Smoking-associated Downregulation of FILIP1L Enhances Lung Adenocarcinoma Progression Through Mucin Production, Inflammation, and Fibrosis.
Kwon M, Rubio G, Wang H, Riedlinger G, Adem A, Zhong H, Slegowski D, Post-Zwicker L, Chidananda A, Schrump DS, Pine SR, Libutti SK.
Kwon M, et al.
Cancer Res Commun. 2022 Oct 18;2(10):1197-1213. doi: 10.1158/2767-9764.CRC-22-0233. eCollection 2022 Oct.
Cancer Res Commun. 2022.
PMID: 36860703
Free PMC article.
SIGNIFICANCE: This study identifies FILIP1L as a tumor suppressor in LUADs and demonstrates that downregulation of FILIP1L is a clinically relevant event in the pathogenesis and clinical course of these neoplasms....
SIGNIFICANCE: This study identifies FILIP1L as a tumor suppressor in LUADs and demonstrates that downregulation of FILIP1L is a clinically r …