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Year Number of Results
1986 1
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2002 2
2003 1
2004 1
2007 2
2008 4
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2012 4
2013 3
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52 results

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Page 1
Diffuse cystic lung diseases.
Ryu JH, Tian X, Baqir M, Xu K. Ryu JH, et al. Front Med. 2013 Sep;7(3):316-27. doi: 10.1007/s11684-013-0269-z. Epub 2013 May 11. Front Med. 2013. PMID: 23666611 Review.
Diffuse lung involvement with cystic lesions can be seen in pulmonary lymphangioleiomyomatosis, pulmonary Langerhans' cell histiocytosis, lymphoid interstitial pneumonia, Birt-Hogg-Dube syndrome, amyloidosis, light chain deposition disease, honeycomb l …
Diffuse lung involvement with cystic lesions can be seen in pulmonary lymphangioleiomyomatosis, pulmonary Langerhans' cell histiocytosis, ly …
Light chain deposition disease with renal involvement: clinical characteristics and prognostic factors.
Pozzi C, D'Amico M, Fogazzi GB, Curioni S, Ferrario F, Pasquali S, Quattrocchio G, Rollino C, Segagni S, Locatelli F. Pozzi C, et al. Am J Kidney Dis. 2003 Dec;42(6):1154-63. doi: 10.1053/j.ajkd.2003.08.040. Am J Kidney Dis. 2003. PMID: 14655186 Review.
BACKGROUND: Light chain deposition disease (LCDD) is characterized by the tissue deposition of monotypical immunoglobulin light chains (LCs). ...While kappa-LC deposition was more frequently associated with nodular sclerosing glomerulopathy, histologic …
BACKGROUND: Light chain deposition disease (LCDD) is characterized by the tissue deposition of monotypical immun …
Coexistence of amyloidosis and light chain deposition disease in the heart.
Sobue Y, Takemura G, Kawamura S, Yano T, Kanamori H, Morimoto SI, Matsuo H. Sobue Y, et al. Cardiovasc Pathol. 2021 Mar-Apr;51:107315. doi: 10.1016/j.carpath.2020.107315. Epub 2020 Nov 29. Cardiovasc Pathol. 2021. PMID: 33264681
There are few reports on the coexistence of cardiac amyloid light-chain (AL) amyloidosis and light chain deposition disease (LCDD), despite their similar pathophysiologies caused by plasma-cell dyscrasia. ...In specimens prepared for electron microscop …
There are few reports on the coexistence of cardiac amyloid light-chain (AL) amyloidosis and light chain deposition
IgG Subclass Staining in Routine Renal Biopsy Material.
Hemminger J, Nadasdy G, Satoskar A, Brodsky SV, Nadasdy T. Hemminger J, et al. Am J Surg Pathol. 2016 May;40(5):617-26. doi: 10.1097/PAS.0000000000000605. Am J Surg Pathol. 2016. PMID: 26848798 Review.
We found that monoclonality of IgG deposits cannot always be reliably determined on the basis of kappa and lambda light chain staining alone, particularly if concomitant (frequently nonspecific) IgM staining is present. In IgG heavy and heavy and light chain depo
We found that monoclonality of IgG deposits cannot always be reliably determined on the basis of kappa and lambda light chain staining alone …
Role of the mechanisms for antibody repertoire diversification in monoclonal light chain deposition disorders: when a friend becomes foe.
Del Pozo-Yauner L, Herrera GA, Perez Carreon JI, Turbat-Herrera EA, Rodriguez-Alvarez FJ, Ruiz Zamora RA. Del Pozo-Yauner L, et al. Front Immunol. 2023 Jul 13;14:1203425. doi: 10.3389/fimmu.2023.1203425. eCollection 2023. Front Immunol. 2023. PMID: 37520549 Free PMC article. Review.
This places the light chain out of the protective context provided by the quaternary structure of the antibody, increasing the risk of misfolding and aggregation due to destabilizing somatic mutations. Light chain-derived (AL) amyloidosis, light chain deposition
This places the light chain out of the protective context provided by the quaternary structure of the antibody, increasing the risk of misfo …
Kidney and liver involvement in monoclonal light chain disorders.
