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1993 1
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1999 1
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2008 1
2010 3
2011 1
2012 1
2014 3
2015 1
2016 4
2017 6
2018 9
2019 5
2020 9
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2024 1

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66 results

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Quoted phrase not found in phrase index: "MET NP_000236.2:p.M1250T"
Page 1
Tracking the Evolution of Non-Small-Cell Lung Cancer.
Jamal-Hanjani M, Wilson GA, McGranahan N, Birkbak NJ, Watkins TBK, Veeriah S, Shafi S, Johnson DH, Mitter R, Rosenthal R, Salm M, Horswell S, Escudero M, Matthews N, Rowan A, Chambers T, Moore DA, Turajlic S, Xu H, Lee SM, Forster MD, Ahmad T, Hiley CT, Abbosh C, Falzon M, Borg E, Marafioti T, Lawrence D, Hayward M, Kolvekar S, Panagiotopoulos N, Janes SM, Thakrar R, Ahmed A, Blackhall F, Summers Y, Shah R, Joseph L, Quinn AM, Crosbie PA, Naidu B, Middleton G, Langman G, Trotter S, Nicolson M, Remmen H, Kerr K, Chetty M, Gomersall L, Fennell DA, Nakas A, Rathinam S, Anand G, Khan S, Russell P, Ezhil V, Ismail B, Irvin-Sellers M, Prakash V, Lester JF, Kornaszewska M, Attanoos R, Adams H, Davies H, Dentro S, Taniere P, O'Sullivan B, Lowe HL, Hartley JA, Iles N, Bell H, Ngai Y, Shaw JA, Herrero J, Szallasi Z, Schwarz RF, Stewart A, Quezada SA, Le Quesne J, Van Loo P, Dive C, Hackshaw A, Swanton C; TRACERx Consortium. Jamal-Hanjani M, et al. N Engl J Med. 2017 Jun 1;376(22):2109-2121. doi: 10.1056/NEJMoa1616288. Epub 2017 Apr 26. N Engl J Med. 2017. PMID: 28445112 Free article.
RESULTS: We observed widespread intratumor heterogeneity for both somatic copy-number alterations and mutations. Driver mutations in EGFR, MET, BRAF, and TP53 were almost always clonal. However, heterogeneous driver alterations that occurred later in evolution were found i …
RESULTS: We observed widespread intratumor heterogeneity for both somatic copy-number alterations and mutations. Driver mutations in EGFR, …
Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit.
Gaudry S, Hajage D, Schortgen F, Martin-Lefevre L, Pons B, Boulet E, Boyer A, Chevrel G, Lerolle N, Carpentier D, de Prost N, Lautrette A, Bretagnol A, Mayaux J, Nseir S, Megarbane B, Thirion M, Forel JM, Maizel J, Yonis H, Markowicz P, Thiery G, Tubach F, Ricard JD, Dreyfuss D; AKIKI Study Group. Gaudry S, et al. N Engl J Med. 2016 Jul 14;375(2):122-33. doi: 10.1056/NEJMoa1603017. Epub 2016 May 15. N Engl J Med. 2016. PMID: 27181456 Free article. Clinical Trial.
With the delayed strategy, renal-replacement therapy was initiated if at least one of the following criteria was met: severe hyperkalemia, metabolic acidosis, pulmonary edema, blood urea nitrogen level higher than 112 mg per deciliter, or oliguria for more than 72 hours af …
With the delayed strategy, renal-replacement therapy was initiated if at least one of the following criteria was met: severe hyperkal …
Epidemiology of Shock in Contemporary Cardiac Intensive Care Units.
