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Page 1
The clinical consequences of heterogeneity within and between different diabetes types.
Redondo MJ, Hagopian WA, Oram R, Steck AK, Vehik K, Weedon M, Balasubramanyam A, Dabelea D. Redondo MJ, et al. Diabetologia. 2020 Oct;63(10):2040-2048. doi: 10.1007/s00125-020-05211-7. Epub 2020 Sep 7. Diabetologia. 2020. PMID: 32894314 Free PMC article. Review.
Within type 1 diabetes, endotypes have been discovered based on demographic (e.g. age at diagnosis, race/ethnicity), genetic, immunological, histopathological, metabolic and/or clinical course characteristics, with implications for disease prediction, prevention, diagnosis …
Within type 1 diabetes, endotypes have been discovered based on demographic (e.g. age at diagnosis, race/ethnicity), genetic, immunological, …
Type 1 Diabetes-related Autoantibodies in Different Forms of Diabetes.
Sørgjerd EP. Sørgjerd EP. Curr Diabetes Rev. 2019;15(3):199-204. doi: 10.2174/1573399814666180730105351. Curr Diabetes Rev. 2019. PMID: 30058495 Review.
Autoantibodies against Glutamic Acid Decarboxylase (GADA), insulinoma antigen-2 (IA- 2A), insulin (IAA) and the most recently Zinc Transporter 8 (ZnT8A) are one of the most reliable biomarkers for autoimmune diabetes in both children and adults. They are today the only biomarkers …
Autoantibodies against Glutamic Acid Decarboxylase (GADA), insulinoma antigen-2 (IA- 2A), insulin (IAA) and the most recently Zinc Transport …
Anti-Islet Autoantibodies in Type 1 Diabetes.
Kawasaki E. Kawasaki E. Int J Mol Sci. 2023 Jun 11;24(12):10012. doi: 10.3390/ijms241210012. Int J Mol Sci. 2023. PMID: 37373160 Free PMC article. Review.
Anti-islet autoantibodies serve as key markers in immune-mediated type 1 diabetes (T1D) and slowly progressive T1D (SPIDDM), also known as latent autoimmune diabetes in adults (LADA). Autoantibodies to insulin (IAA), glutamic acid decarboxylase …
Anti-islet autoantibodies serve as key markers in immune-mediated type 1 diabetes (T1D) and slowly progressive T1D (SPIDDM), also known as …
Childhood adiposity and novel subtypes of diabetes in adults: a Mendelian randomisation and genome-wide genetic correlation study.
Wei Y, Zhan Y, Carlsson S. Wei Y, et al. Lancet Glob Health. 2023 Mar;11 Suppl 1:S1. doi: 10.1016/S2214-109X(23)00086-4. Lancet Glob Health. 2023. PMID: 36866468 Free article.
METHODS: The Mendelian randomisation and genetic correlation analyses were based on summary statistics from European genome-wide association studies of childhood body size (n=453 169), adult BMI (n=359 983), latent autoimmune diabetes in adults …
METHODS: The Mendelian randomisation and genetic correlation analyses were based on summary statistics from European genome-wide association …
Birthweight, BMI in adulthood and latent autoimmune diabetes in adults: a Mendelian randomisation study.
Wei Y, Zhan Y, Löfvenborg JE, Tuomi T, Carlsson S. Wei Y, et al. Diabetologia. 2022 Sep;65(9):1510-1518. doi: 10.1007/s00125-022-05725-2. Epub 2022 May 23. Diabetologia. 2022. PMID: 35606578 Free PMC article.
AIMS/HYPOTHESIS: Observational studies have found an increased risk of latent autoimmune diabetes in adults (LADA) associated with low birthweight and adult overweight/obese status. ...RESULTS: Genetically determined own birthweight was i …
AIMS/HYPOTHESIS: Observational studies have found an increased risk of latent autoimmune diabetes in a …
Antioxidant Nutrients and Risk of Latent Autoimmune Diabetes in Adults and Type 2 Diabetes: A Swedish Case-Control Study and Mendelian Randomization Analysis.
Lampousi AM, Löfvenborg JE, Ahlqvist E, Tuomi T, Wolk A, Carlsson S. Lampousi AM, et al. Nutrients. 2023 May 30;15(11):2546. doi: 10.3390/nu15112546. Nutrients. 2023. PMID: 37299509 Free PMC article.
Antioxidant vitamins C and E are inversely associated with type 1 diabetes (T1D). We investigated if antioxidants are also associated with latent autoimmune diabetes in adults (LADA), with low (LADA(low)) and high (LADA(high)) autoantibody level …
Antioxidant vitamins C and E are inversely associated with type 1 diabetes (T1D). We investigated if antioxidants are also associated with …
Childhood adiposity and novel subtypes of adult-onset diabetes: a Mendelian randomisation and genome-wide genetic correlation study.
Wei Y, Richardson TG, Zhan Y, Carlsson S. Wei Y, et al. Diabetologia. 2023 Jun;66(6):1052-1056. doi: 10.1007/s00125-023-05883-x. Epub 2023 Feb 27. Diabetologia. 2023. PMID: 36843089 Free PMC article.
METHODS: We performed MR analysis using data from European genome-wide association studies of childhood adiposity, latent autoimmune diabetes in adults (LADA, proxy for severe autoimmune diabetes), severe insulin-deficient diabetes (SIDD), sever …
METHODS: We performed MR analysis using data from European genome-wide association studies of childhood adiposity, latent autoimmu …
Prevalence and factors associated with latent autoimmune diabetes in adults (LADA): a cross-sectional study.
Manisha AM, Shangali AR, Mfinanga SG, Mbugi EV. Manisha AM, et al. BMC Endocr Disord. 2022 Jul 8;22(1):175. doi: 10.1186/s12902-022-01089-1. BMC Endocr Disord. 2022. PMID: 35804315 Free PMC article.
BACKGROUND: The Latent Autoimmune Diabetes in Adults (LADA) is a slowly progressive Type 1 diabetes subgroup with onset during middle age. ...Neither neuropathy, nephropathy, nor Diabetic Mellitus (D.M.) foot syndrome was observed among L …
BACKGROUND: The Latent Autoimmune Diabetes in Adults (LADA) is a slowly progressive Type 1 diabetes subgr …
Clinical value of lymphocyte count in autoimmune diabetic nephropathy.
Xiang Z, Liu W, Fu S, Hu J, Yang Y. Xiang Z, et al. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023 Nov 28;48(11):1639-1649. doi: 10.11817/j.issn.1672-7347.2023.230110. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023. PMID: 38432854 Free PMC article.
METHODS: The clinical data of 226 patients with Type 1 diabetes (T1D) and 79 patients with latent autoimmune diabetes in adults (LADA) were retrospectively studied and stratified according to the urinary albumin to creatinine ratio (ACR). ...Ana …
METHODS: The clinical data of 226 patients with Type 1 diabetes (T1D) and 79 patients with latent autoimmune diabetes …
New Insights into the Genetics of Latent Autoimmune Diabetes in Adults.
Andersen MK. Andersen MK. Curr Diab Rep. 2020 Jul 28;20(9):43. doi: 10.1007/s11892-020-01330-y. Curr Diab Rep. 2020. PMID: 32725517 Review.
PURPOSE OF REVIEW: Diabetes is a spectrum of clinical manifestations, including latent autoimmune diabetes in adults (LADA). However, it has been questioned whether LADA exists or simply is a group of misclassified type 1 diabetes (T1D) and type …
PURPOSE OF REVIEW: Diabetes is a spectrum of clinical manifestations, including latent autoimmune diabetes in …
144 results