Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1989 2
1990 2
1991 1
1992 2
1993 5
1994 1
1995 5
1996 2
1998 1
1999 3
2000 1
2001 1
2003 3
2004 2
2005 6
2006 11
2007 15
2008 23
2009 36
2010 45
2011 54
2012 57
2013 72
2014 62
2015 85
2016 65
2017 83
2018 85
2019 77
2020 99
2021 87
2022 75
2023 53
2024 25

Text availability

Article attribute

Article type

Publication date

Search Results

965 results

Results by year

Filters applied: . Clear all
Page 1
Identification of Lynch Syndrome.
Maratt JK, Stoffel E. Maratt JK, et al. Gastrointest Endosc Clin N Am. 2022 Jan;32(1):45-58. doi: 10.1016/j.giec.2021.09.002. Gastrointest Endosc Clin N Am. 2022. PMID: 34798986 Review.
Individuals at risk for LS can be identified by using clinical criteria, prediction models, and universal tumor testing. Understanding each of these tools, including limitations and mimics of LS, is essential to the early identification of at-risk individuals....
Individuals at risk for LS can be identified by using clinical criteria, prediction models, and universal tumor testing. Understandin …
Mismatch repair deficiency: The what, how and why it is important.
Olave MC, Graham RP. Olave MC, et al. Genes Chromosomes Cancer. 2022 Jun;61(6):314-321. doi: 10.1002/gcc.23015. Epub 2021 Dec 9. Genes Chromosomes Cancer. 2022. PMID: 34837268 Review.
Detection of deficient mismatch repair function or microsatellite instability is used diagnostically, predictively, and prognostically. Specifically, deficient mismatch repair function is used for screening of Lynch syndrome, determining patients who are likely to r …
Detection of deficient mismatch repair function or microsatellite instability is used diagnostically, predictively, and prognostic …
Microsatellite instability in colorectal cancer.
De' Angelis GL, Bottarelli L, Azzoni C, De' Angelis N, Leandro G, Di Mario F, Gaiani F, Negri F. De' Angelis GL, et al. Acta Biomed. 2018 Dec 17;89(9-S):97-101. doi: 10.23750/abm.v89i9-S.7960. Acta Biomed. 2018. PMID: 30561401 Free PMC article. Review.
Identification of MSI CRC is important, as MSI may serve as a screening tool for detecting LS, a prognostic marker for patient outcome, and a predictive marker for response to chemotherapy and to immunotherapy....
Identification of MSI CRC is important, as MSI may serve as a screening tool for detecting LS, a prognostic marker for patient outcom …
Mucinous colorectal adenocarcinoma: clinical pathology and treatment options.
Luo C, Cen S, Ding G, Wu W. Luo C, et al. Cancer Commun (Lond). 2019 Mar 29;39(1):13. doi: 10.1186/s40880-019-0361-0. Cancer Commun (Lond). 2019. PMID: 30922401 Free PMC article. Review.
Mucinous colorectal adenocarcinoma also shows higher rates of microsatellite instability (MSI) than non-mucinous colorectal adenocarcinoma which might correlate it with Lynch syndrome and the CpG island methylator phenotype. The prognosis of mucinous colorectal adenocarcin …
Mucinous colorectal adenocarcinoma also shows higher rates of microsatellite instability (MSI) than non-mucinous colorectal adenocarcinoma w …
The evolving role of microsatellite instability in colorectal cancer: A review.
Gelsomino F, Barbolini M, Spallanzani A, Pugliese G, Cascinu S. Gelsomino F, et al. Cancer Treat Rev. 2016 Dec;51:19-26. doi: 10.1016/j.ctrv.2016.10.005. Epub 2016 Oct 27. Cancer Treat Rev. 2016. PMID: 27838401 Free article. Review.
In early-stage CRC, MSI can select a group of tumors with a better prognosis, while in metastatic disease it seems to confer a negative prognosis. ...
In early-stage CRC, MSI can select a group of tumors with a better prognosis, while in metastatic disease it seems to confer a negati …
Update in the molecular classification of endometrial carcinoma.
Léon-Castillo A. Léon-Castillo A. Int J Gynecol Cancer. 2023 Mar 6;33(3):333-342. doi: 10.1136/ijgc-2022-003772. Int J Gynecol Cancer. 2023. PMID: 36878561 Review.
In the last decade, several studies have reported the strong prognostic value of the molecular endometrial carcinoma subgroups and, more recently, its potential to inform adjuvant treatment decisions. ...
In the last decade, several studies have reported the strong prognostic value of the molecular endometrial carcinoma subgroups and, m …
Methylation Tolerance-Based Functional Assay to Assess Variants of Unknown Significance in the MLH1 and MSH2 Genes and Identify Patients With Lynch Syndrome.
Bouvet D, Bodo S, Munier A, Guillerm E, Bertrand R, Colas C, Duval A, Coulet F, Muleris M. Bouvet D, et al. Gastroenterology. 2019 Aug;157(2):421-431. doi: 10.1053/j.gastro.2019.03.071. Epub 2019 Apr 15. Gastroenterology. 2019. PMID: 30998989
Using this assay, we analyzed 88 variants (mainly missense variants), comprising a validation set of 40 previously classified variants (19 in MLH1 and 21 in MSH2) and a prospective set of 48 VUS (25 in MLH1 and 23 in MSH2). Prediction scores were calculated for all VUS acc …
Using this assay, we analyzed 88 variants (mainly missense variants), comprising a validation set of 40 previously classified variants (19 i …
Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial.
Burn J, Sheth H, Elliott F, Reed L, Macrae F, Mecklin JP, Möslein G, McRonald FE, Bertario L, Evans DG, Gerdes AM, Ho JWC, Lindblom A, Morrison PJ, Rashbass J, Ramesar R, Seppälä T, Thomas HJW, Pylvänäinen K, Borthwick GM, Mathers JC, Bishop DT; CAPP2 Investigators. Burn J, et al. Lancet. 2020 Jun 13;395(10240):1855-1863. doi: 10.1016/S0140-6736(20)30366-4. Lancet. 2020. PMID: 32534647 Free PMC article. Clinical Trial.
MSI/MMR-deficient tumor diagnosis: Which standard for screening and for diagnosis? Diagnostic modalities for the colon and other sites: Differences between tumors.
Svrcek M, Lascols O, Cohen R, Collura A, Jonchère V, Fléjou JF, Buhard O, Duval A. Svrcek M, et al. Bull Cancer. 2019 Feb;106(2):119-128. doi: 10.1016/j.bulcan.2018.12.008. Epub 2019 Feb 1. Bull Cancer. 2019. PMID: 30713006 Free article. Review.
Moreover, research has recently focused increasingly on MMR deficiency due to its positive predictive value for the efficacy of immune checkpoints inhibitors (ICKi) in metastatic tumors, regardless of their primary origin. MSI has also been demonstrated to constitute an in …
Moreover, research has recently focused increasingly on MMR deficiency due to its positive predictive value for the efficacy of immun …
965 results