Berg DD, Bohula EA, van Diepen S, Katz JN, Alviar CL, Baird-Zars VM, Barnett CF, Barsness GW, Burke JA, Cremer PC, Cruz J, Daniels LB, DeFilippis AP, Haleem A, Hollenberg SM, Horowitz JM, Keller N, Kontos MC, Lawler PR, Menon V, Metkus TS, Ng J, Orgel R, Overgaard CB, Park JG, Phreaner N, Roswell RO, Schulman SP, Jeffrey Snell R, Solomon MA, Ternus B, Tymchak W, Vikram F, Morrow DA. Berg DD, et al. Circ Cardiovasc Qual Outcomes. 2019 Mar;12(3):e005618. doi: 10.1161/CIRCOUTCOMES.119.005618. Circ Cardiovasc Qual Outcomes. 2019. PMID: 30879324 Free PMC article.
Shock type was classified by site investigators as cardiogenic, distributive, hypovolemic, or mixed. Among 3049 CICU admissions, 677 (22%) met clinical criteria for shock. Shock type was varied, with 66% assessed as cardiogenic shock (CS), 7% as distributive, 3% as hypovol …
Shock type was classified by site investigators as cardiogenic, distributive, hypovolemic, or mixed. Among 3049 CICU admissions, 677 (22%) …
Sex-specific disease modifiers in juvenile myoclonic epilepsy.
Shakeshaft A, Panjwani N, Collingwood A, Crudgington H, Hall A, Andrade DM, Beier CP, Fong CY, Gardella E, Gesche J, Greenberg DA, Hamandi K, Koht J, Lim KS, Møller RS, Ng CC, Orsini A, Rees MI, Rubboli G, Selmer KK, Striano P, Syvertsen M, Thomas RH, Zarubova J, Richardson MP, Strug LJ, Pal DK. Shakeshaft A, et al. Sci Rep. 2022 Feb 21;12(1):2785. doi: 10.1038/s41598-022-06324-2. Sci Rep. 2022. PMID: 35190554 Free PMC article.
Juvenile myoclonic epilepsy (JME) is a common idiopathic generalised epilepsy with variable seizure prognosis and sex differences in disease presentation. Here, we investigate the combined epidemiology of sex, seizure types and precipitants, and their influence on progn …
Juvenile myoclonic epilepsy (JME) is a common idiopathic generalised epilepsy with variable seizure prognosis and sex differences in …
Proteinuria in Dent disease: a review of the literature.
van Berkel Y, Ludwig M, van Wijk JAE, Bökenkamp A. van Berkel Y, et al. Pediatr Nephrol. 2017 Oct;32(10):1851-1859. doi: 10.1007/s00467-016-3499-x. Epub 2016 Oct 18. Pediatr Nephrol. 2017. PMID: 27757584 Free PMC article. Review.
Fifty-five of 126 (43.7 %) Dent-1 vs 13/22 (59.1 %) Dent-2 patients met the definition of NP (p = 0.25). Serum albumin was normal in all reported cases (24/148). ...Even with normal renal function, glomerulosclerosis and tubulointerstitial fibrosis are present in Dent dise …
Fifty-five of 126 (43.7 %) Dent-1 vs 13/22 (59.1 %) Dent-2 patients met the definition of NP (p = 0.25). Serum albumin was normal in …
Left Ventricular Systolic Dysfunction in Patients Diagnosed With Hypertrophic Cardiomyopathy During Childhood: Insights From the SHaRe Registry.
Abou Alaiwi S, Roston TM, Marstrand P, Claggett BL, Parikh VN, Helms AS, Ingles J, Lampert R, Lakdawala NK, Michels M, Owens AT, Rossano JW, Saberi S, Abrams DJ, Ashley EA, Semsarian C, Stendahl JC, Ware JS, Miller E, Ryan TD, Russell MW, Day SM, Olivotto I, Vissing CR, Ho CY. Abou Alaiwi S, et al. Circulation. 2023 Aug;148(5):394-404. doi: 10.1161/CIRCULATIONAHA.122.062517. Epub 2023 May 25. Circulation. 2023. PMID: 37226762 Free PMC article.
