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Treatment of Childhood-Onset Lupus Erythematosus Panniculitis With Rituximab.
Correll CK, Miller DD, Maguiness SM. Correll CK, et al. JAMA Dermatol. 2020 May 1;156(5):566-569. doi: 10.1001/jamadermatol.2019.4984. JAMA Dermatol. 2020. PMID: 32049306 Free PMC article.
IMPORTANCE: Childhood-onset lupus erythematosus panniculitis (LEP) is a rare and chronic disfiguring disease. ...OBJECTIVES: To describe the clinical features of childhood-onset LEP and report on the use of rituximab in treatment-refractory childhood-onset LE …
IMPORTANCE: Childhood-onset lupus erythematosus panniculitis (LEP) is a rare and chronic disfiguring disease. ...OBJECT …
Panniculitis in childhood-onset systemic lupus erythematosus: a multicentric cohort study.
Verdier M, Anuardo P, Gormezano NWS, Romiti R, Campos LMA, Aikawa NE, Pereira RMR, Terreri MT, Magalhães CS, Ferreira JCOA, Silva MFC, Ferriani M, Sakamoto AP, Ferriani VPL, Centeville M, Sato J, Santos MC, Bonfá E, Silva CA. Verdier M, et al. Adv Rheumatol. 2019 Jan 18;59(1):3. doi: 10.1186/s42358-019-0049-9. Adv Rheumatol. 2019. PMID: 30658703

Statistical analysis was performed using Bonferroni correction(p < 0.004). RESULTS: Panniculitis was observed in 6/847(0.7%) cSLE. Painful subcutaneous erythematosus and indurated nodules were observed in 6/6 panniculitis patients and painful subcutaneous plaques

Statistical analysis was performed using Bonferroni correction(p < 0.004). RESULTS: Panniculitis was observed in 6/847(0.7%) cSLE.

