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ARMC5-negative primary bilateral macronodular adrenal hyperplasia.
Sol B, Carprieaux M, De Leu N. Sol B, et al. BMJ Case Rep. 2023 Jul 6;16(7):e254099. doi: 10.1136/bcr-2022-254099. BMJ Case Rep. 2023. PMID: 37419498
Abdominal imaging showed bilateral macronodular adrenals, measuring 58.9 29.7 mm on the right and 55.6 42.6 mm on the left. Primary bilateral macronodular adrenal hyperplasia was confirmed by pathology after bilateral adrenalectomy. ...Primary bilateral ma …
Abdominal imaging showed bilateral macronodular adrenals, measuring 58.9 29.7 mm on the right and 55.6 42.6 mm on the left. Primary bilatera …
Prevalence and clinical features of armadillo repeat-containing 5 mutations carriers in a single center cohort of patients with bilateral adrenal incidentalomas.
Morelli V, Elli FM, Frigerio S, Vena W, Palmieri S, Lucca C, Maffini MA, Contarino A, Bagnaresi F, Mantovani G, Arosio M. Morelli V, et al. Eur J Endocrinol. 2023 Aug 2;189(2):242-251. doi: 10.1093/ejendo/lvad088. Eur J Endocrinol. 2023. PMID: 37625448
Moreover, somatic ARMC5 pathogenic variants were also found in the adrenal tissue of six patients without germline ARMC5 variants. The F-1mgDST levels >5 g/dL predicted with a poor sensitivity but a 90.5% specificity in identifying the presence of ARMC5 germline pathoge …
Moreover, somatic ARMC5 pathogenic variants were also found in the adrenal tissue of six patients without germline ARMC5 variants. The F-1mg …
MicroRNA expression signature and target prediction in familial and sporadic primary macronodular adrenal hyperplasia (PMAH).
Tan XG, Zhu J, Cui L. Tan XG, et al. BMC Endocr Disord. 2022 Jan 5;22(1):11. doi: 10.1186/s12902-021-00910-7. BMC Endocr Disord. 2022. PMID: 34986816 Free PMC article.
BACKGROUND: Primary macronodular adrenal hyperplasia (PMAH), previously termed ACTH-independent macronodular adrenal hyperplasia (AIMAH), is a rare cause of Cushing's syndrome usually characterized by functioning adrenal macronodules and …
BACKGROUND: Primary macronodular adrenal hyperplasia (PMAH), previously termed ACTH-independent macronodular …
Update of Genetic and Molecular Causes of Adrenocortical Hyperplasias Causing Cushing Syndrome.
Berthon A, Bertherat J. Berthon A, et al. Horm Metab Res. 2020 Aug;52(8):598-606. doi: 10.1055/a-1061-7349. Epub 2020 Feb 25. Horm Metab Res. 2020. PMID: 32097969 Review.
These hyperplasias have been classified in two categories based on the adrenal nodule size: the micronodular types include Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and isolated Micronodular Adrenal Disease (iMAD) and the macronodular also named Primary Bilateral …
These hyperplasias have been classified in two categories based on the adrenal nodule size: the micronodular types include Primary Pigmented …
Adrenal hyperplasia and tumours in mice in connection with aberrant pituitary-gonadal function.
Bernichtein S, Peltoketo H, Huhtaniemi I. Bernichtein S, et al. Mol Cell Endocrinol. 2009 Mar 5;300(1-2):164-8. doi: 10.1016/j.mce.2008.10.005. Epub 2008 Oct 19. Mol Cell Endocrinol. 2009. PMID: 19007852 Review.
Our findings may have relevance to the human pathogenesis of macronodular adrenal hyperplasia and postmenopausal adrenocortical tumours. A distinctly different adrenal response was observed in TG mice overexpressing LH or CG, or a constitutively activa …
Our findings may have relevance to the human pathogenesis of macronodular adrenal hyperplasia and postmenopausal adreno …
The Relationship Between Baseline Cortisol Levels and Surgery Method of Primary Bilateral Macronodular Adrenal Hyperplasia.
