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1990 2
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2000 6
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90 results

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Quoted phrase not found in phrase index: "Loss of Chromosome 9p"
Page 1
Impact of Aneuploidy and Chromosome 9p Loss on Tumor Immune Microenvironment and Immune Checkpoint Inhibitor Efficacy in NSCLC.
Alessi JV, Wang X, Elkrief A, Ricciuti B, Li YY, Gupta H, Spurr LF, Rizvi H, Luo J, Pecci F, Lamberti G, Recondo G, Venkatraman D, Di Federico A, Gandhi MM, Vaz VR, Nishino M, Sholl LM, Cherniack AD, Ladanyi M, Price A, Richards AL, Donoghue M, Lindsay J, Sharma B, Turner MM, Pfaff KL, Felt KD, Rodig SJ, Lin X, Meyerson ML, Johnson BE, Christiani DC, Schoenfeld AJ, Awad MM. Alessi JV, et al. J Thorac Oncol. 2023 Nov;18(11):1524-1537. doi: 10.1016/j.jtho.2023.05.019. Epub 2023 May 27. J Thorac Oncol. 2023. PMID: 37247843 Free PMC article.

Compared with NSCLCs without chromosome 9p loss (n = 452), those with 9p loss (n = 154) had a lower ORR (28.1% versus 7.8%, p < 0.0001), a shorter mPFS (4.1 versus 2.3 mo, p < 0.0001), and a shorter mOS (18.0 versus 9.6 mo, p < 0.0001)