Subcutaneous panniculitis-like T-cell lymphoma, lupus erythematosus profundus, and overlapping cases: molecular characterization through the study of 208 genes.
Machan S, Rodríguez M, Alonso-Alonso R, Manso R, Pérez-Buira S, Borregón J, Rodríguez-Peralto JL, Cerroni L, Haro R, García C, García Toro E, Estrach T, García-Herrera A, Ferrer B, González-Cruz C, Segues N, Afonso-Martin JL, Peñate Y, Monteagudo C, Limeres-Gonzalez MÁ, González-Núñez MÁ, Torres MÁT, Cereceda L, Córdoba R, Piris MÁ, Requena L, María Rodríguez-Pinilla S. Machan S, et al. Leuk Lymphoma. 2021 Sep;62(9):2130-2140. doi: 10.1080/10428194.2021.1901098. Epub 2021 May 8. Leuk Lymphoma. 2021. PMID: 33966586
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare cytotoxic cutaneous lymphoma. Differential diagnosis with lupus erythematosus panniculitis (LEP) can be challenging and overlapping cases have been described. ...Most overlapping cases were clus …
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare cytotoxic cutaneous lymphoma. Differential diagnosis with lupus e
Panniculitis: recent developments and observations.
White WL, Wieselthier JS, Hitchcock MG. White WL, et al. Semin Cutan Med Surg. 1996 Dec;15(4):278-99. doi: 10.1016/s1085-5629(96)80042-3. Semin Cutan Med Surg. 1996. PMID: 9069596 Review.
Lupus erythematosus panniculitis in children and adolescents.
Guissa VR, Trudes G, Jesus AA, Aikawa NE, Romiti R, Silva CA. Guissa VR, et al. Acta Reumatol Port. 2012 Jan-Mar;37(1):82-5. Acta Reumatol Port. 2012. PMID: 22781517 Free article.
INTRODUCTION: Lupus erythematosus panniculitis (LEP) or lupus erythematosus profundus is a rare form of chronic cutaneous manifestation affecting both adults and pediatric patients. ...However, skin lesions improved only after rituximab treatment. DISCUSSION: …
INTRODUCTION: Lupus erythematosus panniculitis (LEP) or lupus erythematosus profundus is a rare form of chronic cutaneo …
IRF8 in Conjunction With CD123 and CD20 to Distinguish Lupus Erythematosus Panniculitis From Subcutaneous Panniculitis-like T-Cell Lymphoma.
Wong J, Roy SF, McNiff JM, Xu ML. Wong J, et al. Am J Surg Pathol. 2023 Dec 1;47(12):1425-1431. doi: 10.1097/PAS.0000000000002133. Epub 2023 Sep 28. Am J Surg Pathol. 2023. PMID: 37767989
Distinguishing lupus erythematosus panniculitis (LEP) from subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a diagnostic challenge with important clinical implications. ...We found that clusters of IRF8-positive cells within the dermis, and away from …
Distinguishing lupus erythematosus panniculitis (LEP) from subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a …
Eosinophils in lupus panniculitis and morphea profunda.
Peters MS, Su WP. Peters MS, et al. J Cutan Pathol. 1991 Jun;18(3):189-92. doi: 10.1111/j.1600-0560.1991.tb00151.x. J Cutan Pathol. 1991. PMID: 1918506
However, in most of the specimens, eosinophils were absent or observed in small numbers. Only 3% of patients with lupus panniculitis showed an increase in the number of eosinophils in the peripheral blood, whereas 47% of patients with morphea profunda had peripheral eosino …
However, in most of the specimens, eosinophils were absent or observed in small numbers. Only 3% of patients with lupus panniculitis …
Utility of CD123 immunohistochemistry in differentiating lupus erythematosus from cutaneous T cell lymphoma.
Chen SJT, Tse JY, Harms PW, Hristov AC, Chan MP. Chen SJT, et al. Histopathology. 2019 May;74(6):908-916. doi: 10.1111/his.13817. Epub 2019 Mar 20. Histopathology. 2019. PMID: 30597607 Free article.
METHODS AND RESULTS: Skin biopsies of cutaneous lupus erythematosus (CLE, n = 18), lupus erythematosus panniculitis (LEP, n = 17), mycosis fungoides (MF, n = 25) and subcutaneous panniculitis-like T cell lymphoma (SPTCL, n = 9) were retrospectively reviewed a …
METHODS AND RESULTS: Skin biopsies of cutaneous lupus erythematosus (CLE, n = 18), lupus erythematosus panniculitis (LE …
Lupus erythematosus panniculitis in a 10-year-old female child with severe systemic lupus erythematosus: A case report.
Zhang R, Dang X, Shuai L, He Q, He X, Yi Z. Zhang R, et al. Medicine (Baltimore). 2018 Jan;97(3):e9571. doi: 10.1097/MD.0000000000009571. Medicine (Baltimore). 2018. PMID: 29504978 Free PMC article.
RATIONALE: Lupus erythematosus panniculitis (LEP) is a rare subset of lupus erythematosus. ...PATIENT CONCERNS: A 10-year-old girl was admitted to our hospital for marasmus and fatigue without other typical manifestations of SLE well before the appearance of …
RATIONALE: Lupus erythematosus panniculitis (LEP) is a rare subset of lupus erythematosus. ...PATIENT CONCERNS: A 10-ye …
The natural history of pediatric-onset discoid lupus erythematosus.
Arkin LM, Ansell L, Rademaker A, Curran ML, Miller ML, Wagner A, Kenner-Bell BM, Chamlin SL, Mancini AJ, Klein-Gitelman M, Paller AS. Arkin LM, et al. J Am Acad Dermatol. 2015 Apr;72(4):628-33. doi: 10.1016/j.jaad.2014.12.028. Epub 2015 Jan 30. J Am Acad Dermatol. 2015. PMID: 25648823
CONCLUSIONS: In pediatric patients, DLE carries a significant risk of progression to SLE but may predict a milder phenotype of systemic disease. All patients require careful monitoring for SLE, particularly within the first year of diagnosis....
CONCLUSIONS: In pediatric patients, DLE carries a significant risk of progression to SLE but may predict a milder phenotype of system …
32 results