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Quoted phrase not found in phrase index: "Iron accumulation in brain"
Page 1
Neurodegeneration with brain iron accumulation.
Hayflick SJ, Kurian MA, Hogarth P. Hayflick SJ, et al. Handb Clin Neurol. 2018;147:293-305. doi: 10.1016/B978-0-444-63233-3.00019-1. Handb Clin Neurol. 2018. PMID: 29325618 Free PMC article. Review.
Neurodegeneration with brain iron accumulation (NBIA) comprises a clinically and genetically heterogeneous group of disorders affecting children and adults. These rare disorders are often first suspected when increased basal ganglia iron is observed on …
Neurodegeneration with brain iron accumulation (NBIA) comprises a clinically and genetically heterogeneous group of dis …
Cerebral Iron Deposition in Neurodegeneration.
Dusek P, Hofer T, Alexander J, Roos PM, Aaseth JO. Dusek P, et al. Biomolecules. 2022 May 17;12(5):714. doi: 10.3390/biom12050714. Biomolecules. 2022. PMID: 35625641 Free PMC article. Review.
We also provide an update on mechanisms, biomarkers, and effects of brain iron accumulation in these disorders, focusing on recent publications. ...On the microscopic level, brain iron deposits are present mostly in dystrophic microglia variably …
We also provide an update on mechanisms, biomarkers, and effects of brain iron accumulation in these disorders, focusin …
Vitamin C, Aging and Alzheimer's Disease.
Monacelli F, Acquarone E, Giannotti C, Borghi R, Nencioni A. Monacelli F, et al. Nutrients. 2017 Jun 27;9(7):670. doi: 10.3390/nu9070670. Nutrients. 2017. PMID: 28654021 Free PMC article. Review.
Accumulating evidence in mice models of accelerated senescence indicates a rescuing role of ascorbic acid in premature aging. ...The neuroprotective role of ascorbic acid not only relies on the general free radical trapping, but also on the suppression of pro-inflammatory …
Accumulating evidence in mice models of accelerated senescence indicates a rescuing role of ascorbic acid in premature aging. ...The …
Molecular Physiology and Pathophysiology of Bilirubin Handling by the Blood, Liver, Intestine, and Brain in the Newborn.
Hansen TWR, Wong RJ, Stevenson DK. Hansen TWR, et al. Physiol Rev. 2020 Jul 1;100(3):1291-1346. doi: 10.1152/physrev.00004.2019. Physiol Rev. 2020. PMID: 32401177 Free article. Review.
Bilirubin is the end product of heme catabolism formed during a process that involves oxidation-reduction reactions and conserves iron body stores. Unconjugated hyperbilirubinemia is common in newborn infants, but rare later in life. ...Here we review the chemistry of the …
Bilirubin is the end product of heme catabolism formed during a process that involves oxidation-reduction reactions and conserves iron …
PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron.
Morgan NV, Westaway SK, Morton JE, Gregory A, Gissen P, Sonek S, Cangul H, Coryell J, Canham N, Nardocci N, Zorzi G, Pasha S, Rodriguez D, Desguerre I, Mubaidin A, Bertini E, Trembath RC, Simonati A, Schanen C, Johnson CA, Levinson B, Woods CG, Wilmot B, Kramer P, Gitschier J, Maher ER, Hayflick SJ. Morgan NV, et al. Nat Genet. 2006 Jul;38(7):752-4. doi: 10.1038/ng1826. Epub 2006 Jun 18. Nat Genet. 2006. PMID: 16783378 Free PMC article.
Neurodegenerative disorders with high brain iron include Parkinson disease, Alzheimer disease and several childhood genetic disorders categorized as neuroaxonal dystrophies. We mapped a locus for infantile neuroaxonal dystrophy (INAD) and neurodegeneration with b …
Neurodegenerative disorders with high brain iron include Parkinson disease, Alzheimer disease and several childhood genetic di …
Axonal dystrophies.
Nardocci N, Zorzi G. Nardocci N, et al. Handb Clin Neurol. 2013;113:1919-24. doi: 10.1016/B978-0-444-59565-2.00062-9. Handb Clin Neurol. 2013. PMID: 23622415 Review.
These disorders show the unique pathological feature of neuroaxonal dystrophy (NAD): axonal swelling (spheroids) localized throughout the central nervous and peripheral nervous systems. NADs are also morphologically characterized by iron accumulation in the basal ga …
These disorders show the unique pathological feature of neuroaxonal dystrophy (NAD): axonal swelling (spheroids) localized throughout the ce …
Neurodegeneration with brain iron accumulation.
Wiethoff S, Houlden H. Wiethoff S, et al. Handb Clin Neurol. 2017;145:157-166. doi: 10.1016/B978-0-12-802395-2.00011-0. Handb Clin Neurol. 2017. PMID: 28987166 Review.
Neurodegeneration with brain iron accumulation (NBIA) describes a heterogeneous group of inherited rare clinical and genetic entities. ...Neuropathologically, NBIA disorders usually are associated with widespread axonal spheroids and local iron accu …
Neurodegeneration with brain iron accumulation (NBIA) describes a heterogeneous group of inherited rare clinical and ge …
Neurodegeneration with Brain Iron Accumulation.
Schneider SA. Schneider SA. Curr Neurol Neurosci Rep. 2016 Jan;16(1):9. doi: 10.1007/s11910-015-0608-3. Curr Neurol Neurosci Rep. 2016. PMID: 26739693 Review.
Syndromes with neurodegeneration with brain iron accumulation (NBIA) are a group of neurodegenerative disorders characterized by abnormalities in brain iron metabolism with excess iron accumulation in the globus pallidus and to a l …
Syndromes with neurodegeneration with brain iron accumulation (NBIA) are a group of neurodegenerative disorders charact …
Neurodegenerations with Brain Iron Accumulation.
Schneider SA. Schneider SA. Parkinsonism Relat Disord. 2016 Jan;22 Suppl 1:S21-5. doi: 10.1016/j.parkreldis.2015.08.012. Epub 2015 Aug 14. Parkinsonism Relat Disord. 2016. PMID: 26320888 Review.
Syndromes with Neurodegeneration with Brain Iron Accumulation (NBIA) are a group of neurodegenerative disorders characterized by excess iron mainly in the globus pallidus and sometimes adjacent areas. ...
Syndromes with Neurodegeneration with Brain Iron Accumulation (NBIA) are a group of neurodegenerative disorders charact …
Identifying Genetic Risk for Amyloid-Related Imaging Abnormalities.
Hardy J, Schott JM. Hardy J, et al. Neurology. 2024 Feb 13;102(3):e208096. doi: 10.1212/WNL.0000000000208096. Epub 2023 Dec 28. Neurology. 2024. PMID: 38165303
In the last 2 years, there have been 3 successful trials of antiamyloid antibodies in Alzheimer disease (AD): aducanemab, now controversially US Food and Drug Administration-approved under the accelerated approval pathway(1); lecanemab, now FDA-approved(2); and donanemab, now goi …
In the last 2 years, there have been 3 successful trials of antiamyloid antibodies in Alzheimer disease (AD): aducanemab, now controversiall …
596 results