Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 3
1971 2
1972 2
1973 4
1974 7
1975 12
1976 21
1977 16
1978 10
1979 8
1980 11
1981 13
1982 20
1983 11
1984 14
1985 3
1986 6
1987 4
1988 8
1989 9
1990 6
1991 8
1992 8
1993 14
1994 8
1995 9
1996 12
1997 10
1998 8
1999 19
2000 7
2001 8
2002 3
2003 13
2004 4
2005 7
2006 12
2007 11
2008 3
2009 7
2010 12
2011 21
2012 16
2013 15
2014 13
2015 16
2016 19
2017 28
2018 11
2019 15
2020 9
2021 21
2022 15
2023 13
2024 10

Text availability

Article attribute

Article type

Publication date

Search Results

558 results

Results by year

Filters applied: . Clear all
Page 1
Loxapine.
[No authors listed] [No authors listed] 2021 Jan 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Jan 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000069 Free Books & Documents. Review.
Because no information is available on the use of loxapine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant....
Because no information is available on the use of loxapine during breastfeeding, an alternate drug may be preferred, especially while …
Loxapine.
[No authors listed] [No authors listed] 2022 Nov. Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994–. 2022 Nov. Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994–. PMID: 35952080 Free Books & Documents. Review.
This sheet is about exposure to loxapine in pregnancy and while breastfeeding. This information should not take the place of medical care and advice from your healthcare provider....
This sheet is about exposure to loxapine in pregnancy and while breastfeeding. This information should not take the place of medical …
Loxapine.
[No authors listed] [No authors listed] 2019 May 21. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2019 May 21. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31644182 Free Books & Documents. Review.
Loxapine is a conventional antipsychotic used in the therapy of schizophrenia. Loxapine therapy is commonly associated with minor serum aminotransferase elevations and in very rare instances has been linked to clinically apparent acute liver injury....
Loxapine is a conventional antipsychotic used in the therapy of schizophrenia. Loxapine therapy is commonly associated with mi
Loxapine for schizophrenia.
Chakrabarti A, Bagnall A, Chue P, Fenton M, Palaniswamy V, Wong W, Xia J. Chakrabarti A, et al. Cochrane Database Syst Rev. 2007 Oct 17;2007(4):CD001943. doi: 10.1002/14651858.CD001943.pub2. Cochrane Database Syst Rev. 2007. PMID: 17943763 Free PMC article. Review.
Very limited heterogeneous data suggest that, given intramuscularly (IM), loxapine may be at least as sedating as IM haloperidol and thiothixene. Loxapine is also as effective as atypicals (risperidone, quetiapine) (n=468, 6 RCTs, RR mental state not improved 1.07 C …
Very limited heterogeneous data suggest that, given intramuscularly (IM), loxapine may be at least as sedating as IM haloperidol and …
Loxapine update: 1966-1976.
Ayd FJ Jr. Ayd FJ Jr. Dis Nerv Syst. 1977 Nov;38(11):883-7. Dis Nerv Syst. 1977. PMID: 410614 Review. No abstract available.
Loxapine for schizophrenia.
Fenton M, Murphy B, Wood J, Bagnall A, Chue P, Leitner M. Fenton M, et al. Cochrane Database Syst Rev. 2000;(2):CD001943. doi: 10.1002/14651858.CD001943. Cochrane Database Syst Rev. 2000. PMID: 10796455 Updated. Review.
BACKGROUND: Loxapine is a drug with D2/D3 receptor antagonist activity and a higher affinity for D3 than D2. ...Very limited heterogeneous data suggest that, given intramuscularly (IM), loxapine may be at least as sedating as IM haloperidol and thiothixene. ...
BACKGROUND: Loxapine is a drug with D2/D3 receptor antagonist activity and a higher affinity for D3 than D2. ...Very limited heteroge …
Fifty years of experience with loxapine for the rapid non-coercive tranquilization of acute behavioral disturbances in schizophrenia patients, and beyond.
Nuss P, Corruble E, Baloche E, P Garay R, Llorca PM. Nuss P, et al. Expert Rev Neurother. 2022 Aug;22(8):639-653. doi: 10.1080/14737175.2022.2108706. Epub 2022 Aug 10. Expert Rev Neurother. 2022. PMID: 35913401 Review.
Furthermore, animal pharmacology and clinical studies on agitation reveal the robust calming and anxiolytic properties of loxapine. AREAS COVERED: This review covers the pharmacological and clinical history of loxapine along with research developments. ...Loxapin
Furthermore, animal pharmacology and clinical studies on agitation reveal the robust calming and anxiolytic properties of loxapine. A …
Loxapine in patient with clozapine-resistant psychosis.
Erley J, Goldsborough S, VandenBerg A, Audu A. Erley J, et al. Ment Health Clin. 2021 Jul 16;11(4):263-266. doi: 10.9740/mhc.2021.07.263. eCollection 2021 Jul. Ment Health Clin. 2021. PMID: 34316424 Free PMC article.
Clozapine is recognized as the drug of choice for treatment-refractory schizophrenia, but use may be limited because of strict monitoring requirements and adverse effects including severe neutropenia, seizures, and myocarditis. Loxapine is a first-generation antipsychotic …
Clozapine is recognized as the drug of choice for treatment-refractory schizophrenia, but use may be limited because of strict monitoring re …
Loxapine inhalation powder: a review of its use in the acute treatment of agitation in patients with bipolar disorder or schizophrenia.
Keating GM. Keating GM. CNS Drugs. 2013 Jun;27(6):479-89. doi: 10.1007/s40263-013-0075-9. CNS Drugs. 2013. PMID: 23740380 Review.
Loxapine is a well-established, first-generation antipsychotic agent. ...Inhaled loxapine is delivered by a hand-held, single-dose, single-use device that uses the Staccato() drug delivery system. ...
Loxapine is a well-established, first-generation antipsychotic agent. ...Inhaled loxapine is delivered by a hand-held, single-
Inhaled Loxapine for the Management of Acute Agitation in Bipolar Disorder and Schizophrenia: Expert Review and Commentary in an Era of Change.
Pacciardi B, Calcedo A, Messer T. Pacciardi B, et al. Drugs R D. 2019 Mar;19(1):15-25. doi: 10.1007/s40268-019-0262-3. Drugs R D. 2019. PMID: 30721526 Free PMC article. Review.
Rapid symptom relief and de-escalation of agitation are necessary to avoid the costly and traumatic use of coercive techniques of physical restraint and seclusion, which require admission and prolonged hospitalisation. Inhaled loxapine is approved for the treatment of acut …
Rapid symptom relief and de-escalation of agitation are necessary to avoid the costly and traumatic use of coercive techniques of physical r …
558 results