Pozzi C, Locatelli F. Pozzi C, et al. Semin Nephrol. 2002 Jul;22(4):319-30. Semin Nephrol. 2002. PMID: 12118397 Review.
Monoclonal light chains (LCs) are responsible for a wide spectrum of renal and hepatic diseases, that above all include amyloid light-chain (AL) amyloidosis and light chain deposition disease (LCDD). Amyloid deposits stain for Congo red on light micros …
Monoclonal light chains (LCs) are responsible for a wide spectrum of renal and hepatic diseases, that above all include amyloid light-chain …
Masson Trichrome and Sulfated Alcian Blue Stains Distinguish Light Chain Deposition Disease From Amyloidosis in the Lung.
Kunnath-Velayudhan S, Larsen BT, Coley SM, De Michele S, Santoriello D, Colby TV, Bhagat G, Saqi A. Kunnath-Velayudhan S, et al. Am J Surg Pathol. 2021 Mar 1;45(3):405-413. doi: 10.1097/PAS.0000000000001593. Am J Surg Pathol. 2021. PMID: 33002919
Light chain deposition disease, characterized by nonamyloidogenic deposits of immunoglobulin light chains, is rare in the lung and possibly underdiagnosed due to low clinical suspicion and lack of readily accessible tests. We encountered a case of pulm
Light chain deposition disease, characterized by nonamyloidogenic deposits of immunoglobulin light chains, is ra
Light chain deposition disease without glomerular proteinuria: a diagnostic challenge for the nephrologist.
Sicard A, Karras A, Goujon JM, Sirac C, Bender S, Labatut D, Callard P, Sarkozy C, Essig M, Vanhille P, Provot F, Nony A, Nochy D, Ronco P, Bridoux F, Touchard G. Sicard A, et al. Nephrol Dial Transplant. 2014 Oct;29(10):1894-902. doi: 10.1093/ndt/gfu045. Epub 2014 Mar 11. Nephrol Dial Transplant. 2014. PMID: 24619059
By light microscopy, tubulo-interstitial lesions were prominent in all patients and focal nodular glomerulosclerosis was only observed in two cases. Identification of LCDD led to initiation of chemotherapy in 12 cases. ...
By light microscopy, tubulo-interstitial lesions were prominent in all patients and focal nodular glomerulosclerosis was only observed
Renal morphologic lesions reminiscent of diabetic nephropathy.
Raparia K, Usman I, Kanwar YS. Raparia K, et al. Arch Pathol Lab Med. 2013 Mar;137(3):351-9. doi: 10.5858/arpa.2012-0243-RA. Arch Pathol Lab Med. 2013. PMID: 23451746 Free article. Review.
CONTEXT: Nodular, intercapillary glomerulosclerotic lesions resembling Kimmelstiel-Wilson nodules commonly observed in diabetic nephropathy can also be seen in patients without any clinical history or evidence of diabetes. OBJECTIVES: To discuss the pathobiology of lesions …
CONTEXT: Nodular, intercapillary glomerulosclerotic lesions resembling Kimmelstiel-Wilson nodules commonly observed in diabetic nephr …
Animal Models of Light Chain Deposition Disease Provide a Better Understanding of Nodular Glomerulosclerosis.
Herrera GA, Turbat-Herrera EA, Teng J. Herrera GA, et al. Nephron. 2016;132(2):119-36. doi: 10.1159/000443282. Epub 2016 Jan 22. Nephron. 2016. PMID: 26794829
BACKGROUND: Light chain deposition disease (LCDD) is a model of glomerulosclerosis. ...RESULTS: The animal models described in this manuscript provide validation for the in-vitro data that have been previously published and expand our appreciation of t …
BACKGROUND: Light chain deposition disease (LCDD) is a model of glomerulosclerosis. ...RESULTS: The animal model …
52 results