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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1993 1
1996 2
1997 1
1999 1
2000 3
2001 1
2002 3
2003 3
2004 1
2005 5
2006 7
2007 7
2008 6
2009 5
2010 10
2011 6
2012 13
2013 17
2014 9
2015 15
2016 15
2017 18
2018 20
2019 27
2020 34
2021 41
2022 43
2023 40
2024 19

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324 results

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Page 1
Dementia Caregiver Burden: a Research Update and Critical Analysis.
Cheng ST. Cheng ST. Curr Psychiatry Rep. 2017 Aug 10;19(9):64. doi: 10.1007/s11920-017-0818-2. Curr Psychiatry Rep. 2017. PMID: 28795386 Free PMC article. Review.
RECENT FINDINGS: As a group, neuropsychiatric symptoms are most predictive of caregiver burden and depression regardless of dementia diagnosis, but the effects appear to be driven primarily by disruptive behaviors (e.g., agitation, aggression, disinhibition), followed by d …
RECENT FINDINGS: As a group, neuropsychiatric symptoms are most predictive of caregiver burden and depression regardless of dementia …
Alpha Synuclein: Neurodegeneration and Inflammation.
Forloni G. Forloni G. Int J Mol Sci. 2023 Mar 21;24(6):5914. doi: 10.3390/ijms24065914. Int J Mol Sci. 2023. PMID: 36982988 Free PMC article. Review.
Differences in microglia and astrocyte activation have also been observed when in vivo the presence of alpha-Syn oligomers has been combined with a lasting peripheral inflammatory effect. ...
Differences in microglia and astrocyte activation have also been observed when in vivo the presence of alpha-Syn oligomers has been c …
Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis.
Stinton C, McKeith I, Taylor JP, Lafortune L, Mioshi E, Mak E, Cambridge V, Mason J, Thomas A, O'Brien JT. Stinton C, et al. Am J Psychiatry. 2015 Aug 1;172(8):731-42. doi: 10.1176/appi.ajp.2015.14121582. Epub 2015 Jun 18. Am J Psychiatry. 2015. PMID: 26085043 Free article. Review.
The authors used the search terms "Lewy or parkinson" and "dementia" through March 2015 and used the following inclusion criteria: participants with diagnoses of Lewy body dementia, dementia with Lewy bodies, or Parkinson's disease dementia (or participants' …
The authors used the search terms "Lewy or parkinson" and "dementia" through March 2015 and used the following inclusion criteria: participa …
CD4(+) T cells contribute to neurodegeneration in Lewy body dementia.
Gate D, Tapp E, Leventhal O, Shahid M, Nonninger TJ, Yang AC, Strempfl K, Unger MS, Fehlmann T, Oh H, Channappa D, Henderson VW, Keller A, Aigner L, Galasko DR, Davis MM, Poston KL, Wyss-Coray T. Gate D, et al. Science. 2021 Nov 12;374(6569):868-874. doi: 10.1126/science.abf7266. Epub 2021 Oct 14. Science. 2021. PMID: 34648304 Free PMC article.
Recent studies indicate that the adaptive immune system plays a role in Lewy body dementia (LBD). However, the mechanism regulating T cell brain homing in LBD is unknown. Here, we observed T cells adjacent to Lewy bodies and dopaminergic neurons in pos …
Recent studies indicate that the adaptive immune system plays a role in Lewy body dementia (LBD). However, the mechanis …
Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function.
Rosoff DB, Bell AS, Jung J, Wagner J, Mavromatis LA, Lohoff FW. Rosoff DB, et al. J Am Coll Cardiol. 2022 Aug 16;80(7):653-662. doi: 10.1016/j.jacc.2022.05.041. J Am Coll Cardiol. 2022. PMID: 35953131 Free article.
RESULTS: Using data from a combined sample of 740,000 participants, we observed a neutral cognitive profile related to genetic PCSK9 inhibition, with no significant effects on cognitive performance, memory performance, or cortical surface area. ...Neither PCSK9 nor HMGCR i …
RESULTS: Using data from a combined sample of 740,000 participants, we observed a neutral cognitive profile related to genetic PCSK9 …
ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias.
Martens YA, Zhao N, Liu CC, Kanekiyo T, Yang AJ, Goate AM, Holtzman DM, Bu G. Martens YA, et al. Neuron. 2022 Apr 20;110(8):1304-1317. doi: 10.1016/j.neuron.2022.03.004. Epub 2022 Mar 16. Neuron. 2022. PMID: 35298921 Free PMC article. Review.
The epsilon4 allele of the apolipoprotein E gene (APOE4) is a strong genetic risk factor for Alzheimer's disease (AD) and several other neurodegenerative conditions, including Lewy body dementia (LBD). The three APOE alleles encode protein isoforms that diffe …
The epsilon4 allele of the apolipoprotein E gene (APOE4) is a strong genetic risk factor for Alzheimer's disease (AD) and several other neur …
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.
