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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1950 3
1952 6
1953 4
1954 9
1955 6
1956 9
1957 5
1958 7
1959 4
1960 1
1961 1
1962 2
1963 3
1964 8
1965 19
1966 46
1967 51
1968 86
1969 95
1970 150
1971 163
1972 146
1973 212
1974 238
1975 1793
1976 1990
1977 1903
1978 1944
1979 2194
1980 2435
1981 2635
1982 2978
1983 3657
1984 4143
1985 4502
1986 4694
1987 5004
1988 5295
1989 6351
1990 6919
1991 7363
1992 8062
1993 8769
1994 10017
1995 10811
1996 11819
1997 12446
1998 13734
1999 14528
2000 15591
2001 16349
2002 17138
2003 19461
2004 20698
2005 22778
2006 23917
2007 25408
2008 26794
2009 28716
2010 31606
2011 34779
2012 37178
2013 39446
2014 40873
2015 41684
2016 42419
2017 43874
2018 44748
2019 46681
2020 48993
2021 48826
2022 47664
2023 42115
2024 18508

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875,288 results

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Quoted phrase not found in phrase index: "Lesion with Diameter of 4 mm or More"
Page 1
Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial. Nocturnal Oxygen Therapy Trial Group.
[No authors listed] [No authors listed] Ann Intern Med. 1980 Sep;93(3):391-8. doi: 10.7326/0003-4819-93-3-391. Ann Intern Med. 1980. PMID: 6776858 Clinical Trial.
At six centers, 203 patients with hypoxemic chronic obstructive lung disease were randomly allocated to either continuous oxygen (O2) therapy or 12-hour nocturnal O2 therapy and followed for at least 12 months (mean, 19.3 months). ...
At six centers, 203 patients with hypoxemic chronic obstructive lung disease were randomly allocated to either continuous oxygen (O2) …
Randomization and allocation concealment: a practical guide for researchers.
Doig GS, Simpson F. Doig GS, et al. J Crit Care. 2005 Jun;20(2):187-91; discussion 191-3. doi: 10.1016/j.jcrc.2005.04.005. J Crit Care. 2005. PMID: 16139163
Although the randomized controlled trial is the most important tool currently available to objectively assess the impact of new treatments, the act of randomization itself is often poorly conducted and incompletely reported. ...We will outline how to prepare …
Although the randomized controlled trial is the most important tool currently available to objectively assess the impact of ne …
Eliminating bias in randomized controlled trials: importance of allocation concealment and masking.
Viera AJ, Bangdiwala SI. Viera AJ, et al. Fam Med. 2007 Feb;39(2):132-7. Fam Med. 2007. PMID: 17273956 Free article.
Randomization in randomized controlled trials involves more than generation of a random sequence by which to assign subjects. ...In contrast to allocation concealment, masking cannot always be incorporated into a randomized controlled trial. Bot …
Randomization in randomized controlled trials involves more than generation of a random sequence by which to assign sub …
How to randomize.
Vickers AJ. Vickers AJ. J Soc Integr Oncol. 2006 Fall;4(4):194-8. doi: 10.2310/7200.2006.023. J Soc Integr Oncol. 2006. PMID: 17022927 Free PMC article. Review.
Many investigators do not pay sufficient attention to randomization procedures, and several studies have shown that only a fraction of trial reports describe randomization adequately. ...The use of telephone randomization and opaque envelopes has been …
Many investigators do not pay sufficient attention to randomization procedures, and several studies have shown that only a fraction o …
Re-randomization tests in clinical trials.
Proschan MA, Dodd LE. Proschan MA, et al. Stat Med. 2019 May 30;38(12):2292-2302. doi: 10.1002/sim.8093. Epub 2019 Jan 22. Stat Med. 2019. PMID: 30672002 Review.
One straightforward analysis method is a re-randomization test that fixes outcome data and creates a reference distribution for the test statistic by repeatedly re-randomizing according to the same randomization method used in the trial. This article r …
One straightforward analysis method is a re-randomization test that fixes outcome data and creates a reference distribution for the t …
Randomization methods in emergency setting trials: a descriptive review.
Corbett MS, Moe-Byrne T, Oddie S, McGuire W. Corbett MS, et al. Res Synth Methods. 2016 Mar;7(1):46-54. doi: 10.1002/jrsm.1163. Epub 2015 Sep 2. Res Synth Methods. 2016. PMID: 26333419 Free PMC article. Review.
Clinical heterogeneity and poor reporting limited the assessment of trial recruitment outcomes. ...Clinical heterogeneity across trials within reviews, coupled with limited availability of relevant trial accrual data, meant it was not possible to adequ …
Clinical heterogeneity and poor reporting limited the assessment of trial recruitment outcomes. ...Clinical heterogenei …
'Mendelian randomization': an approach for exploring causal relations in epidemiology.
Gupta V, Walia GK, Sachdeva MP. Gupta V, et al. Public Health. 2017 Apr;145:113-119. doi: 10.1016/j.puhe.2016.12.033. Epub 2017 Jan 21. Public Health. 2017. PMID: 28359378 Review.
OBJECTIVES: To assess the current status of Mendelian randomization (MR) approach in effectively influencing the observational epidemiology for examining causal relationships. ...RESULTS: Observational epidemiological studies have repeatedly produced several beneficiary as …
OBJECTIVES: To assess the current status of Mendelian randomization (MR) approach in effectively influencing the observational epidem …
Random allocation in controlled clinical trials: a review.
Egbewale BE. Egbewale BE. J Pharm Pharm Sci. 2014;17(2):248-53. doi: 10.18433/j3sw36. J Pharm Pharm Sci. 2014. PMID: 24934553 Free article. Review.
In some circles, opinions are also divided on the strength and weaknesses of each of the random allocation strategies. This review provides an update on various random allocation techniques so as to correct existing misconceptions on this all important procedure. ME …
In some circles, opinions are also divided on the strength and weaknesses of each of the random allocation strategies. This review pr …
The use of minimization in clinical trials.
Taves DR. Taves DR. Contemp Clin Trials. 2010 Mar;31(2):180-4. doi: 10.1016/j.cct.2009.12.005. Epub 2010 Jan 8. Contemp Clin Trials. 2010. PMID: 20060500 Review.
In the past 10 years usage has increased three fold over the previous decade but is still less than 2% of clinical trials. None of the studies makes maximum use of minimization and they are not following good reporting practices. ...The two types of analyses are distinguis …
In the past 10 years usage has increased three fold over the previous decade but is still less than 2% of clinical trials. None of th …
Hypothesis testing in clinical trials.
Green SB. Green SB. Hematol Oncol Clin North Am. 2000 Aug;14(4):785-95, vii-viii. doi: 10.1016/s0889-8588(05)70311-7. Hematol Oncol Clin North Am. 2000. PMID: 10949773 Review.
In designing and analyzing any clinical trial, two issues related to patient heterogeneity must be considered: (1) the effect of chance and (2) the effect of bias. These issues are addressed by enrolling adequate numbers of patients in the study and using randomi …
In designing and analyzing any clinical trial, two issues related to patient heterogeneity must be considered: (1) the effect …
875,288 results
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