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1965 1
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2007 3
2008 1
2009 1
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2014 4
2015 5
2016 1
2017 4
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52 results

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Page 1
The immunopathogenesis of narcolepsy type 1.
Liblau RS, Latorre D, Kornum BR, Dauvilliers Y, Mignot EJ. Liblau RS, et al. Nat Rev Immunol. 2024 Jan;24(1):33-48. doi: 10.1038/s41577-023-00902-9. Epub 2023 Jul 3. Nat Rev Immunol. 2024. PMID: 37400646 Review.
An immune-mediated pathology for NT1 has long been suspected given its exceptionally tight association with the MHC class II allele HLA-DQB1*06:02, as well as recent genetic evidence showing associations with polymorphisms of T cell receptor genes and other immune-relevant loci a …
An immune-mediated pathology for NT1 has long been suspected given its exceptionally tight association with the MHC class II allele HLA-DQB1 …
Kleine-Levin syndrome; An update and mini-review.
Gadoth N, Oksenberg A. Gadoth N, et al. Brain Dev. 2017 Sep;39(8):665-671. doi: 10.1016/j.braindev.2017.04.003. Epub 2017 Apr 20. Brain Dev. 2017. PMID: 28434769 Review.
Since 1962, when Critchley and Hoffman coined the term Kleine-Levin Syndrome (KLS) for the triad of hypersomnia, excessive eating and "often abnormal behavior" which they have observed in 11 adolescent boys, the number of patients recognized with this …
Since 1962, when Critchley and Hoffman coined the term Kleine-Levin Syndrome (KLS) for the triad of hypersomnia, excess …
Sleep-Wake Disorders in Childhood.
Licis A. Licis A. Continuum (Minneap Minn). 2020 Aug;26(4):1034-1069. doi: 10.1212/CON.0000000000000897. Continuum (Minneap Minn). 2020. PMID: 32756235 Review.
Restless sleep disorder is a recently proposed entity in which restless sleep, daytime sleepiness, and often iron deficiency are observed, but children do not meet the criteria for restless legs syndrome or periodic limb movement disorder. ...Sleep disorders of childhood a …
Restless sleep disorder is a recently proposed entity in which restless sleep, daytime sleepiness, and often iron deficiency are observed …
Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.
Maski K, Trotti LM, Kotagal S, Robert Auger R, Swick TJ, Rowley JA, Hashmi SD, Watson NF. Maski K, et al. J Clin Sleep Med. 2021 Sep 1;17(9):1895-1945. doi: 10.5664/jcsm.9326. J Clin Sleep Med. 2021. PMID: 34743790 Free PMC article.
METHODS: The American Academy of Sleep Medicine commissioned a task force of experts in sleep medicine to perform a systematic review. Randomized controlled trials and observational studies addressing pharmacological and nonpharmacological interventions for central disorde …
METHODS: The American Academy of Sleep Medicine commissioned a task force of experts in sleep medicine to perform a systematic review. Rando …
Safety and efficacy of pitolisant in children aged 6 years or older with narcolepsy with or without cataplexy: a double-blind, randomised, placebo-controlled trial.
Dauvilliers Y, Lecendreux M, Lammers GJ, Franco P, Poluektov M, Caussé C, Lecomte I, Lecomte JM, Lehert P, Schwartz JC, Plazzi G. Dauvilliers Y, et al. Lancet Neurol. 2023 Apr;22(4):303-311. doi: 10.1016/S1474-4422(23)00036-4. Lancet Neurol. 2023. PMID: 36931805 Clinical Trial.
Participants were required to have a Pediatric Daytime Sleepiness Scale score of 15 or greater and to have not received psychostimulants for at least 14 days before enrolment; participants who needed anticataplectics (including sodium oxybate) were required to have been on …
Participants were required to have a Pediatric Daytime Sleepiness Scale score of 15 or greater and to have not received psychostimula …
Kleine-Levin syndrome is associated with birth difficulties and genetic variants in the TRANK1 gene loci.