Chia R, Sabir MS, Bandres-Ciga S, Saez-Atienzar S, Reynolds RH, Gustavsson E, Walton RL, Ahmed S, Viollet C, Ding J, Makarious MB, Diez-Fairen M, Portley MK, Shah Z, Abramzon Y, Hernandez DG, Blauwendraat C, Stone DJ, Eicher J, Parkkinen L, Ansorge O, Clark L, Honig LS, Marder K, Lemstra A, St George-Hyslop P, Londos E, Morgan K, Lashley T, Warner TT, Jaunmuktane Z, Galasko D, Santana I, Tienari PJ, Myllykangas L, Oinas M, Cairns NJ, Morris JC, Halliday GM, Van Deerlin VM, Trojanowski JQ, Grassano M, Calvo A, Mora G, Canosa A, Floris G, Bohannan RC, Brett F, Gan-Or Z, Geiger JT, Moore A, May P, Krüger R, Goldstein DS, Lopez G, Tayebi N, Sidransky E; American Genome Center; Norcliffe-Kaufmann L, Palma JA, Kaufmann H, Shakkottai VG, Perkins M, Newell KL, Gasser T, Schulte C, Landi F, Salvi E, Cusi D, Masliah E, Kim RC, Caraway CA, Monuki ES, Brunetti M, Dawson TM, Rosenthal LS, Albert MS, Pletnikova O, Troncoso JC, Flanagan ME, Mao Q, Bigio EH, Rodríguez-Rodríguez E, Infante J, Lage C, González-Aramburu I, Sanchez-Juan P, Ghetti B, Keith J, Black SE, Masellis M, Rogaeva E, Duyckaerts C, Brice A, Lesage S, Xiromerisiou G, Barrett MJ, Tilley BS, Gentleman S, Logroscino G, Serrano GE, … See abstract for full author list ➔ Chia R, et al. Nat Genet. 2021 Mar;53(3):294-303. doi: 10.1038/s41588-021-00785-3. Epub 2021 Feb 15. Nat Genet. 2021. PMID: 33589841 Free PMC article.
The genetic basis of Lewy body dementia (LBD) is not well understood. Here, we performed whole-genome sequencing in large cohorts of LBD cases and neurologically healthy controls to study the genetic architecture of this understudied form of dementia, and to …
The genetic basis of Lewy body dementia (LBD) is not well understood. Here, we performed whole-genome sequencing in lar …
Mini-Mental State Examination (MMSE) for the early detection of dementia in people with mild cognitive impairment (MCI).
Arevalo-Rodriguez I, Smailagic N, Roqué-Figuls M, Ciapponi A, Sanchez-Perez E, Giannakou A, Pedraza OL, Bonfill Cosp X, Cullum S. Arevalo-Rodriguez I, et al. Cochrane Database Syst Rev. 2021 Jul 27;7(7):CD010783. doi: 10.1002/14651858.CD010783.pub3. Cochrane Database Syst Rev. 2021. PMID: 34313331 Free PMC article.
We used acceptable and commonly used reference standards for dementia in general, Alzheimer's dementia, Lewy body dementia, vascular dementia and frontotemporal dementia. ...It is also important to assess if a set of tests, rather than an isolated one, may be …
We used acceptable and commonly used reference standards for dementia in general, Alzheimer's dementia, Lewy body dementia …
Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations.
Creavin ST, Wisniewski S, Noel-Storr AH, Trevelyan CM, Hampton T, Rayment D, Thom VM, Nash KJ, Elhamoui H, Milligan R, Patel AS, Tsivos DV, Wing T, Phillips E, Kellman SM, Shackleton HL, Singleton GF, Neale BE, Watton ME, Cullum S. Creavin ST, et al. Cochrane Database Syst Rev. 2016 Jan 13;2016(1):CD011145. doi: 10.1002/14651858.CD011145.pub2. Cochrane Database Syst Rev. 2016. PMID: 26760674 Free PMC article. Review.
SELECTION CRITERIA: We included studies that compared the 11-item (maximum score 30) MMSE test (at any cut point) in people who had not undergone prior testing versus a commonly accepted clinical reference standard for all-cause dementia and subtypes (Alzheimer disease dem …
SELECTION CRITERIA: We included studies that compared the 11-item (maximum score 30) MMSE test (at any cut point) in people who had n …
Predicting amyloid PET and tau PET stages with plasma biomarkers.
Jack CR, Wiste HJ, Algeciras-Schimnich A, Figdore DJ, Schwarz CG, Lowe VJ, Ramanan VK, Vemuri P, Mielke MM, Knopman DS, Graff-Radford J, Boeve BF, Kantarci K, Cogswell PM, Senjem ML, Gunter JL, Therneau TM, Petersen RC. Jack CR, et al. Brain. 2023 May 2;146(5):2029-2044. doi: 10.1093/brain/awad042. Brain. 2023. PMID: 36789483 Free PMC article.
Our objectives were, first, to examine approaches for staging amyloid and tau PET and, second, to examine prediction of amyloid and tau PET stages using plasma biomarkers. Participants (n = 1136) were enrolled in either the Mayo Clinic Study of Aging or the Alzheimer's Dis …
Our objectives were, first, to examine approaches for staging amyloid and tau PET and, second, to examine prediction of amyloid and t …
324 results