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Lhermitte-Duclos Disease: A Rare Lesion with Variable Presentations and Obscure Histopathology.
Önder E, Arikök AT, Türkoğlu E, Alper M. Önder E, et al. Turk Patoloji Derg. 2018;34(1):92-99. doi: 10.5146/tjpath.2014.01283. Turk Patoloji Derg. 2018. PMID: 25371023 Free article.
Frozen sections of one case did not reveal diagnostic findings. The vacuolar change observed in the paraffin sections was obscure in the frozen. Pathological diagnosis of Lhermitte-Duclos disease can be extremely difficult in the absence of proper clin …
Frozen sections of one case did not reveal diagnostic findings. The vacuolar change observed in the paraffin sections was obscure in …
Lhermitte-Duclos disease: Clinical study with long-term follow-up in a single institution.
Wang Q, Zhang S, Cheng J, Liu W, Hui X. Wang Q, et al. Clin Neurol Neurosurg. 2017 Nov;162:53-58. doi: 10.1016/j.clineuro.2017.09.007. Epub 2017 Sep 9. Clin Neurol Neurosurg. 2017. PMID: 28938107
Average tumor size was 629.3mm in its maximal diameter (range, 50-84mm). Tonsillar herniation and preoperative hydrocephalus were observed in 9/12 and 12/12 patients. Four of them confirmed the diagnosis of CS. ...Total resection is difficult due to the indistinct tumor ma …
Average tumor size was 629.3mm in its maximal diameter (range, 50-84mm). Tonsillar herniation and preoperative hydrocephalus were observe …
Lhermitte-Duclos disease is a clinical manifestation of Cowden's syndrome.
Vantomme N, Van Calenbergh F, Goffin J, Sciot R, Demaerel P, Plets C. Vantomme N, et al. Surg Neurol. 2001 Sep;56(3):201-4; discussion 204-5. doi: 10.1016/s0090-3019(01)00552-3. Surg Neurol. 2001. PMID: 11597654 Review.
BACKGROUND: Lhermitte-Duclos disease (LDD) is a hamartomatous overgrowth of cerebellar ganglion cells, which replace granular cells and Purkinje cells. ...Only in the youngest patient, a 5-year-old boy, were no cutaneous or other signs found, despite extensiv …
BACKGROUND: Lhermitte-Duclos disease (LDD) is a hamartomatous overgrowth of cerebellar ganglion cells, which replace gr …
Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway.
Abel TW, Baker SJ, Fraser MM, Tihan T, Nelson JS, Yachnis AT, Bouffard JP, Mena H, Burger PC, Eberhart CG. Abel TW, et al. J Neuropathol Exp Neurol. 2005 Apr;64(4):341-9. doi: 10.1093/jnen/64.4.341. J Neuropathol Exp Neurol. 2005. PMID: 15835270 Review.
Lhermitte-Duclos disease (LDD) is a rare cerebellar tumor associated with Cowden disease (CD) and germline mutations in the PTEN gene. ...Histopathologically, in addition to the classical findings of LDD, we observed prominent vascular proliferation an …
Lhermitte-Duclos disease (LDD) is a rare cerebellar tumor associated with Cowden disease (CD) and germline mutations in …
Cerebellar phenotypes in germline PTEN mutation carriers.
Gambini D, Ferrero S, Bulfamante G, Pisani L, Corbo M, Kuhn E. Gambini D, et al. Neuropathol Appl Neurobiol. 2024 Apr;50(2):e12970. doi: 10.1111/nan.12970. Neuropathol Appl Neurobiol. 2024. PMID: 38504418 Review.
Cerebellar involvement in PHTS patients has been long known due to the development of a pathognomonic cerebellar hamartoma (known as dysplastic gangliocytoma of the cerebellum or Lhermitte-Duclos disease). Recently, a crucial role of the cerebellum has been h …
Cerebellar involvement in PHTS patients has been long known due to the development of a pathognomonic cerebellar hamartoma (known as dysplas …
Recurrent Lhermitte-Duclos disease--case report.
Hashimoto H, Iida J, Masui K, Nishi N, Sakaki T. Hashimoto H, et al. Neurol Med Chir (Tokyo). 1997 Sep;37(9):692-6. doi: 10.2176/nmc.37.692. Neurol Med Chir (Tokyo). 1997. PMID: 9330535 Free article. Review.
A 43-year-old male presented with recurrent Lhermitte-Duclos disease (LDD), a rare pathological entity of the cerebellum of which the etiology is still controversial. ...Recurrence of LDD is not as rare as generally assumed. Patients with LDD require long-ter …
A 43-year-old male presented with recurrent Lhermitte-Duclos disease (LDD), a rare pathological entity of the cerebellu …
Lhermitte - Duclos disease with syrinx: case report and literature review.
Nayil K, Wani M, Ramzan A, Shaheen F, Lone I, Wani A. Nayil K, et al. Turk Neurosurg. 2011;21(4):651-4. Turk Neurosurg. 2011. PMID: 22194132 Free article. Review.
BACKGROUND: Lhermitte-Duclos disease is typified by a hamartomatous lesion of the cerebellum. ...CASE REPORT: We report an 18-year-old female patient who presented to us with history of headache and gait ataxia and was observed to have Lhermitte …
BACKGROUND: Lhermitte-Duclos disease is typified by a hamartomatous lesion of the cerebellum. ...CASE REPORT: We report …
An update on the CNS manifestations of brain tumor polyposis syndromes.
Kim B, Tabori U, Hawkins C. Kim B, et al. Acta Neuropathol. 2020 Apr;139(4):703-715. doi: 10.1007/s00401-020-02124-y. Epub 2020 Jan 22. Acta Neuropathol. 2020. PMID: 31970492 Review.
Tumor specificity does exist as medulloblastoma occur in FAP, LFS and CMMRD while glioma are most commonly seen in all replication repair-deficient genes and LFS. Choroid plexus carcinoma is strictly observed in LFS while Cowden syndrome patients develop Lhermitte …
Tumor specificity does exist as medulloblastoma occur in FAP, LFS and CMMRD while glioma are most commonly seen in all replication repair-de …
Postoperative cerebellar mutism in adult patients with Lhermitte-Duclos disease.
Afshar-Oromieh A, Linhart H, Podlesek D, Schrempf W, Schackert G, Krex D. Afshar-Oromieh A, et al. Neurosurg Rev. 2010 Oct;33(4):401-8. doi: 10.1007/s10143-010-0278-1. Epub 2010 Jul 29. Neurosurg Rev. 2010. PMID: 20668902 Review.
We also report two illustrative cases of CM following surgical treatment of Lhermitte-Duclos disease (LDD; dysplastic gangliocytoma) in two adult patients. ...Despite the severity, CM carries a favorable prognosis and generally resolves within a few months.To …
We also report two illustrative cases of CM following surgical treatment of Lhermitte-Duclos disease (LDD; dysplastic g …
Dysplastic gangliocytoma (Lhermitte-Duclos disease) associated with Cowden disease: report of a case and review of the literature for the genetic relationship between the two diseases.
Murata J, Tada M, Sawamura Y, Mitsumori K, Abe H, Nagashima K. Murata J, et al. J Neurooncol. 1999 Jan;41(2):129-36. doi: 10.1023/a:1006167421100. J Neurooncol. 1999. PMID: 10222433 Review.
We report a case of dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease, LDD). The patient also had cutaneous and mucosal hamartomas, adenomatous goiter, bilateral breast tumors, and gastrointestinal polyposis, indicating the diagnosis of Cow …
We report a case of dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease, LDD). The patient also had cu …
27 results