: 10.1002/ajh.2830210108. Am J Hematol. 1986. PMID: 3010705
The purine metabolic enzymes adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), and 5'nucleotidase (5NT) play an important role in normal lymphocyte differentiation. ...Low 5NT activity was present irrespective of whether patients had active di …
The purine metabolic enzymes adenosine deaminase (ADA), purine nucleoside phosphorylase (PNP), and 5'nucleotidase (5NT) …
Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation.
Buckley RH, Schiff SE, Sampson HA, Schiff RI, Markert ML, Knutsen AP, Hershfield MS, Huang AT, Mickey GH, Ward FE. Buckley RH, et al. J Immunol. 1986 Apr 1;136(7):2398-407. J Immunol. 1986. PMID: 2869085
Recent advances in the prevention of graft-vs-host disease (GVHD) have allowed the use of haploidentical bone marrow cells for correction of lethal genetic defects of the immune system. Sequential analyses of blood lymphocyte phenotypes and functions were done befor …
Recent advances in the prevention of graft-vs-host disease (GVHD) have allowed the use of haploidentical bone marrow cells for correction of …
Purine nucleoside phosphorylase deficiency: a new case report and identification of two novel mutations (Gly156A1a and Val217Ile), only one of which (Gly156A1a) is deleterious.
Moallem HJ, Taningo G, Jiang CK, Hirschhorn R, Fikrig S. Moallem HJ, et al. Clin Immunol. 2002 Oct;105(1):75-80. doi: 10.1006/clim.2002.5264. Clin Immunol. 2002. PMID: 12483996
Purine nucleoside phosphorylase (PNP) deficiency results in an autosomal recessive immunodeficiency disease characterized by initial involvement of cellular immunity and neurological manifestations with subsequent abnormalities of humoral …
Purine nucleoside phosphorylase (PNP) deficiency results in an autosomal recessive immunodeficiency disease char …
Deoxyadenosine triphosphate as a mediator of deoxyguanosine toxicity in cultured T lymphoblasts.
Mann GJ, Fox RM. Mann GJ, et al. J Clin Invest. 1986 Nov;78(5):1261-9. doi: 10.1172/JCI112710. J Clin Invest. 1986. PMID: 3490493 Free PMC article.
The mechanism by which 2'-deoxyguanosine is toxic for lymphoid cells is relevant both to the severe cellular immune defect of inherited purine nucleoside phosphorylase (PNP) deficiency and to attempts to exploit PNP inhibitors therapeutic …
The mechanism by which 2'-deoxyguanosine is toxic for lymphoid cells is relevant both to the severe cellular immune defect of …