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Compared with NSCLCs without chromosome 9p loss (n = 452), those with 9p loss (n = 154) had a lower ORR ( …
Bladder cancer.
Ozen H. Ozen H. Curr Opin Oncol. 1998 May;10(3):273-8. Curr Opin Oncol. 1998. PMID: 9619365 Review.
The most common genetic alteration identified to date in bladder cancer is loss of heterozygosity of chromosome 9, suggesting a possible tumor-suppressor gene on this chromosome. Because none of the Ta tumors showed loss of heterozygosity of 9p, …
The most common genetic alteration identified to date in bladder cancer is loss of heterozygosity of chromosome 9, suggesting …
Loss of Heterozygosity of 9p Is Associated with Poorer Survival in Patients with Gliomas.
Huang T, Li S, Yang Z, Liu J, Han Y. Huang T, et al. Mol Neurobiol. 2016 Nov;53(9):6407-6412. doi: 10.1007/s12035-015-9523-5. Epub 2015 Nov 19. Mol Neurobiol. 2016. PMID: 26582467
The prognostic factors associated with the survival of glioma patients have not been well established. Loss of heterozygosity (LOH) of 9p was known to be a typical molecular signature of gliomas, but it was still unclear whether LOH of 9p was associated with …
The prognostic factors associated with the survival of glioma patients have not been well established. Loss of heterozygosity (LOH) o …
Asbestos, chromosomal deletions, and tumor suppressor gene alterations in human malignant mesothelioma.
Murthy SS, Testa JR. Murthy SS, et al. J Cell Physiol. 1999 Aug;180(2):150-7. doi: 10.1002/(SICI)1097-4652(199908)180:2<150::AID-JCP2>3.0.CO;2-H. J Cell Physiol. 1999. PMID: 10395284 Review.
We highlight the role of asbestos in MM and summarize cytogenetic and molecular genetic findings in this malignancy. The accumulation of numerous clonal chromosomal deletions in most MMs suggests a multistep process of tumorigenesis, characterized by the loss and/or …
We highlight the role of asbestos in MM and summarize cytogenetic and molecular genetic findings in this malignancy. The accumulation of num …
The effects of 3-year growth hormone treatment and body composition in Polish patients with Silver-Russell syndrome.
Świąder-Leśniak A, Jurkiewicz D, Kołodziejczyk H, Kozłowska A, Korpysz A, Szalecki M, Chrzanowska K. Świąder-Leśniak A, et al. Endokrynol Pol. 2023;74(3):285-293. doi: 10.5603/EP.a2023.0042. Epub 2023 Jun 19. Endokrynol Pol. 2023. PMID: 37335065 Free article.
INTRODUCTION: Silver-Russell syndrome (SRS) is characterized by clinical and genetic heterogeneity. SRS is the only disease entity associated with (epi)genetic abnormalities of 2 different chromosomes: 7 and 11. In SRS, the 2 most frequent molecular abnormalities ar …
INTRODUCTION: Silver-Russell syndrome (SRS) is characterized by clinical and genetic heterogeneity. SRS is the only disease entity as …
The Effects of a Remote-based Weight Loss Program on Adipocytokines, Metabolic Markers, and Telomere Length in Breast Cancer Survivors: the POWER-Remote Trial.
Santa-Maria CA, Coughlin JW, Sharma D, Armanios M, Blackford AL, Schreyer C, Dalcin A, Carpenter A, Jerome GJ, Armstrong DK, Chaudhry M, Cohen GI, Connolly RM, Fetting J, Miller RS, Smith KL, Snyder C, Wolfe A, Wolff AC, Huang CY, Appel LJ, Stearns V. Santa-Maria CA, et al. Clin Cancer Res. 2020 Jun 15;26(12):3024-3034. doi: 10.1158/1078-0432.CCR-19-2935. Epub 2020 Feb 18. Clin Cancer Res. 2020. PMID: 32071117 Free PMC article. Clinical Trial.
PURPOSE: We initiated a clinical trial to determine the proportion of breast cancer survivors achieving 5% weight loss using a remotely delivered weight loss intervention (POWER-remote) or a self-directed approach, and to determine the effects of the i …
PURPOSE: We initiated a clinical trial to determine the proportion of breast cancer survivors achieving 5% weight loss …
Lack of association between denture trauma and loss of heterozygosity confronts the proposed pathologic role of chronic mucosal trauma in oral carcinogenesis.
Bernardes VF, Diniz MG, Silva JC, Moraes DC, De Marco L, Gomes CC, Gomez RS. Bernardes VF, et al. J Oral Pathol Med. 2019 May;48(5):421-423. doi: 10.1111/jop.12846. Epub 2019 Mar 21. J Oral Pathol Med. 2019. PMID: 30849196
If chronic trauma of the oral mucosa is carcinogenic, it should be associated with early genetic alterations seen during typical progression of OSCC, like loss of heterozygosity (LOH). We investigated LOH in the key chromosomal arms 3p, 9p and 17p in inflamma …
If chronic trauma of the oral mucosa is carcinogenic, it should be associated with early genetic alterations seen during typical progression …
Patterns of allelic loss differ in lung adenocarcinomas of smokers and nonsmokers.
Powell CA, Bueno R, Borczuk AC, Caracta CF, Richards WG, Sugarbaker DJ, Brody JS. Powell CA, et al. Lung Cancer. 2003 Jan;39(1):23-9. doi: 10.1016/s0169-5002(02)00384-7. Lung Cancer. 2003. PMID: 12499090
The extent of allelic loss in smokers, as measured by fractional allelic loss (FAL), was compared with nonsmokers. LOH was more frequent in the tumors of nonsmokers than of smokers with mean FAL of 46% in nonsmokers and 28% in smokers (P<0.05). Increased LOH in n …
The extent of allelic loss in smokers, as measured by fractional allelic loss (FAL), was compared with nonsmokers. LOH was mor …
Genome-wide analysis of Ollier disease: Is it all in the genes?
Pansuriya TC, Oosting J, Krenács T, Taminiau AH, Verdegaal SH, Sangiorgi L, Sciot R, Hogendoorn PC, Szuhai K, Bovée JV. Pansuriya TC, et al. Orphanet J Rare Dis. 2011 Jan 14;6:2. doi: 10.1186/1750-1172-6-2. Orphanet J Rare Dis. 2011. PMID: 21235737 Free PMC article.
RESULTS: Non-recurrent EC specific copy number alterations were found at FAM86D, PRKG1 and ANKS1B. LOH with copy number loss of chromosome 6 was found in two ECs from two unrelated Ollier patients. ...None of these candidate regions were affected in more than two Ol …
RESULTS: Non-recurrent EC specific copy number alterations were found at FAM86D, PRKG1 and ANKS1B. LOH with copy number loss of ch …
Cytogenetics of primary prostatic adenocarcinoma. Clonality and chromosome instability.
Micale MA, Mohamed A, Sakr W, Powell IJ, Wolman SR. Micale MA, et al. Cancer Genet Cytogenet. 1992 Jul 15;61(2):165-73. doi: 10.1016/0165-4608(92)90082-j. Cancer Genet Cytogenet. 1992. PMID: 1638499
The most consistent finding was a normal male diploid karyotype, found in 87% of all cells analyzed, and as the exclusive finding in 19 tumors. Nonrandom chromosomal changes included gain of chromosome 7 and loss of the Y chromosome. ...In those cases …
The most consistent finding was a normal male diploid karyotype, found in 87% of all cells analyzed, and as the exclusive finding in 19 tumo …
90 results