Gao J, Yu Z, Sun F, Xu B, Zhang C, Wang H, Lu J, Lei T. Gao J, et al. Horm Metab Res. 2022 Jun;54(6):354-360. doi: 10.1055/a-1850-2169. Epub 2022 Jun 13. Horm Metab Res. 2022. PMID: 35697044 Free article.
Aim was to explore the associations between baseline cortisol levels and surgery method of primary bilateral macronodular adrenal hyperplasia (PBMAH). We retrospectively reviewed the clinical features and management of 30 patients (18 females and 12 males) wh …
Aim was to explore the associations between baseline cortisol levels and surgery method of primary bilateral macronodular adrenal …
The effect of unilateral adrenalectomy on patients with primary bilateral macronodular adrenal hyperplasia.
Yu Z, Gao J, Sun F. Yu Z, et al. Hormones (Athens). 2023 Jun;22(2):235-242. doi: 10.1007/s42000-023-00428-8. Epub 2023 Feb 17. Hormones (Athens). 2023. PMID: 36800160 Free PMC article.
PURPOSE: To evaluate the long-term effect of unilateral adrenalectomy (uADX) on patients with primary bilateral macronodular adrenal hyperplasia (PBMAH). METHODS: We retrospectively reviewed 29 patients (including 11 men and 18 women) with PBMAH and Cushing's …
PURPOSE: To evaluate the long-term effect of unilateral adrenalectomy (uADX) on patients with primary bilateral macronodular adren …
Clinical Spectrum of Adrenal Cushing's Syndrome and the Caution for Interpretation of Adrenocorticotrophic Hormone: A Single-Center Experience.
Gosavi V, Lila A, Memon SS, Sarathi V, Thakkar K, Dalvi A, Malhotra G, Prakash G, Patil V, Shah NS, Bandgar T. Gosavi V, et al. Horm Metab Res. 2022 Feb;54(2):57-66. doi: 10.1055/a-1735-3232. Epub 2022 Feb 7. Horm Metab Res. 2022. PMID: 35130566 Free article.
To emphasize caution for interpretation of plasma adrenocorticotropic hormone (ACTH), as a spuriously unsuppressed ACTH level by immunometric assay may lead to therapeutic misadventures in adrenal CS. DESIGN: Retrospective, single-center, observational study. METHODS: Fift …
To emphasize caution for interpretation of plasma adrenocorticotropic hormone (ACTH), as a spuriously unsuppressed ACTH level by immunometri …
Role of adrenal venous sampling in the differential diagnosis and treatment protocol of ACTH-independent Cushing's syndrome with bilateral adrenal lesions.
An X, Chen T, Mo D, Shen S, Zhang D, Zhang T, Tian H, Li Y, Li J, Li L, Wu N, Zhu Y, Ren Y. An X, et al. Endocrine. 2023 Sep;81(3):562-572. doi: 10.1007/s12020-023-03395-7. Epub 2023 Jun 24. Endocrine. 2023. PMID: 37354283
RESULTS: Patients with AICS were clinically diagnosed based on clinical signs, results of functional tests and the presence of bilateral adrenal lesions as observed on computed tomography imaging. An AV to IVC PAC ratio greater than 2 confirmed successful AVS. ...
RESULTS: Patients with AICS were clinically diagnosed based on clinical signs, results of functional tests and the presence of bilateral adr …
Intraadrenal corticotropin in bilateral macronodular adrenal hyperplasia.
Louiset E, Duparc C, Young J, Renouf S, Tetsi Nomigni M, Boutelet I, Libé R, Bram Z, Groussin L, Caron P, Tabarin A, Grunenberger F, Christin-Maitre S, Bertagna X, Kuhn JM, Anouar Y, Bertherat J, Lefebvre H. Louiset E, et al. N Engl J Med. 2013 Nov 28;369(22):2115-25. doi: 10.1056/NEJMoa1215245. N Engl J Med. 2013. PMID: 24283225 Free article.
BACKGROUND: Bilateral macronodular adrenal hyperplasia is a rare cause of primary adrenal Cushing's syndrome. ...Thus, the disease has been termed corticotropin-independent macronodular adrenal hyperplasia. We examined the abnormal produc …
BACKGROUND: Bilateral macronodular adrenal hyperplasia is a rare cause of primary adrenal Cushing's syndrome. ...Thus, …
62 results