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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1978 1
1986 1
1989 1
1991 1
1993 4
1994 1
1995 1
1996 3
1997 5
1998 3
1999 6
2000 8
2001 3
2002 4
2003 13
2004 11
2005 16
2006 12
2007 13
2008 18
2009 21
2010 31
2011 33
2012 32
2013 37
2014 38
2015 35
2016 34
2017 28
2018 26
2019 23
2020 26
2021 25
2022 13
2023 10
2024 3

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448 results

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Page 1
Genetics.
Domschke K, Deckert J. Domschke K, et al. Curr Top Behav Neurosci. 2010;2:63-75. Curr Top Behav Neurosci. 2010. PMID: 21309106 Review.
Furthermore, the first imaging genetic findings in panic disorder, social phobia, and anxiety-related traits using fMRI and PET techniques in combination with molecular genetic association analyses are reviewed, taking into account the present intermediate phenotype …
Furthermore, the first imaging genetic findings in panic disorder, social phobia, and anxiety-related traits using fMRI and PET techniques i …
Advances in integrative African genomics.
Zhang C, Hansen MEB, Tishkoff SA. Zhang C, et al. Trends Genet. 2022 Feb;38(2):152-168. doi: 10.1016/j.tig.2021.09.013. Epub 2021 Nov 2. Trends Genet. 2022. PMID: 34740451 Free PMC article. Review.
Impaired inhibition as an intermediate phenotype for PTSD risk and treatment response.
van Rooij SJH, Jovanovic T. van Rooij SJH, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:435-445. doi: 10.1016/j.pnpbp.2018.10.014. Epub 2018 Oct 28. Prog Neuropsychopharmacol Biol Psychiatry. 2019. PMID: 30381236 Free PMC article. Review.
Response inhibition refers to cognitive control and likely uses the same prefrontal cortex circuits as fear inhibition, and has also been implicated in PTSD. Impaired inhibition can serve as an intermediate phenotype for PTSD and can be measured with neuroimaging an …
Response inhibition refers to cognitive control and likely uses the same prefrontal cortex circuits as fear inhibition, and has also been im …
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
Broadaway KA, Yin X, Williamson A, Parsons VA, Wilson EP, Moxley AH, Vadlamudi S, Varshney A, Jackson AU, Ahuja V, Bornstein SR, Corbin LJ, Delgado GE, Dwivedi OP, Fernandes Silva L, Frayling TM, Grallert H, Gustafsson S, Hakaste L, Hammar U, Herder C, Herrmann S, Højlund K, Hughes DA, Kleber ME, Lindgren CM, Liu CT, Luan J, Malmberg A, Moissl AP, Morris AP, Perakakis N, Peters A, Petrie JR, Roden M, Schwarz PEH, Sharma S, Silveira A, Strawbridge RJ, Tuomi T, Wood AR, Wu P, Zethelius B, Baldassarre D, Eriksson JG, Fall T, Florez JC, Fritsche A, Gigante B, Hamsten A, Kajantie E, Laakso M, Lahti J, Lawlor DA, Lind L, März W, Meigs JB, Sundström J, Timpson NJ, Wagner R, Walker M, Wareham NJ, Watkins H, Barroso I, O'Rahilly S, Grarup N, Parker SC, Boehnke M, Langenberg C, Wheeler E, Mohlke KL. Broadaway KA, et al. Am J Hum Genet. 2023 Feb 2;110(2):284-299. doi: 10.1016/j.ajhg.2023.01.002. Epub 2023 Jan 23. Am J Hum Genet. 2023. PMID: 36693378 Free PMC article.
Signals were enriched for islet enhancers, and we showed a plausible islet regulatory mechanism for the lead signal in the MADD locus. These results show how detailed genetic studies of an intermediate phenotype can elucidate mechanisms that may predispose one to di …
Signals were enriched for islet enhancers, and we showed a plausible islet regulatory mechanism for the lead signal in the MADD locus. These …
Challenges and Approach to Identifying Individuals with Salt Sensitivity of Blood Pressure.
Parksook WW, Williams GH. Parksook WW, et al. Am J Nephrol. 2022;53(11-12):847-855. doi: 10.1159/000529057. Epub 2023 Jan 11. Am J Nephrol. 2022. PMID: 36630945 Free article. Review.
BACKGROUND: Salt sensitivity of blood pressure (SSBP) is a trait observed in both humans and animals, characterized by an increase in blood pressure (BP) following salt loading or a drop in BP following salt depletion. SUMMARY: This "intermediate" phenotype has been …
BACKGROUND: Salt sensitivity of blood pressure (SSBP) is a trait observed in both humans and animals, characterized by an increase in blood …
The paradigm of immunosenescence in atherosclerosis-cardiovascular disease (ASCVD).
Laderoute M. Laderoute M. Discov Med. 2020 Jan-Feb;29(156):41-51. Discov Med. 2020. PMID: 32598862 Free article. Review.
Moreover, the monocyte/macrophage phenotype implicated in atherosclerosis-cardiovascular disease (ASCVD) appears to be the CD14+CD16+ intermediate phenotype. These and other observations directly challenge the cholesterol hypothesis. ...
Moreover, the monocyte/macrophage phenotype implicated in atherosclerosis-cardiovascular disease (ASCVD) appears to be the CD14+CD16+ int …
Personality as an intermediate phenotype for genetic dissection of alcohol use disorder.
Oreland L, Lagravinese G, Toffoletto S, Nilsson KW, Harro J, Robert Cloninger C, Comasco E. Oreland L, et al. J Neural Transm (Vienna). 2018 Jan;125(1):107-130. doi: 10.1007/s00702-016-1672-9. Epub 2017 Jan 4. J Neural Transm (Vienna). 2018. PMID: 28054193 Free PMC article. Review.
Intermediate phenotypes are expected to be in-between proxies of basic neuronal biological processes and nosological symptoms of AUD. Personality is likely to be a top candidate intermediate phenotype for the dissection of the genetic underpinnings of different subt …
Intermediate phenotypes are expected to be in-between proxies of basic neuronal biological processes and nosological symptoms of AUD. Person …
448 results