Ambati A, Hillary R, Leu-Semenescu S, Ollila HM, Lin L, During EH, Farber N, Rico TJ, Faraco J, Leary E, Goldstein-Piekarski AN, Huang YS, Han F, Sivan Y, Lecendreux M, Dodet P, Honda M, Gadoth N, Nevsimalova S, Pizza F, Kanbayashi T, Peraita-Adrados R, Leschziner GD, Hasan R, Canellas F, Kume K, Daniilidou M, Bourgin P, Rye D, Vicario JL, Hogl B, Hong SC, Plazzi G, Mayer G, Landtblom AM, Dauvilliers Y, Arnulf I, Mignot EJ. Ambati A, et al. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2005753118. doi: 10.1073/pnas.2005753118. Proc Natl Acad Sci U S A. 2021. PMID: 33737391 Free PMC article.
Kleine-Levin syndrome (KLS) is a rare disorder characterized by severe episodic hypersomnia, with cognitive impairment accompanied by apathy or disinhibition. ...While the rs71947865 association did not replicate in the entire follow-up sample of 171 KLS case …
Kleine-Levin syndrome (KLS) is a rare disorder characterized by severe episodic hypersomnia, with cognitive impairment …
Kleine-Levin syndrome: a case report and review of literature.
Das S, Gupta R, Dhyani M, Raghuvanshi S. Das S, et al. Pediatr Neurol. 2014 Apr;50(4):411-6. doi: 10.1016/j.pediatrneurol.2014.01.003. Epub 2014 Jan 6. Pediatr Neurol. 2014. PMID: 24630285 Review.
BACKGROUND: Kleine-Levin syndrome presents with recurrent hypersomnia along with a number of other neuropsychiatric features, of which hyperorality has not been described frequently. ...The symptoms improved within a week after starting lithium carbonate ther …
BACKGROUND: Kleine-Levin syndrome presents with recurrent hypersomnia along with a number of other neuropsychiatric fea …
Serum cytokine levels in Kleine-Levin syndrome.
Kornum BR, Rico T, Lin L, Huang YS, Arnulf I, Jennum P, Mignot E. Kornum BR, et al. Sleep Med. 2015 Aug;16(8):961-5. doi: 10.1016/j.sleep.2015.02.540. Epub 2015 May 15. Sleep Med. 2015. PMID: 26116465
OBJECTIVE: Kleine-Levin Syndrome (KLS) is a rare sleep disorder causing recurrent symptomatic episodes of severe hypersomnia, cognitive impairment, apathy, and derealization. ...Processing of the samples was performed at the Stanford Center for Sleep Sciences …
OBJECTIVE: Kleine-Levin Syndrome (KLS) is a rare sleep disorder causing recurrent symptomatic episodes of severe hypers …
Different circadian rest-active rhythms in Kleine-Levin syndrome: a prospective and case-control study.
Lin C, Chin WC, Huang YS, Chu KC, Paiva T, Chen CC, Guilleminault C. Lin C, et al. Sleep. 2021 Sep 13;44(9):zsab096. doi: 10.1093/sleep/zsab096. Sleep. 2021. PMID: 33851710
STUDY OBJECTIVES: Kleine-Levin syndrome (KLS) is a rare recurrent hypersomnia. Our study aimed at monitoring the movements of patients with KLS using actigraphy and evaluating their circadian rhythm. ...Several parameters including M10, IS, and alpha1 may be …
STUDY OBJECTIVES: Kleine-Levin syndrome (KLS) is a rare recurrent hypersomnia. Our study aimed at monitoring the moveme …
Long-Term Cognitive Impairment in Kleine-Levin Syndrome.
Uguccioni G, Lavault S, Chaumereuil C, Golmard JL, Gagnon JF, Arnulf I. Uguccioni G, et al. Sleep. 2016 Feb 1;39(2):429-38. doi: 10.5665/sleep.5458. Sleep. 2016. PMID: 26414895 Free PMC article.
STUDY OBJECTIVES: In Kleine-Levin syndrome (KLS), episodes of hypersomnia, cognitive, and behavioral disturbances alternate with asymptomatic periods. ...Higher episode frequency, shorter episode duration, shorter time since last episode, deeper sleep, and me …
STUDY OBJECTIVES: In Kleine-Levin syndrome (KLS), episodes of hypersomnia, cognitive, and behavioral disturbances alter …
52 results