BACKGROUND: The development of left ventricular systolic dysfunction (LVSD) in hypertrophic cardiomyopathy (HCM) is rare but serious and associated with poor outcomes in adults. Little is known about the prevalence, predictors, and prognosis of LVSD in patients diag …
BACKGROUND: The development of left ventricular systolic dysfunction (LVSD) in hypertrophic cardiomyopathy (HCM) is rare but serious and ass …
Gynecological cancer prognosis using machine learning techniques: A systematic review of the last three decades (1990-2022).
Sheehy J, Rutledge H, Acharya UR, Loh HW, Gururajan R, Tao X, Zhou X, Li Y, Gurney T, Kondalsamy-Chennakesavan S. Sheehy J, et al. Artif Intell Med. 2023 May;139:102536. doi: 10.1016/j.artmed.2023.102536. Epub 2023 Mar 29. Artif Intell Med. 2023. PMID: 37100507 Review.
The objective of this systematic review was to assess and critically appraise the methodologies and approaches used in predicting the prognosis of gynecological cancers using CAPs. METHODS: Electronic databases were used to systematically search for studies utilizin …
The objective of this systematic review was to assess and critically appraise the methodologies and approaches used in predicting the …
Teaching Diagnostic Reasoning: A Review of Evidence-Based Interventions.
Burt L, Corbridge S. Burt L, et al. Int J Nurs Educ Scholarsh. 2018 Nov 2;15(1):/j/ijnes.2018.15.issue-1/ijnes-2018-0003/ijnes-2018-0003.xml. doi: 10.1515/ijnes-2018-0003. Int J Nurs Educ Scholarsh. 2018. PMID: 30388079 Review.
METHODS: An integrative literature review was conducted in order to identify original research focusing on diagnostic reasoning educational interventions. RESULTS: Eighteen primary sources met inclusion and exclusion criteria. Results are synthesized in terms of sample and …
METHODS: An integrative literature review was conducted in order to identify original research focusing on diagnostic reasoning educational …
The prognostic role of p53 mutations in metastatic colorectal cancer: A systematic review and meta-analysis.
Ottaiano A, Santorsola M, Capuozzo M, Perri F, Circelli L, Cascella M, Ianniello M, Sabbatino F, Granata V, Izzo F, Iervolino D, Casillo M, Petrillo N, Gualillo O, Nasti G, Savarese G. Ottaiano A, et al. Crit Rev Oncol Hematol. 2023 Jun;186:104018. doi: 10.1016/j.critrevonc.2023.104018. Epub 2023 May 5. Crit Rev Oncol Hematol. 2023. PMID: 37150312 Free article. Review.
The relationship between p53 mutation and clinic-pathological variables was examined using the chi(2) test. RESULTS: Nine articles met the eligibility criteria and went to the final analysis. Sample size ranged from 51 to 1043 patients. ...The final pooled HR (p53 mutated …
The relationship between p53 mutation and clinic-pathological variables was examined using the chi(2) test. RESULTS: Nine articles met …
Which neoadjuvant chemotherapy regimen should be recommended for patients with advanced nasopharyngeal carcinoma?: A network meta-analysis.
Yuan C, Xu XH, Luo SW, Wang L, Sun M, Ni LH, Xu L, Wang XL, Zeng G. Yuan C, et al. Medicine (Baltimore). 2018 Aug;97(34):e11978. doi: 10.1097/MD.0000000000011978. Medicine (Baltimore). 2018. PMID: 30142830 Free PMC article. Review.
METHODS: A systematic literature search was performed using PubMed, Embase, and Cochran Library. Totally, 31 randomized controlled trials (RCTs) (n = 4062) met study selection criteria and were incorporated in this NMA study. ...CONCLUSION: Our NMA showed that certain cisp …
METHODS: A systematic literature search was performed using PubMed, Embase, and Cochran Library. Totally, 31 randomized controlled trials (R …
66 results