Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1965 1
1989 3
1991 1
1993 2
1994 3
1995 3
1996 1
1997 11
1998 7
1999 7
2000 11
2001 13
2002 14
2003 25
2004 23
2005 21
2006 16
2007 17
2008 28
2009 16
2010 27
2011 26
2012 23
2013 30
2014 33
2015 35
2016 37
2017 36
2018 44
2019 41
2020 50
2021 72
2022 61
2023 56
2024 24

Text availability

Article attribute

Article type

Publication date

Search Results

413 results

Results by year

Filters applied: Meta-Analysis, Review, Systematic Review, in the last 10 years. Clear all
Page 1
Lipoic acid metabolism and mitochondrial redox regulation.
Solmonson A, DeBerardinis RJ. Solmonson A, et al. J Biol Chem. 2018 May 18;293(20):7522-7530. doi: 10.1074/jbc.TM117.000259. Epub 2017 Nov 30. J Biol Chem. 2018. PMID: 29191830 Free PMC article. Review.
Lipoic acid is an essential cofactor for mitochondrial metabolism and is synthesized de novo using intermediates from mitochondrial fatty-acid synthesis type II, S-adenosylmethionine and iron-sulfur clusters. ...Many of these dehydrogenases are regulated by reactive …
Lipoic acid is an essential cofactor for mitochondrial metabolism and is synthesized de novo using intermediates from mitochon …
Alpha Lipoic Acid.
[No authors listed] [No authors listed] 2023 May 3. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2023 May 3. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 37184197 Free Books & Documents. Review.
Alpha lipoic acid is a natural occurring essential fatty acid that is synthesized intracellularly, but is also in many foods and absorbed to a variable extent. Alpha lipoic acid is a common ingredient in multivitamin tablets and in dietary supplements …
Alpha lipoic acid is a natural occurring essential fatty acid that is synthesized intracellularly, but is also in many foods a …
Insights on the Use of alpha-Lipoic Acid for Therapeutic Purposes.
Salehi B, Berkay Yılmaz Y, Antika G, Boyunegmez Tumer T, Fawzi Mahomoodally M, Lobine D, Akram M, Riaz M, Capanoglu E, Sharopov F, Martins N, Cho WC, Sharifi-Rad J. Salehi B, et al. Biomolecules. 2019 Aug 9;9(8):356. doi: 10.3390/biom9080356. Biomolecules. 2019. PMID: 31405030 Free PMC article. Review.
alpha-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. ...
alpha-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. ...
Effect of Alpha-Lipoic Acid in the Treatment of Diabetic Neuropathy: A Systematic Review.
Abubaker SA, Alonazy AM, Abdulrahman A. Abubaker SA, et al. Cureus. 2022 Jun 8;14(6):e25750. doi: 10.7759/cureus.25750. eCollection 2022 Jun. Cureus. 2022. PMID: 35812639 Free PMC article. Review.
Novel studies have proposed that the use of antioxidants, including alpha-lipoic acid (-lipoic acid), may represent a beneficial intervention for treating neuropathic pain in diabetic patients. ...All studies found -lipoic acid to be a sa …
Novel studies have proposed that the use of antioxidants, including alpha-lipoic acid (-lipoic acid), may repres …
Efficacy of alpha-lipoic acid in diabetic neuropathy.
Papanas N, Ziegler D. Papanas N, et al. Expert Opin Pharmacother. 2014 Dec;15(18):2721-31. doi: 10.1517/14656566.2014.972935. Epub 2014 Nov 10. Expert Opin Pharmacother. 2014. PMID: 25381809 Review.
AREAS COVERED: The objective of this review is assessment of efficacy and safety of alpha lipoic acid (ALA, also thioctic acid) in pathogenesis-oriented treatment of diabetic neuropathy. ...
AREAS COVERED: The objective of this review is assessment of efficacy and safety of alpha lipoic acid (ALA, also thioctic acid …
Coenzyme Q10 + alpha lipoic acid for chronic COVID syndrome.
Barletta MA, Marino G, Spagnolo B, Bianchi FP, Falappone PCF, Spagnolo L, Gatti P. Barletta MA, et al. Clin Exp Med. 2023 Jul;23(3):667-678. doi: 10.1007/s10238-022-00871-8. Epub 2022 Aug 22. Clin Exp Med. 2023. PMID: 35994177 Free PMC article. Review.
We examined if use of an association of coenzyme Q10 and alpha lipoic acid (Requpero) could reduce chronic covid symptoms. The Requpero study is a prospective observational study in which 174 patients, who had developed chronic-covid syndrome, were divided in two gr …
We examined if use of an association of coenzyme Q10 and alpha lipoic acid (Requpero) could reduce chronic covid symptoms. The …
Alpha-Lipoic Acid and Glucose Metabolism: A Comprehensive Update on Biochemical and Therapeutic Features.
Capece U, Moffa S, Improta I, Di Giuseppe G, Nista EC, Cefalo CMA, Cinti F, Pontecorvi A, Gasbarrini A, Giaccari A, Mezza T. Capece U, et al. Nutrients. 2022 Dec 21;15(1):18. doi: 10.3390/nu15010018. Nutrients. 2022. PMID: 36615676 Free PMC article. Review.
Alpha-lipoic acid (ALA) is a natural compound with antioxidant and pro-oxidant properties which has effects on the regulation of insulin sensitivity and insulin secretion. ...
Alpha-lipoic acid (ALA) is a natural compound with antioxidant and pro-oxidant properties which has effects on the regulation …
Lipoic acid. Kinetics and pluripotent biological properties and derivatives.
Theodosis-Nobelos P, Papagiouvannis G, Tziona P, Rekka EA. Theodosis-Nobelos P, et al. Mol Biol Rep. 2021 Sep;48(9):6539-6550. doi: 10.1007/s11033-021-06643-z. Epub 2021 Aug 22. Mol Biol Rep. 2021. PMID: 34420148 Review.
Lipoic acid (LA) is globally known and its supplements are widely used. ...Furthermore, the safety and the toxicological profile of the compound are commented, together with its stability issues. Mechanisms of lipoic acid intervention in the human body …
Lipoic acid (LA) is globally known and its supplements are widely used. ...Furthermore, the safety and the toxicological profi …
Effects of Oral Alpha-Lipoic Acid Treatment on Diabetic Polyneuropathy: A Meta-Analysis and Systematic Review.
Hsieh RY, Huang IC, Chen C, Sung JY. Hsieh RY, et al. Nutrients. 2023 Aug 18;15(16):3634. doi: 10.3390/nu15163634. Nutrients. 2023. PMID: 37630823 Free PMC article. Review.
Alpha-lipoic acid (ALA) was found to improve the symptoms in patients with diabetic sensorimotor peripheral neuropathy (DSPN) by reducing oxidative stress and ameliorating microcirculation. ...
Alpha-lipoic acid (ALA) was found to improve the symptoms in patients with diabetic sensorimotor peripheral neuropathy (DSPN) …
413 results