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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 5
1967 2
1968 4
1969 3
1970 7
1971 6
1972 12
1973 9
1974 8
1975 22
1976 18
1977 18
1978 20
1979 18
1980 12
1981 13
1982 12
1983 15
1984 15
1985 12
1986 21
1987 20
1988 10
1989 21
1990 19
1991 29
1992 27
1993 25
1994 30
1995 33
1996 35
1997 51
1998 38
1999 43
2000 48
2001 69
2002 72
2003 84
2004 68
2005 71
2006 65
2007 59
2008 71
2009 59
2010 83
2011 85
2012 95
2013 93
2014 88
2015 76
2016 87
2017 82
2018 84
2019 81
2020 96
2021 78
2022 64
2023 66
2024 15

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2,290 results

Results by year

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Page 1
Metformin-associated lactic acidosis: Current perspectives on causes and risk.
DeFronzo R, Fleming GA, Chen K, Bicsak TA. DeFronzo R, et al. Metabolism. 2016 Feb;65(2):20-9. doi: 10.1016/j.metabol.2015.10.014. Epub 2015 Oct 9. Metabolism. 2016. PMID: 26773926 Free article. Review.
Although metformin has become a drug of choice for the treatment of type 2 diabetes mellitus, some patients may not receive it owing to the risk of lactic acidosis. Metformin, along with other drugs in the biguanide class, increases plasma lactate levels in a plasma …
Although metformin has become a drug of choice for the treatment of type 2 diabetes mellitus, some patients may not receive it owing to the …
Lactic acidosis.
Kraut JA, Madias NE. Kraut JA, et al. N Engl J Med. 2014 Dec 11;371(24):2309-19. doi: 10.1056/NEJMra1309483. N Engl J Med. 2014. PMID: 25494270 Review. No abstract available.
Metformin: When Should We Fear Lactic Acidosis?
Di Mauro S, Filippello A, Scamporrino A, Purrello F, Piro S, Malaguarnera R. Di Mauro S, et al. Int J Mol Sci. 2022 Jul 28;23(15):8320. doi: 10.3390/ijms23158320. Int J Mol Sci. 2022. PMID: 35955455 Free PMC article. Review.
However, since metformin is similar to other members of the same drug family, there is still much concern regarding the risk of lactic acidosis. This article aims to highlight the correlation between the use of metformin and the onset of renal damage or lactic …
However, since metformin is similar to other members of the same drug family, there is still much concern regarding the risk of lactic …
Etiology and Management of Acute Metabolic Acidosis: An Update.
Matyukhin I, Patschan S, Ritter O, Patschan D. Matyukhin I, et al. Kidney Blood Press Res. 2020;45(4):523-531. doi: 10.1159/000507813. Epub 2020 Jul 14. Kidney Blood Press Res. 2020. PMID: 32663831 Free article.
The literature search did not consider diabetic ketoacidosis at all. Lactic acidosis evolves from various conditions, either with or without systemic hypoxia. ...Key Messages: aMA is a frequent and potentially life-threatening complication of various conditions. …
The literature search did not consider diabetic ketoacidosis at all. Lactic acidosis evolves from various conditions, either w …
Sodium bicarbonate for the treatment of lactic acidosis.
Forsythe SM, Schmidt GA. Forsythe SM, et al. Chest. 2000 Jan;117(1):260-7. doi: 10.1378/chest.117.1.260. Chest. 2000. PMID: 10631227 Review.
Lactic acidosis often challenges the intensivist and is associated with a strikingly high mortality. ...Further, given the lack of evidence supporting its use, we cannot condone bicarbonate administration for patients with lactic acidosis, regardless o …
Lactic acidosis often challenges the intensivist and is associated with a strikingly high mortality. ...Further, given the lac …
Sodium bicarbonate therapy in patients with metabolic acidosis.
Adeva-Andany MM, Fernández-Fernández C, Mouriño-Bayolo D, Castro-Quintela E, Domínguez-Montero A. Adeva-Andany MM, et al. ScientificWorldJournal. 2014;2014:627673. doi: 10.1155/2014/627673. Epub 2014 Oct 21. ScientificWorldJournal. 2014. PMID: 25405229 Free PMC article. Review.
Replacement of sodium bicarbonate to patients with sodium bicarbonate loss due to diarrhea or renal proximal tubular acidosis is useful, but there is no definite evidence that sodium bicarbonate administration to patients with acute metabolic acidosis, including diabetic ketoacid …
Replacement of sodium bicarbonate to patients with sodium bicarbonate loss due to diarrhea or renal proximal tubular acidosis is useful, but …
Medication-Induced Hyperlactatemia and Lactic Acidosis: A Systematic Review of the Literature.
Smith ZR, Horng M, Rech MA. Smith ZR, et al. Pharmacotherapy. 2019 Sep;39(9):946-963. doi: 10.1002/phar.2316. Epub 2019 Aug 29. Pharmacotherapy. 2019. PMID: 31361914
Hyperlactatemia and lactic acidosis are two syndromes that are associated with morbidity and mortality. Medication-induced hyperlactatemia and lactic acidosis are diagnoses of exclusion and have the potential to be overlooked. ...
Hyperlactatemia and lactic acidosis are two syndromes that are associated with morbidity and mortality. Medication-induced hyp …
Metformin in patients with type 2 diabetes and kidney disease: a systematic review.
Inzucchi SE, Lipska KJ, Mayo H, Bailey CJ, McGuire DK. Inzucchi SE, et al. JAMA. 2014 Dec 24-31;312(24):2668-75. doi: 10.1001/jama.2014.15298. JAMA. 2014. PMID: 25536258 Free PMC article. Review.
However, the drug is contraindicated in many individuals with impaired kidney function because of concerns of lactic acidosis. OBJECTIVE: To assess the risk of lactic acidosis associated with metformin use in individuals with impaired kidney function. …
However, the drug is contraindicated in many individuals with impaired kidney function because of concerns of lactic acidosis. …
Colchicine poisoning: the dark side of an ancient drug.
Finkelstein Y, Aks SE, Hutson JR, Juurlink DN, Nguyen P, Dubnov-Raz G, Pollak U, Koren G, Bentur Y. Finkelstein Y, et al. Clin Toxicol (Phila). 2010 Jun;48(5):407-14. doi: 10.3109/15563650.2010.495348. Clin Toxicol (Phila). 2010. PMID: 20586571 Review.
Colchicine is excreted into breast milk and considered compatible with lactation. CLINICAL FEATURES: Colchicine poisoning presents in three sequential and usually overlapping phases: 1) 10-24 h after ingestion - gastrointestinal phase mimicking gastroenteritis may be absen …
Colchicine is excreted into breast milk and considered compatible with lactation. CLINICAL FEATURES: Colchicine poisoning presents in …
OXPHOS-targeting drugs in oncology: new perspectives.
Kalyanaraman B, Cheng G, Hardy M, You M. Kalyanaraman B, et al. Expert Opin Ther Targets. 2023 Jul-Dec;27(10):939-952. doi: 10.1080/14728222.2023.2261631. Epub 2023 Oct 30. Expert Opin Ther Targets. 2023. PMID: 37736880 Review.
Patients who were administered the drug developed peripheral neuropathy and other complications (lactic acidosis), resulting in dose reduction. At lower doses, this drug was not effective. Subsequently, the clinical trial was terminated. The investigat …
Patients who were administered the drug developed peripheral neuropathy and other complications (lactic acidosis), resulting i …
2,290 results